Skip to main content
Top
Published in: BMC Infectious Diseases 1/2019

Open Access 01-12-2019 | Ringworm of the hair | Case report

The first case report of kerion-type scalp mycosis caused by Aspergillus protuberus

Authors: Jinjing Jia, Min Chen, Xiumei Mo, Junfeng Liu, Fenggen Yan, Zhengxiao Li, Shaoqiong Xie, Dacan Chen

Published in: BMC Infectious Diseases | Issue 1/2019

Login to get access

Abstract

Background

Scalp mycosis is often caused by dermatophytes and was so called tinea capitis. There is no published report caused by Aspergillus protuberus. We report a rare case of kerion-type scalp mycosis caused by A. protuberus.

Case presentation

A 5-year-old girl developed pyogenic mass with pain for 8 days and got a fever for 2 days prior to admission. Surgical incision and drainage of the mass, intravenous cefuroxime and metronidazole in the local hospital aggravated the skin lesions. Species identification was performed by observation of morphologic and biochemical characteristicsand sequencing of the internal transcribed spacer (ITS) and β-tubulin (BT2). Treatment with oral and topical antifungal agents was effective with no relapse during the six months of clinical follow-up.

Conclusions

Aspergillusis a opportunistic pathogenic fungus and its infection occurs mostly in patients with underlying conditions and immunocompromised statuses. So far no report of kerion-type scalp infection has been reported. The first case of kerion-type scalp mycosis caused by A. protuberus was described to highlight the importance of mycological examination that helps to recognize rare pathogenic fungi. Any boggy lesion with hair loss over the scalp and non-responsive to antibiotics should be suspected as resulting from fungal infection, and mycological examination should be performed, especially in children.
Literature
1.
go back to reference Siqueira JP, Sutton DA, García D, Gené J, Thomson P, Wiederhold N, Guarro J. Species diversity of Aspergillus section Versicolores in clinical samples and antifungal susceptibilityFungal. Biol. 2016;120:1458–67. Siqueira JP, Sutton DA, García D, Gené J, Thomson P, Wiederhold N, Guarro J. Species diversity of Aspergillus section Versicolores in clinical samples and antifungal susceptibilityFungal. Biol. 2016;120:1458–67.
2.
go back to reference Charles MP, Noyal MJ, Easow JM, M R. Invasive pulmonary aspergillosis caused by Aspergillusversicolor in a patient on mechanical ventilation. Australas Med J. 2011;4:632–4.CrossRef Charles MP, Noyal MJ, Easow JM, M R. Invasive pulmonary aspergillosis caused by Aspergillusversicolor in a patient on mechanical ventilation. Australas Med J. 2011;4:632–4.CrossRef
3.
go back to reference Al-Hatmi AMS, Castro MA, de Hoog GS, Badali H, Alvarado VF, Verweij PE, Meis JF, Zago VV. Epidemiology of Aspergillus species causing keratitis in Mexico. Mycoses. 2019;62:144–51.CrossRef Al-Hatmi AMS, Castro MA, de Hoog GS, Badali H, Alvarado VF, Verweij PE, Meis JF, Zago VV. Epidemiology of Aspergillus species causing keratitis in Mexico. Mycoses. 2019;62:144–51.CrossRef
4.
