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Open Access 01-12-2018 | Case report

Maternal and infant death after probable vertical transmission of chikungunya virus in Brazil – case report

Authors: Rhaquel de Morais Alves Barbosa Oliveira, Francisca Kalline de Almeida Barreto, Ana Maria Peixoto Cabral Maia, Ileana Pitombeira Gomes, Adriana Rocha Simião, Rebeca Bandeira Barbosa, Adilina Soares Romeiro Rodrigues, Kilma Wanderley Lopes, Fernanda Montenegro de Carvalho Araújo, Regina Lúcia Sousa do Vale, John Washington Cavalcante, Luciano Pamplona de Góes Cavalcanti

Published in: BMC Infectious Diseases | Issue 1/2018

Abstract

Background

Chikungunya virus infection in neonates is relatively rare and can lead to death.

Case presentation

We report the occurrence of the first death of a mother and child after probable vertical transmission of chikungunya virus in Brazil. A 28-year-old pregnant woman with hypertension presented with symptoms compatible with an arboviral disease at 34 weeks’ gestation. She developed preeclampsia with severe respiratory failure which resulted in the emergency cesarean section, and the patient died 12 days after the onset of symptoms. The pre-term newborn weighed 2535 g, with an Apgar score of 4/8. He was referred to the neonatal ICU with neutrophilia and thrombocytopenia, several seizure episodes, and hemorrhagic disorders, which resulted in death. Chikungunya IgM antibody was detected in the cerebrospinal fluid.

Conclusions

We present the first documented maternal and neonatal death in Brazil after probable chikungunya infection during pregnancy.

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Title: Maternal and infant death after probable vertical transmission of chikungunya virus in Brazil – case report
Authors: Rhaquel de Morais Alves Barbosa Oliveira
Francisca Kalline de Almeida Barreto
Ana Maria Peixoto Cabral Maia
Ileana Pitombeira Gomes
Adriana Rocha Simião
Rebeca Bandeira Barbosa
Adilina Soares Romeiro Rodrigues
Kilma Wanderley Lopes
Fernanda Montenegro de Carvalho Araújo
Regina Lúcia Sousa do Vale
John Washington Cavalcante
Luciano Pamplona de Góes Cavalcanti
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: BMC Infectious Diseases / Issue 1/2018
Electronic ISSN: 1471-2334
DOI: https://doi.org/10.1186/s12879-018-3243-1

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