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BMC Neurology

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Open Access 01-12-2021 | Vestibular Neuronitis | Research article

Risk factors related balance disorder for patients with dizziness/vertigo

Authors: Zhentang Cao, Cuiting Zhu, Yanan Zhou, Yan Wang, Meimei Chen, Yi Ju, Xingquan Zhao

Published in: BMC Neurology | Issue 1/2021

Abstract

Background

When dizziness/vertigo patients presented with balance disorder, it will bring severe morbidity. There is currently lack of research to explore risk factor related balance disorder in dizziness patients, especially in those who walk independently.

Aim

To investigate risk factors related balance disorder in dizziness/vertigo patients who walk independently.

Methods

Medical data of 1002 dizziness/vertigo patients registered in vertigo/balance disorder registration database were reviewed. The demographic data, medical history, and risk factors for atherosclerosis (AS) were collected. Enrolled dizziness/vertigo patients could walk independently, completed Romberg test, videonystagmography (VNG), and limits of stability (LOS). The subjective imbalance was patient complained of postural symptom when performing Romberg test. Multivariable logistic regression analyzed risk factors related balance disorder. The receiver operating characteristic (ROC) curve evaluated the utility of regression model.

Results

Five hundred fifty-three dizziness/vertigo patients who walk independently were included in the final analysis. According to LOS, patients were divided into 334 (60%) normal balance and 219 (40%) balance disorder. Compared with normal balance, patients with balance disorder were older (P = 0.045) and had more risk factors for AS (P<0.0001). The regression showed that risk factors for AS (OR 1.494, 95% CI 1.198–1.863), subjective imbalance (OR 4.835, 95% CI 3.047–7.673), and abnormality of optokinetic nystagmus (OR 8.308, 95% CI 1.576–43.789) were related to balance disorder. The sensitivity and specificity of model were 71 and 63% (P<0.0001). The area under the curve (AUC) was 0.721.

Conclusions

Risk factors for AS, subjective imbalance, and abnormality of optokinetic nystagmus were predictors for balance disorder in patients with dizziness/vertigo who walk independently.

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Title: Risk factors related balance disorder for patients with dizziness/vertigo
Authors: Zhentang Cao
Cuiting Zhu
Yanan Zhou
Yan Wang
Meimei Chen
Yi Ju
Xingquan Zhao
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Vestibular Neuronitis
Benign Paroxysmal Positional Vertigo
Arterial Occlusive Disease
Nystagmus
Published in: BMC Neurology / Issue 1/2021
Electronic ISSN: 1471-2377
DOI: https://doi.org/10.1186/s12883-021-02188-7

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Risk factors related balance disorder for patients with dizziness/vertigo

Abstract

Background

Aim

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Aim

Methods

Results

Conclusions

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