Published in:
Open Access 01-12-2019 | Amphotericin B | Case report
Disseminated histoplasmosis in an immunocompetent individual diagnosed with gastrointestinal endoscopy: a case report
Published in: BMC Infectious Diseases | Issue 1/2019
Login to get accessAbstract
Background
Histoplasmosis is one of the invasive fungal infections and presents with symptoms mainly in the lungs. Disseminated histoplasmosis (DH) is rare and its lesions in the gastrointestinal tract are even uncommon. The concomitant involvement of the upper and lower gastrointestinal tract has never been described in the immunocompetent individuals.
Case presentation
A 44-year-old immunocompetent Chinese man presented with fever, hepatosplenomegaly, fungal esophagitis and protuberant lesions with central depression and erosion along the mucous membrane of the colon. The patient was diagnosed as disseminated histoplasmosis by gastrointestinal endoscopy.
Conclusions
Histoplasmosis should be taken caution in patients with fever and hepatosplenomegaly. Actions should be taken to avoid its disseminated infection associated high mortality.