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Published in: BMC Neurology 1/2015

Open Access 01-12-2015 | Research article

Temporal trends and risk factors for readmission for infections, gastrointestinal and immobility complications after an incident hospitalisation for stroke in Scotland between 1997 and 2005

Authors: James Lewsey, Osaretin Ebueku, Pardeep S Jhund, Michelle Gillies, Jim WT Chalmers, Adam Redpath, Andrew Briggs, Matthew Walters, Peter Langhorne, Simon Capewell, John JV McMurray, Kate MacIntyre

Published in: BMC Neurology | Issue 1/2015

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Abstract

Background

Improvements in stroke management have led to increases in the numbers of stroke survivors over the last decade and there has been a corresponding increase of hospital readmissions after an initial stroke hospitalisation. The aim of this study was to examine the one year risk of having a readmission due to infective, gastrointestinal or immobility (IGI) complications and to identify temporal trends and any risk factors.

Methods

Using a cohort of first hospitalised for stroke patients who were discharged alive, time to first event (readmission for IGI complications or death) within 1 year was analysed in a competing risks framework using cumulative incidence methods. Regression on the cumulative incidence function was used to model the risks of having an outcome using the covariates age, sex, socioeconomic status, comorbidity, discharge destination and length of hospital stay.

Results

There were a total of 51,182 patients discharged alive after an incident stroke hospitalisation in Scotland between 1997–2005, and 7,747 (15.1%) were readmitted for IGI complications within a year of the discharge. Comparing incident stroke hospitalisations in 2005 with 1997, the adjusted risk of IGI readmission did not increase (HR = 1.00 95% CI (0.90, 1.11). However, there was a higher risk of IGI readmission with increasing levels of deprivation (most deprived fifth vs. least deprived fifth HR = 1.16 (1.08, 1.26).