go back to reference Perri P, Campa C, Incorvaia C, Parmeggiani F, Lamberti G, Costagliola C, Sebastiani A. Endogenous Aspergillusversicolorendophthalmitis in an immuno-competent HIV-positive patient. Mycopathologia. 2005;160:259–61.CrossRef Perri P, Campa C, Incorvaia C, Parmeggiani F, Lamberti G, Costagliola C, Sebastiani A. Endogenous Aspergillusversicolorendophthalmitis in an immuno-competent HIV-positive patient. Mycopathologia. 2005;160:259–61.CrossRef
5.
go back to reference Al-Hatmi AM, van Diepeningen AD, Curfs-Breuker I, de Hoog GS, Meis JF. Specific antifungal susceptibility profiles of opportunists in the Fusariumfujikuroi complex. J AntimicrobChemother. 2015;70:1068–71. Al-Hatmi AM, van Diepeningen AD, Curfs-Breuker I, de Hoog GS, Meis JF. Specific antifungal susceptibility profiles of opportunists in the Fusariumfujikuroi complex. J AntimicrobChemother. 2015;70:1068–71.
6.
go back to reference Stielow JB, Lévesque CA, Seifert KA, Meyer W, Iriny L, Smits D, Renfurm R, Verkley GJ, Groenewald M, Chaduli D, Lomascolo A, Welti S, Lesage-Meessen L, Favel A, Al-Hatmi AM, Damm U, Yilmaz N, Houbraken J, Lombard L, Quaedvlieg W, Binder M, Vaas LA, Vu D, Yurkov A, Begerow D, Roehl O, Guerreiro M, Fonseca A, Samerpitak K, van Diepeningen AD, Dolatabadi S, Moreno LF, Casaregola S, Mallet S, Jacques N, Roscini L, Egidi E, Bizet C, Garcia-Hermoso D, Martín MP, Deng S, Groenewald JZ, Boekhout T, de Beer ZW, Barnes I, Duong TA, Wingfield MJ, de Hoog GS, Crous PW, Lewis CT, Hambleton S, Moussa TA, Al-Zahrani HS, Almaghrabi OA, Louis-Seize G, Assabgui R, McCormick W, Omer G, Dukik K, Cardinali G, Eberhardt U, de Vries M, Robert V. One fungus, which genes? Development and assessment of universal primers for potential secondary fungal DNA barcodes. Persoonia. 2015;35:242–63.CrossRef Stielow JB, Lévesque CA, Seifert KA, Meyer W, Iriny L, Smits D, Renfurm R, Verkley GJ, Groenewald M, Chaduli D, Lomascolo A, Welti S, Lesage-Meessen L, Favel A, Al-Hatmi AM, Damm U, Yilmaz N, Houbraken J, Lombard L, Quaedvlieg W, Binder M, Vaas LA, Vu D, Yurkov A, Begerow D, Roehl O, Guerreiro M, Fonseca A, Samerpitak K, van Diepeningen AD, Dolatabadi S, Moreno LF, Casaregola S, Mallet S, Jacques N, Roscini L, Egidi E, Bizet C, Garcia-Hermoso D, Martín MP, Deng S, Groenewald JZ, Boekhout T, de Beer ZW, Barnes I, Duong TA, Wingfield MJ, de Hoog GS, Crous PW, Lewis CT, Hambleton S, Moussa TA, Al-Zahrani HS, Almaghrabi OA, Louis-Seize G, Assabgui R, McCormick W, Omer G, Dukik K, Cardinali G, Eberhardt U, de Vries M, Robert V. One fungus, which genes? Development and assessment of universal primers for potential secondary fungal DNA barcodes. Persoonia. 2015;35:242–63.CrossRef
7.
go back to reference Kechia FA, Kouoto EA, Nkoa T, Nweze EI, Fokoua DC, Fosso S, Somo MR. Epidemiology of tineacapitis among school-age children in Meiganga, Cameroon. J Mycol Med. 2014;24:129–34.CrossRef Kechia FA, Kouoto EA, Nkoa T, Nweze EI, Fokoua DC, Fosso S, Somo MR. Epidemiology of tineacapitis among school-age children in Meiganga, Cameroon. J Mycol Med. 2014;24:129–34.CrossRef
8.
go back to reference Hillary T, Suys E. An outbreak of tineacapitis in elderly patients. Int J Dermatol. 2014;53:e101–3.CrossRef Hillary T, Suys E. An outbreak of tineacapitis in elderly patients. Int J Dermatol. 2014;53:e101–3.CrossRef
9.
10.
11.
