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Published in: BMC Medical Imaging 1/2018

Open Access 01-12-2018 | Research article

Gadoxetic acid-enhanced magnetic resonance imaging significantly influences the clinical course in patients with colorectal liver metastases

Authors: B. G. Sibinga Mulder, K. Visser, S. Feshtali, A. L. Vahrmeijer, R. J. Swijnenburg, H. H. Hartgrink, R. van den Boom, M. C. Burgmans, J. S. D. Mieog

Published in: BMC Medical Imaging | Issue 1/2018

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Abstract

Background

Gadoxetic acid (Primovist™)-enhanced magnetic resonance imaging (P-MRI) scans have higher accuracy and increased detection of small colorectal liver metastases (CRLM) compared to CT scans or conventional MRI scans. But, P-MRI scans are still inconsistently acquired in the diagnostic work up of patients with CRLM. The aim of this study was to determine the influence of P-MRI scans on treatment plan proposition and subsequently the clinical course of the patient.

Methods

Eighty-three consecutive patients with potentially resectable CRLM based on a conventional CT scan underwent P-MRI scanning prior to treatment. Treatment plans proposed by the multidisciplinary team were compared before and after P-MRI scanning and related to the final treatment and diagnosis, the accuracy for the CT scan and P-MRI scan was calculated.

Results

P-MRI scans led to a change of treatment in 15 patients (18%) and alteration of extensiveness of local therapy in another 17 patients (20%). All changes were justified leading to an accuracy of 93% for treatment proposition based on P-MRI scan, compared to an accuracy of 75% for the CT scan.

Conclusions

P-MRI scans provide additional information that can aid in proposing the most suitable treatment for patients with CRLM and might prevent short-term reintervention.
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Metadata
Title
Gadoxetic acid-enhanced magnetic resonance imaging significantly influences the clinical course in patients with colorectal liver metastases
Authors
B. G. Sibinga Mulder
K. Visser
S. Feshtali
A. L. Vahrmeijer
R. J. Swijnenburg
H. H. Hartgrink
R. van den Boom
M. C. Burgmans
J. S. D. Mieog
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Medical Imaging / Issue 1/2018
Electronic ISSN: 1471-2342
DOI
https://doi.org/10.1186/s12880-018-0289-x

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