Conclusions

Approximately 15 in 100 patients discharged alive after an incident hospitalisation for stroke in Scotland between 1997 and 2005 went on to have an IGI readmission within one year. The proportion of readmissions did not change over the study period but those living in deprived areas had an increased risk.
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Literature
1.
go back to reference Strong K, Mathers C, Bonita R. Preventing stroke: saving lives around the world. Lancet Neurol. 2007;6:182–7.CrossRefPubMed Strong K, Mathers C, Bonita R. Preventing stroke: saving lives around the world. Lancet Neurol. 2007;6:182–7.CrossRefPubMed
3.
go back to reference Gulliford MC, Charlton J, Rudd A, Wolfe CD, Toschke AM. Declining 1-year case-fatality of stroke and increasing coverage of vascular risk management: population based cohort study. J Neurol Neurosurg Psychiatry. 2010;81:416–22.CrossRefPubMedPubMedCentral Gulliford MC, Charlton J, Rudd A, Wolfe CD, Toschke AM. Declining 1-year case-fatality of stroke and increasing coverage of vascular risk management: population based cohort study. J Neurol Neurosurg Psychiatry. 2010;81:416–22.CrossRefPubMedPubMedCentral
4.
go back to reference Fonarow GC, Smith EE, Reeves MJ, Pan W, Olson D, Hernandez AF, et al. Hospital-level variation in mortality and rehospitalization for medicare beneficiaries with acute ischemic stroke. Stroke. 2011;42:159–66.CrossRefPubMed Fonarow GC, Smith EE, Reeves MJ, Pan W, Olson D, Hernandez AF, et al. Hospital-level variation in mortality and rehospitalization for medicare beneficiaries with acute ischemic stroke. Stroke. 2011;42:159–66.CrossRefPubMed
5.
go back to reference Lichtman JH, Leifheit-Limson EC, Jones SB, Watanabe E, Bernheim SM, Phipps MS, et al. Predictors of hospital readmission after stroke: a systematic review. Stroke. 2010;41:2525–33.CrossRefPubMedPubMedCentral Lichtman JH, Leifheit-Limson EC, Jones SB, Watanabe E, Bernheim SM, Phipps MS, et al. Predictors of hospital readmission after stroke: a systematic review. Stroke. 2010;41:2525–33.CrossRefPubMedPubMedCentral
6.
go back to reference Hardie K, Jamrozik K, Hankey GJ, Broadhurst RJ, Anderson C. Trends in five-year survival and risk of recurrent stroke after first-ever stroke in the Perth community stroke study. Cerebrovasc Dis. 2005;19:179–85.CrossRefPubMed Hardie K, Jamrozik K, Hankey GJ, Broadhurst RJ, Anderson C. Trends in five-year survival and risk of recurrent stroke after first-ever stroke in the Perth community stroke study. Cerebrovasc Dis. 2005;19:179–85.CrossRefPubMed
7.
go back to reference Mohan KM, Crichton SL, Grieve AP, Rudd AG, Wolfe CDA, Heuschmann PU. Frequency and predictors for the risk of stroke recurrence up to 10 years after stroke: the South London Stroke Register. J Neurol Neurosurg Psychiatry. 2009;80:1012–8.CrossRefPubMed Mohan KM, Crichton SL, Grieve AP, Rudd AG, Wolfe CDA, Heuschmann PU. Frequency and predictors for the risk of stroke recurrence up to 10 years after stroke: the South London Stroke Register. J Neurol Neurosurg Psychiatry. 2009;80:1012–8.CrossRefPubMed
8.
go back to reference Lewsey J, Jhund P, Gillies M, Chalmers J, Redpath A, Briggs A, et al. Temporal trends in hospitalisation for stroke recurrence following incident hospitalisation for stroke in Scotland. BMC Med. 2010;8:23.CrossRefPubMedPubMedCentral Lewsey J, Jhund P, Gillies M, Chalmers J, Redpath A, Briggs A, et al. Temporal trends in hospitalisation for stroke recurrence following incident hospitalisation for stroke in Scotland. BMC Med. 2010;8:23.CrossRefPubMedPubMedCentral
9.
go back to reference Kilkenny MF, Longworth M, Pollack M, Levi C, Cadilhac DA. Factors associated with 28-day hospital readmission after stroke in Australia. Stroke. 2013;44:2260–8.CrossRefPubMed Kilkenny MF, Longworth M, Pollack M, Levi C, Cadilhac DA. Factors associated with 28-day hospital readmission after stroke in Australia. Stroke. 2013;44:2260–8.CrossRefPubMed
10.
go back to reference Bravata DM, Ho S-Y, Meehan TP, Brass LM, Concato J. Readmission and death after hospitalization for acute ischemic stroke: 5-year follow-up in the medicare population. Stroke. 2007;38:1899–904.CrossRefPubMed Bravata DM, Ho S-Y, Meehan TP, Brass LM, Concato J. Readmission and death after hospitalization for acute ischemic stroke: 5-year follow-up in the medicare population. Stroke. 2007;38:1899–904.CrossRefPubMed
11.
go back to reference Bohannon RW, Lee N. Association of physical functioning with same hospital readmission after stroke. Am J Phys Med Rehabil. 2004;83:434–8.CrossRefPubMed Bohannon RW, Lee N. Association of physical functioning with same hospital readmission after stroke. Am J Phys Med Rehabil. 2004;83:434–8.CrossRefPubMed
12.
go back to reference Tseng M-C, Lin H-J. Readmission after hospitalization for stroke in Taiwan: results from a national sample. J Neurol Sci. 2009;284:52–5.CrossRefPubMed Tseng M-C, Lin H-J. Readmission after hospitalization for stroke in Taiwan: results from a national sample. J Neurol Sci. 2009;284:52–5.CrossRefPubMed
