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Published in: BMC Pregnancy and Childbirth 1/2014

Open Access 01-12-2014 | Research article

Severe maternal morbidity and maternal near miss in the extremes of reproductive age: results from a national cross- sectional multicenter study

Authors: Fernando César Oliveira Jr, Fernanda Garanhani Surita, João Luiz Pinto e Silva, José Guilherme Cecatti, Mary Angela Parpinelli, Samira M Haddad, Maria Laura Costa, Rodolfo Carvalho Pacagnella, Maria Helena Sousa, João Paulo Souza, The Brazilian Network for Surveillance of Severe Maternal Morbidity Study Group

Published in: BMC Pregnancy and Childbirth | Issue 1/2014

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Abstract

Background

The aim of this study was to assess severe maternal morbidity (SMM) and near miss (NM) cases among adolescent girls and women over 35 years of age in the Brazilian Network for Surveillance of Severe Maternal Morbidity, using a set of standard criteria, compared to pregnant women aged 20 to 34 years.

Methods

A cross-sectional multicenter study conducted in 27 referral obstetric units in Brazil. All pregnant women admitted to these centers during a one-year period of prospective surveillance were screened to identify cases of maternal death (MD), NM and other SMM. Indicators of maternal morbidity and mortality were evaluated for the three age groups. Sociodemographic, clinical and obstetric characteristics, gestational and perinatal outcomes, main causes of morbidity and delays in care were also compared. Two multiple analysis models were performed, to estimate the adjusted prevalence ratio for identified factors that were independently associated with the occurrence of severe maternal outcome (SMO = MNM + MD).

Results

Among SMM and MD cases identified, the proportion of adolescent girls and older women were 17% each. The risk of MNM or death was 25% higher among older women. Maternal near miss ratio and maternal mortality ratios increased with age, but these ratios were also higher among adolescents aged 10 to 14, although the absolute numbers were low. On multivariate analysis, younger age was not identified as an independent risk factor for SMO, while this was true for older age (PR 1.25; 1.07-1.45).