go back to reference Elewski BE. Tineacapitis: a current perspective. J Am AcadDermatol. 2000;42:1–20 quiz 21-4.CrossRef Elewski BE. Tineacapitis: a current perspective. J Am AcadDermatol. 2000;42:1–20 quiz 21-4.CrossRef
12.
go back to reference Zaraa I, Hawilo A, Aounallah A, Trojjet S, El Euch D, Mokni M, Ben Osman A. Inflammatory Tineacapitis: a 12-year study and a review of the literature. Mycoses. 2013;56:110–6.CrossRef Zaraa I, Hawilo A, Aounallah A, Trojjet S, El Euch D, Mokni M, Ben Osman A. Inflammatory Tineacapitis: a 12-year study and a review of the literature. Mycoses. 2013;56:110–6.CrossRef
13.
go back to reference von Laer Tschudin L, Laffitte E, Baudraz-Rosselet F, Dushi G, Hohlfeld J, de Buys Roessingh AS. Tineacapitis: no incision nor excision. J PediatrSurg. 2007;42:e33–6. von Laer Tschudin L, Laffitte E, Baudraz-Rosselet F, Dushi G, Hohlfeld J, de Buys Roessingh AS. Tineacapitis: no incision nor excision. J PediatrSurg. 2007;42:e33–6.
14.
go back to reference Borsa BA, Özgün G, Houbraken J, Ökmen F. The first case of persistent vaginitis due to Aspergillusprotuberus in an immunocompetent patient. Mikrobiyol Bul. 2015;49:130–4.CrossRef Borsa BA, Özgün G, Houbraken J, Ökmen F. The first case of persistent vaginitis due to Aspergillusprotuberus in an immunocompetent patient. Mikrobiyol Bul. 2015;49:130–4.CrossRef
15.
go back to reference Rotoli M, Sascaro G, Cavalieri S. Aspergillusversicolor infection of the external auditory canal successfullytreated with terbinafne. Dermatology. 2001;202:143.CrossRef Rotoli M, Sascaro G, Cavalieri S. Aspergillusversicolor infection of the external auditory canal successfullytreated with terbinafne. Dermatology. 2001;202:143.CrossRef
16.
go back to reference Liu Z, Hou T, Shen Q, Liao W, Xu H. Osteomyelitis of sacral spine caused by Aspergillusversicolor with neurologic defcits. Chin Med J. 1995;108:472–5.PubMed Liu Z, Hou T, Shen Q, Liao W, Xu H. Osteomyelitis of sacral spine caused by Aspergillusversicolor with neurologic defcits. Chin Med J. 1995;108:472–5.PubMed
17.
go back to reference Veraldi S, Chiaratti A, Harak H. Onychomycosis caused by Aspergillusversicolor. Mycoses. 2010;53:363–5.PubMed Veraldi S, Chiaratti A, Harak H. Onychomycosis caused by Aspergillusversicolor. Mycoses. 2010;53:363–5.PubMed
18.
go back to reference Kakourou T, Uksal U. European Society for Pediatric Dermatology.Guidelines for the management of tineacapitis in children. PediatrDermatol. 2010;27:226–8. Kakourou T, Uksal U. European Society for Pediatric Dermatology.Guidelines for the management of tineacapitis in children. PediatrDermatol. 2010;27:226–8.
19.
go back to reference Patel GA, Schwartz RA. Tineacapitis: still an unsolved problem? Mycoses. 2011;54:183–8.CrossRef Patel GA, Schwartz RA. Tineacapitis: still an unsolved problem? Mycoses. 2011;54:183–8.CrossRef
Metadata
Title
The first case report of kerion-type scalp mycosis caused by Aspergillus protuberus
Authors
Jinjing Jia
Min Chen
Xiumei Mo
Junfeng Liu
Fenggen Yan
Zhengxiao Li
Shaoqiong Xie
Dacan Chen
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2019
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-019-4144-7

Other articles of this Issue 1/2019

BMC Infectious Diseases 1/2019 Go to the issue