13.
go back to reference Lin H-J, Chang W-L, Tseng M-C. Readmission after stroke in a hospital-based registry: risk, etiologies, and risk factors. Neurology. 2011;76:438–43.CrossRefPubMed Lin H-J, Chang W-L, Tseng M-C. Readmission after stroke in a hospital-based registry: risk, etiologies, and risk factors. Neurology. 2011;76:438–43.CrossRefPubMed
14.
go back to reference Bamford J, Dennis M, Sandercock P, Burn J, Warlow C. The frequency, causes and timing of death within 30 days of a first stroke: the Oxfordshire community stroke project. J Neurol Neurosurg Psychiatry. 1990;53:824–9.CrossRefPubMedPubMedCentral Bamford J, Dennis M, Sandercock P, Burn J, Warlow C. The frequency, causes and timing of death within 30 days of a first stroke: the Oxfordshire community stroke project. J Neurol Neurosurg Psychiatry. 1990;53:824–9.CrossRefPubMedPubMedCentral
15.
go back to reference Ottenbacher KJ, Graham JE, Ottenbacher AJ, Lee J, Al Snih S, Karmarkar A, et al. Hospital readmission in persons with stroke following postacute inpatient rehabilitation. J Gerontol A Biol Sci Med Sci. 2012;67:875–81.CrossRefPubMedPubMedCentral Ottenbacher KJ, Graham JE, Ottenbacher AJ, Lee J, Al Snih S, Karmarkar A, et al. Hospital readmission in persons with stroke following postacute inpatient rehabilitation. J Gerontol A Biol Sci Med Sci. 2012;67:875–81.CrossRefPubMedPubMedCentral
19.
go back to reference Satagopan JM, Ben Porat L, Berwick M, Robson M, Kutler D, Auerbach AD. A note on competing risks in survival data analysis. Br J Cancer. 2004;91:1229–35.CrossRefPubMedPubMedCentral Satagopan JM, Ben Porat L, Berwick M, Robson M, Kutler D, Auerbach AD. A note on competing risks in survival data analysis. Br J Cancer. 2004;91:1229–35.CrossRefPubMedPubMedCentral
20.
go back to reference Kim HT. Cumulative incidence in competing risks data and competing risks regression analysis. Clin Cancer Res. 2007;13:559–65.CrossRefPubMed Kim HT. Cumulative incidence in competing risks data and competing risks regression analysis. Clin Cancer Res. 2007;13:559–65.CrossRefPubMed
21.
go back to reference Jason PF, Gray RJ. A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc. 1999;94:496–509.CrossRef Jason PF, Gray RJ. A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc. 1999;94:496–509.CrossRef
22.
go back to reference Lyratzopoulos G, Havely D, Gemmell I, Cook GA. Factors influencing emergency medical readmission risk in a UK district general hospital: a prospective study. BMC Emerg Med. 2005;5:1.CrossRefPubMedPubMedCentral Lyratzopoulos G, Havely D, Gemmell I, Cook GA. Factors influencing emergency medical readmission risk in a UK district general hospital: a prospective study. BMC Emerg Med. 2005;5:1.CrossRefPubMedPubMedCentral
23.
go back to reference Chuang KY, Wu SC, Ma AH, Chen YH, Wu CL. Identifying factors associated with hospital readmissions among stroke patients in Taipei. J Nursing Res. 2005;13:117–28.CrossRef Chuang KY, Wu SC, Ma AH, Chen YH, Wu CL. Identifying factors associated with hospital readmissions among stroke patients in Taipei. J Nursing Res. 2005;13:117–28.CrossRef
24.
go back to reference Kane RL, Chen Q, Finch M, Blewett L, Burns R, Moskowitz M. Functional outcomes of posthospital care for stroke and hip fracture patients under medicare. J Am Geriatr Soc. 1998;46:1525–33.CrossRefPubMed Kane RL, Chen Q, Finch M, Blewett L, Burns R, Moskowitz M. Functional outcomes of posthospital care for stroke and hip fracture patients under medicare. J Am Geriatr Soc. 1998;46:1525–33.CrossRefPubMed
25.
go back to reference Jia H, Zheng Y, Reker DM, Cowper DC, Wu SS, Vogel WB, et al. Multiple system utilization and mortality for veterans with stroke. Stroke. 2007;38:355–60.CrossRefPubMed Jia H, Zheng Y, Reker DM, Cowper DC, Wu SS, Vogel WB, et al. Multiple system utilization and mortality for veterans with stroke. Stroke. 2007;38:355–60.CrossRefPubMed
26.
go back to reference Sun Y, Toh MPHS. Impact of diabetes mellitus (DM) on the health-care utilization and clinical outcomes of patients with stroke in Singapore. Value Health. 2009;12:S101–5.CrossRefPubMed Sun Y, Toh MPHS. Impact of diabetes mellitus (DM) on the health-care utilization and clinical outcomes of patients with stroke in Singapore. Value Health. 2009;12:S101–5.CrossRefPubMed
Metadata
Title
Temporal trends and risk factors for readmission for infections, gastrointestinal and immobility complications after an incident hospitalisation for stroke in Scotland between 1997 and 2005
Authors
James Lewsey
Osaretin Ebueku
Pardeep S Jhund
Michelle Gillies
Jim WT Chalmers
Adam Redpath
Andrew Briggs
Matthew Walters
Peter Langhorne
Simon Capewell
John JV McMurray
Kate MacIntyre
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2015
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-014-0257-1

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