Conclusions

SMO was high among women below 14 years of age and increased with age in Brazilian pregnant women.
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Literature
1.
go back to reference Ham P, Allen C: Adolescent health screening and counseling. Am Fam Physician. 2012, 86 (12): 1109-1116.PubMed Ham P, Allen C: Adolescent health screening and counseling. Am Fam Physician. 2012, 86 (12): 1109-1116.PubMed
2.
go back to reference Jacobsson B, Ladfors L, Milsom I: Advanced maternal age and adverse perinatal outcome. Obstet Gynecol. 2004, 104: 727-733. 10.1097/01.AOG.0000140682.63746.be.CrossRefPubMed Jacobsson B, Ladfors L, Milsom I: Advanced maternal age and adverse perinatal outcome. Obstet Gynecol. 2004, 104: 727-733. 10.1097/01.AOG.0000140682.63746.be.CrossRefPubMed
3.
go back to reference Lamminpää R, Vehviläinen-Julkunen K, Gissler M, Heinonen S: Preeclampsia complicated by advanced maternal age: a registry-based study on primiparous women in Finland 1997-2008. BMC Pregnancy Childbirth. 2012, 12: 47-10.1186/1471-2393-12-47.CrossRefPubMedPubMedCentral Lamminpää R, Vehviläinen-Julkunen K, Gissler M, Heinonen S: Preeclampsia complicated by advanced maternal age: a registry-based study on primiparous women in Finland 1997-2008. BMC Pregnancy Childbirth. 2012, 12: 47-10.1186/1471-2393-12-47.CrossRefPubMedPubMedCentral
4.
go back to reference Pattinson RC, Hall M: Near misses: an useful adjunct to maternal death enquiries. Br Med Bull. 2003, 67: 231-243. 10.1093/bmb/ldg007.CrossRefPubMed Pattinson RC, Hall M: Near misses: an useful adjunct to maternal death enquiries. Br Med Bull. 2003, 67: 231-243. 10.1093/bmb/ldg007.CrossRefPubMed
5.
go back to reference Cecatti JG, Souza JP, Parpinelli MA, Haddad SM, Camargo RS, Pacagnella RC, Silveira C, Zanardi DT, Costa ML, Silva JL P e, Passini R, Surita FG, Sousa MH, Calderon IM, Say L, Pattinson RC, Brazilian Network for Surveillance of Severe Maternal Morbidity: Brazilian network for the surveillance of maternal potentially life threatening morbidity and maternal near-miss and a multidimensional evaluation of their long term consequences. Reprod Health. 2009, 6: 15-10.1186/1742-4755-6-15.CrossRefPubMedPubMedCentral Cecatti JG, Souza JP, Parpinelli MA, Haddad SM, Camargo RS, Pacagnella RC, Silveira C, Zanardi DT, Costa ML, Silva JL P e, Passini R, Surita FG, Sousa MH, Calderon IM, Say L, Pattinson RC, Brazilian Network for Surveillance of Severe Maternal Morbidity: Brazilian network for the surveillance of maternal potentially life threatening morbidity and maternal near-miss and a multidimensional evaluation of their long term consequences. Reprod Health. 2009, 6: 15-10.1186/1742-4755-6-15.CrossRefPubMedPubMedCentral
6.
go back to reference Pattinson R, Say L, Souza JP, Van Den Broek N, Rooney C, WHO Working Group on Maternal Mortality and Morbidity Classifications: WHO maternal death and near-miss classifications. Bull World Health Org. 2009, 87 (10): 734-10.2471/BLT.09.071001.CrossRefPubMedPubMedCentral Pattinson R, Say L, Souza JP, Van Den Broek N, Rooney C, WHO Working Group on Maternal Mortality and Morbidity Classifications: WHO maternal death and near-miss classifications. Bull World Health Org. 2009, 87 (10): 734-10.2471/BLT.09.071001.CrossRefPubMedPubMedCentral
7.
go back to reference Cecatti JG, Souza JP, Parpinelli MA, Sousa MH, Amaral E: Research on severe maternal morbidities and near-misses in Brazil: what we have learned. Reprod Health Matters. 2007, 15 (30): 125-133. 10.1016/S0968-8080(07)30333-9.CrossRefPubMed Cecatti JG, Souza JP, Parpinelli MA, Sousa MH, Amaral E: Research on severe maternal morbidities and near-misses in Brazil: what we have learned. Reprod Health Matters. 2007, 15 (30): 125-133. 10.1016/S0968-8080(07)30333-9.CrossRefPubMed
8.
go back to reference Say L, Souza JP, Pattinson RC, WHO working group on Maternal Mortality and Morbidity classifications: Maternal near miss–towards a standard tool for monitoring quality of maternal health care. Best Practice Res Clin Obstet Gynaecol. 2009, 23 (3): 287-296. 10.1016/j.bpobgyn.2009.01.007.CrossRef Say L, Souza JP, Pattinson RC, WHO working group on Maternal Mortality and Morbidity classifications: Maternal near miss–towards a standard tool for monitoring quality of maternal health care. Best Practice Res Clin Obstet Gynaecol. 2009, 23 (3): 287-296. 10.1016/j.bpobgyn.2009.01.007.CrossRef
