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BMC Neurology
Published in: BMC Neurology 1/2018

Open Access 01-12-2018 | Research article

MR imaging features of benign retroperitoneal paragangliomas and schwannomas

Authors: Yanguang Shen, Yan Zhong, Haiyi Wang, Lu Ma, Yingwei Wang, Kun Zhang, Zhonghua Sun, Huiyi Ye

Published in: BMC Neurology | Issue 1/2018

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Abstract

Background

To determine whether MRI feature analysis can differentiate benign retroperitoneal extra-adrenal paragangliomas and schwannomas.

Methods

The MRI features of 50 patients with confirmed benign retroperitoneal extra-adrenal paragangliomas and schwannomas were retrospectively reviewed by two radiologists blinded to the histopathologic diagnosis. These features were compared between two types of tumours by use of the Mann-Whitney test and binary logistic regression. The patients’ clinical characteristics were reviewed.

Results

Analysis of MRI images from 50 patients revealed no significant differences in the quantitative MRI features of lesion size, ratio of diameter and apparent diffusion coefficient. There were significant differences in the qualitative MRI features of location, necrosis, cysts and degree of tumour enhancement for two readers, with no significant differences in the other qualitative MRI features between these tumours. The combination of necrosis with degree of tumour enhancement during the arterial phase increased the probability that a retroperitoneal mass would represent retroperitoneal extra-adrenal paraganglioma as opposed to schwannoma.

Conclusion

We have presented the largest series of MRI features of both benign retroperitoneal extra-adrenal paragangliomas and schwannomas. Some MRI features assist in the differentiation between these tumours, with imaging features consisting of necrosis and avid enhancement during the arterial phase, suggestive of retroperitoneal extra-adrenal paragangliomas.
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Metadata
Title
MR imaging features of benign retroperitoneal paragangliomas and schwannomas
Authors
Yanguang Shen
Yan Zhong
Haiyi Wang
Lu Ma
Yingwei Wang
Kun Zhang
Zhonghua Sun
Huiyi Ye
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2018
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-017-0998-8

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