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Open Access 01-12-2016 | Research article

The relation between angioarchitectural factors of developmental venous anomaly and concomitant sporadic cavernous malformation

Authors: Tengfei Yu, Xing Liu, Xiangjiang Lin, Chuanfeng Bai, Jizong Zhao, Junting Zhang, Liwei Zhang, Zhen Wu, Shuo Wang, Yuanli Zhao, Guolu Meng

Published in: BMC Neurology | Issue 1/2016

Abstract

Background

Past studies found that cerebral developmental venous anomaly (DVA) is often concurrent with cavernous malformation (CM). But the reason of the concurrency remains unknown. The purpose of this study was to confirm whether angioarchitectural factors relate to the concurrence and which angioarchitectural factors can induce the concurrency.

Methods

DVA cases were selected from the records of the same 3.0 T MR. The DVA cases was divided into two group which are DVA group and DVA concurrent with CM group. 8 angioarchitectural factors of the DVAs were selected and measured. Statistical analysis was performed by the Pearson chi-square statistic,analysis of variance (ANOVA) and multi-factor logistic regression analysis.

Results

Five hundred three DVA lesions were found and 76 CM lesions coexisting with DVA. In the single factor analysis, all the 8 angioarchitectural factors of DVA were related to the concurrency. In the multivariate analysis, 6 angioarchitectural factors. Result of multi-factor logistic regression analysis is Logit(P) = -4.858-0.932(Location) + 1.616(Direction) + 1.757(Torsion) + 0.237(Number) + 2.119(Stenosis rate of medullary vein)-0.015(Angle), goodness of fit is 90.1 %.

Conclusions

The angioarchitectural factors of DVA are related to the concurrency of DVA and CM. 6 angioarchitectural factors may induce the concurrency.

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Title: The relation between angioarchitectural factors of developmental venous anomaly and concomitant sporadic cavernous malformation
Authors: Tengfei Yu
Xing Liu
Xiangjiang Lin
Chuanfeng Bai
Jizong Zhao
Junting Zhang
Liwei Zhang
Zhen Wu
Shuo Wang
Yuanli Zhao
Guolu Meng
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: BMC Neurology / Issue 1/2016
Electronic ISSN: 1471-2377
DOI: https://doi.org/10.1186/s12883-016-0691-3

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

The relation between angioarchitectural factors of developmental venous anomaly and concomitant sporadic cavernous malformation

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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