10.
go back to reference Cecatti JG, Souza JP, Oliveira Neto AF, Parpinelli MA, Sousa MH, Say L, Pattinson RC: Pre-validation of the WHO organ dysfunction based criteria for identification of maternal near miss. Reprod Health. 2011, 8: 22-10.1186/1742-4755-8-22.CrossRefPubMedPubMedCentral Cecatti JG, Souza JP, Oliveira Neto AF, Parpinelli MA, Sousa MH, Say L, Pattinson RC: Pre-validation of the WHO organ dysfunction based criteria for identification of maternal near miss. Reprod Health. 2011, 8: 22-10.1186/1742-4755-8-22.CrossRefPubMedPubMedCentral
11.
go back to reference Tunçalp O, Hindin MJ, Souza JP, Chou D, Say L: The prevalence of maternal near miss: a systematic review. BJOG. 2012, 119 (6): 653-661. 10.1111/j.1471-0528.2012.03294.x.CrossRefPubMed Tunçalp O, Hindin MJ, Souza JP, Chou D, Say L: The prevalence of maternal near miss: a systematic review. BJOG. 2012, 119 (6): 653-661. 10.1111/j.1471-0528.2012.03294.x.CrossRefPubMed
12.
go back to reference Conde-Agudelo A, Belizán JM, Lammers C: Maternal-perinatal morbidity and mortality associated with adolescent pregnancy in Latin America: cross-sectional study. Am J Obstet Gynecol. 2005, 192 (2): 342-349. 10.1016/j.ajog.2004.10.593.CrossRefPubMed Conde-Agudelo A, Belizán JM, Lammers C: Maternal-perinatal morbidity and mortality associated with adolescent pregnancy in Latin America: cross-sectional study. Am J Obstet Gynecol. 2005, 192 (2): 342-349. 10.1016/j.ajog.2004.10.593.CrossRefPubMed
15.
go back to reference Koyanagi A, Zhang J, Dagvadorj A, Hirayama F, Shibuya K, Souza JP, Gülmezoglu AM: Macrosomia in 23 developing countries: an analysis of a multicountry, facility-based, cross-sectional survey. Lancet. 2013, 381 (9865): 476-483. 10.1016/S0140-6736(12)61605-5.CrossRefPubMed Koyanagi A, Zhang J, Dagvadorj A, Hirayama F, Shibuya K, Souza JP, Gülmezoglu AM: Macrosomia in 23 developing countries: an analysis of a multicountry, facility-based, cross-sectional survey. Lancet. 2013, 381 (9865): 476-483. 10.1016/S0140-6736(12)61605-5.CrossRefPubMed
16.
go back to reference Bayrampour H, Heaman M: Advanced maternal age and the risk of cesarean birth: a systematic review. Birth. 2010, 37: 219-226. 10.1111/j.1523-536X.2010.00409.x.CrossRefPubMed Bayrampour H, Heaman M: Advanced maternal age and the risk of cesarean birth: a systematic review. Birth. 2010, 37: 219-226. 10.1111/j.1523-536X.2010.00409.x.CrossRefPubMed
17.
go back to reference Cleary-Goldman J, Malone FD, Vidaver J, Ball RH, Nyberg DA, Comstock CH, Saade GR, Eddleman KA, Klugman S, Dugoff L, Timor-Tritsch IE, Craigo SD, Carr SR, Wolfe HM, Bianchi DW, D’Alton M, FASTER Consortium: Impact of maternal age on obstetric outcome. Obstet Gynecol. 2005, 105 (5 Pt 1): 983-990.CrossRefPubMed Cleary-Goldman J, Malone FD, Vidaver J, Ball RH, Nyberg DA, Comstock CH, Saade GR, Eddleman KA, Klugman S, Dugoff L, Timor-Tritsch IE, Craigo SD, Carr SR, Wolfe HM, Bianchi DW, D’Alton M, FASTER Consortium: Impact of maternal age on obstetric outcome. Obstet Gynecol. 2005, 105 (5 Pt 1): 983-990.CrossRefPubMed
18.
go back to reference Haddad SM, Cecatti JG, Parpinelli MA, Souza JP, Costa ML, Sousa MH, Surita FG, Pinto E, Silva JL, Pacagnella RC, Camargo RS, Bahamondes MV, Zotareli V, Gurgel LT, Say L, Pattinson RC, National Network for the Surveillance of Severe Maternal Morbidity Group: From planning to practice: building the national network for the Surveillance of Severe Maternal Morbidity. BMC Public Health. 2011, 11: 283-10.1186/1471-2458-11-283.CrossRefPubMedPubMedCentral Haddad SM, Cecatti JG, Parpinelli MA, Souza JP, Costa ML, Sousa MH, Surita FG, Pinto E, Silva JL, Pacagnella RC, Camargo RS, Bahamondes MV, Zotareli V, Gurgel LT, Say L, Pattinson RC, National Network for the Surveillance of Severe Maternal Morbidity Group: From planning to practice: building the national network for the Surveillance of Severe Maternal Morbidity. BMC Public Health. 2011, 11: 283-10.1186/1471-2458-11-283.CrossRefPubMedPubMedCentral
19.
