Skip to main content
Top
Published in: BMC Nephrology 1/2018

Open Access 01-12-2018 | Case report

A case of ureteral myeloid sarcoma post-renal transplantation

Published in: BMC Nephrology | Issue 1/2018

Login to get access

Abstract

Background

Significant attention has been directed toward the high incidence of malignant tumours that occur post-transplantation. However, there are few reports of myeloid sarcomas (MSs) following renal transplantation.

Case presentation

This case report describes a 26-year-old male patient who presented with repeatedly high creatinine levels and hydronephrosis six months post-renal transplantation. Surgical pathology revealed ureteral MS; however, the tumour recurred following resection. Bone marrow biopsy indicated that the patient also had acute promyelocytic leukaemia. The tumour was treated with local radiotherapy, and the leukaemia was treated with systemic chemotherapy. The patient’s conditions were satisfactory at the one-year follow-up.

Conclusions

This report is the first to describe a ureteral MS post-renal transplantation. Our findings suggest that surgical resection combined with radiotherapy and chemotherapy can help control the status of patients with this condition.
Literature
1.
go back to reference Farrugia D, Mahboob S, Cheshire J, et al. Malignancy-related mortality following kidney transplantation is common. Kidney Int. 2014;85:1395–403.CrossRefPubMed Farrugia D, Mahboob S, Cheshire J, et al. Malignancy-related mortality following kidney transplantation is common. Kidney Int. 2014;85:1395–403.CrossRefPubMed
2.
go back to reference Birkeland SA, Løkkegaard H, Storm HH. Cancer risk in patients on dialysis and after renal transplantation. Lancet. 2000;355:1886–7.CrossRefPubMed Birkeland SA, Løkkegaard H, Storm HH. Cancer risk in patients on dialysis and after renal transplantation. Lancet. 2000;355:1886–7.CrossRefPubMed
3.
go back to reference Kidney Disease: Improving Global Outcomes (KDIGO) Transplant Work Group. KDIGO clinical practice guideline for the care of kidney transplant recipients. Am J Transplant. 2009;9(Suppl 3):S1–155. Kidney Disease: Improving Global Outcomes (KDIGO) Transplant Work Group. KDIGO clinical practice guideline for the care of kidney transplant recipients. Am J Transplant. 2009;9(Suppl 3):S1–155.
4.
go back to reference Vajdic CM, McDonald SP, McCredie MR, et al. Cancer incidence before and after kidney transplantation. JAMA. 2006;296:2823–31.CrossRefPubMed Vajdic CM, McDonald SP, McCredie MR, et al. Cancer incidence before and after kidney transplantation. JAMA. 2006;296:2823–31.CrossRefPubMed
5.
go back to reference Campidelli C1, Agostinelli C, Stitson R, et al. Myeloid sarcoma: extramedullary manifestation of myeloid disorders. Am J Clin Pathol 2009;132:426–437. Campidelli C1, Agostinelli C, Stitson R, et al. Myeloid sarcoma: extramedullary manifestation of myeloid disorders. Am J Clin Pathol 2009;132:426–437.
6.
go back to reference Quinlan SC, Morton LM, Pfeiffer RM, et al. Increased risk for lymphoid and myeloid neoplasms in elderly solid-organ transplant recipients. Cancer Epidemiol Biomark Prev. 2010;19:1229–37.CrossRef Quinlan SC, Morton LM, Pfeiffer RM, et al. Increased risk for lymphoid and myeloid neoplasms in elderly solid-organ transplant recipients. Cancer Epidemiol Biomark Prev. 2010;19:1229–37.CrossRef
7.
go back to reference Tsimberidou AM1, Kantarjian HM, Wen S, et al. Myeloid sarcoma is associated with superior event-free survival and overall survival compared with acute myeloid leukemia. Cancer. 2008;113:1370–8.CrossRefPubMedPubMedCentral Tsimberidou AM1, Kantarjian HM, Wen S, et al. Myeloid sarcoma is associated with superior event-free survival and overall survival compared with acute myeloid leukemia. Cancer. 2008;113:1370–8.CrossRefPubMedPubMedCentral
8.
go back to reference AlGhunaim M, AlSuwaida A, Zaidi SN, et al. First case report of acute myeloid sarcoma post renal transplant. Transplant Proc. 2014;46:2411–3.CrossRefPubMed AlGhunaim M, AlSuwaida A, Zaidi SN, et al. First case report of acute myeloid sarcoma post renal transplant. Transplant Proc. 2014;46:2411–3.CrossRefPubMed
9.
go back to reference Palanisamy A, Persad P, Koty PP, et al. Donor-derived myeloid sarcoma in two kidney transplant recipients from a single donor. Case Rep Nephrol. 2015;2015:821346.PubMedPubMedCentral Palanisamy A, Persad P, Koty PP, et al. Donor-derived myeloid sarcoma in two kidney transplant recipients from a single donor. Case Rep Nephrol. 2015;2015:821346.PubMedPubMedCentral
10.
go back to reference Shen J, Du X, Diao X, et al. Myeloid sarcoma presenting with multiple skin and subcutaneous mass without leukemic manifestations after renal transplantation. Transplant Proc. 2015;47:2227–32.CrossRefPubMed Shen J, Du X, Diao X, et al. Myeloid sarcoma presenting with multiple skin and subcutaneous mass without leukemic manifestations after renal transplantation. Transplant Proc. 2015;47:2227–32.CrossRefPubMed
Metadata
Title
A case of ureteral myeloid sarcoma post-renal transplantation
Publication date
01-12-2018
Published in
BMC Nephrology / Issue 1/2018
Electronic ISSN: 1471-2369
DOI
https://doi.org/10.1186/s12882-018-0838-0

Other articles of this Issue 1/2018

BMC Nephrology 1/2018 Go to the issue