go back to reference Haddad SM, Sousa MH, Cecatti JG, Parpinelli MA, Costa ML, Souza JP, Brazilian Network for Surveillance of Severe Maternal Morbidity Group: Intraclass correlation coefficients in the Brazilian network for surveillance of severe maternal morbidity study. BMC Pregnancy Childbirth. 2012, 12 (1): 101-10.1186/1471-2393-12-101.CrossRefPubMedPubMedCentral Haddad SM, Sousa MH, Cecatti JG, Parpinelli MA, Costa ML, Souza JP, Brazilian Network for Surveillance of Severe Maternal Morbidity Group: Intraclass correlation coefficients in the Brazilian network for surveillance of severe maternal morbidity study. BMC Pregnancy Childbirth. 2012, 12 (1): 101-10.1186/1471-2393-12-101.CrossRefPubMedPubMedCentral
21.
go back to reference Lisonkova S, Liu S, Bartholomew S, Liston RM, Joseph KS, Maternal Health Study Group of the Canadian Perinatal Surveillance System: Temporal trends in maternal mortality in Canada II: estimates based on hospitalization data. J Obstet Gynaecol Can. 2011, 33 (10): 1020-1030.CrossRefPubMed Lisonkova S, Liu S, Bartholomew S, Liston RM, Joseph KS, Maternal Health Study Group of the Canadian Perinatal Surveillance System: Temporal trends in maternal mortality in Canada II: estimates based on hospitalization data. J Obstet Gynaecol Can. 2011, 33 (10): 1020-1030.CrossRefPubMed
22.
go back to reference Gray KE, Wallace ER, Nelson KR, Reed SD, Schiff MA: Population-based study of risk factors for severe maternal morbidity. Paediatr Perinat Epidemiol. 2012, 26 (6): 506-514. 10.1111/ppe.12011.CrossRefPubMedPubMedCentral Gray KE, Wallace ER, Nelson KR, Reed SD, Schiff MA: Population-based study of risk factors for severe maternal morbidity. Paediatr Perinat Epidemiol. 2012, 26 (6): 506-514. 10.1111/ppe.12011.CrossRefPubMedPubMedCentral
23.
go back to reference Zwart JJ, Richters JM, Ory F, de Vries JI, Bloemenkamp KW, van Roosmalen J: Severe maternal morbidity during pregnancy, delivery and puerperium in the Netherlands: a nationwide population-based study of 371,000 pregnancies. BJOG. 2008, 115 (7): 842-850. 10.1111/j.1471-0528.2008.01713.x.CrossRefPubMed Zwart JJ, Richters JM, Ory F, de Vries JI, Bloemenkamp KW, van Roosmalen J: Severe maternal morbidity during pregnancy, delivery and puerperium in the Netherlands: a nationwide population-based study of 371,000 pregnancies. BJOG. 2008, 115 (7): 842-850. 10.1111/j.1471-0528.2008.01713.x.CrossRefPubMed
24.
go back to reference Souza JP, Cecatti JG, Parpinelli MA, Sousa MH, Lago TG, Pacagnella RC, Camargo RS: Maternal morbidity and near miss in the community: findings from the 2006 Brazilian demographic health survey. BJOG. 2010, 117 (13): 1586-1592. 10.1111/j.1471-0528.2010.02746.x.CrossRefPubMed Souza JP, Cecatti JG, Parpinelli MA, Sousa MH, Lago TG, Pacagnella RC, Camargo RS: Maternal morbidity and near miss in the community: findings from the 2006 Brazilian demographic health survey. BJOG. 2010, 117 (13): 1586-1592. 10.1111/j.1471-0528.2010.02746.x.CrossRefPubMed
25.
go back to reference Victora CG, Matijasevich A, Silveira MF, Santos IS, Barros AJ, Barros FC: Socio-economic and ethnic group inequities in antenatal care quality in the public and private sector in Brazil. Health Policy Plann. 2010, 25: 253-261. 10.1093/heapol/czp065.CrossRef Victora CG, Matijasevich A, Silveira MF, Santos IS, Barros AJ, Barros FC: Socio-economic and ethnic group inequities in antenatal care quality in the public and private sector in Brazil. Health Policy Plann. 2010, 25: 253-261. 10.1093/heapol/czp065.CrossRef
26.
go back to reference Victora CG, Aquino EM, do Carmo Leal M, Monteiro CA, Barros FC, Szwarcwald CL: Maternal and child health in Brazil: progress and challenges. Lancet. 2011, 377 (9780): 1863-1876. 10.1016/S0140-6736(11)60138-4.CrossRefPubMed Victora CG, Aquino EM, do Carmo Leal M, Monteiro CA, Barros FC, Szwarcwald CL: Maternal and child health in Brazil: progress and challenges. Lancet. 2011, 377 (9780): 1863-1876. 10.1016/S0140-6736(11)60138-4.CrossRefPubMed
Metadata
Title
Severe maternal morbidity and maternal near miss in the extremes of reproductive age: results from a national cross- sectional multicenter study
Authors
Fernando César Oliveira Jr
Fernanda Garanhani Surita
João Luiz Pinto e Silva
José Guilherme Cecatti
Mary Angela Parpinelli
Samira M Haddad
Maria Laura Costa
Rodolfo Carvalho Pacagnella
Maria Helena Sousa
João Paulo Souza
The Brazilian Network for Surveillance of Severe Maternal Morbidity Study Group
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2014
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/1471-2393-14-77

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