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Published in: BMC Infectious Diseases 1/2016

Open Access 01-12-2016 | Case report

Human meningitis due to Streptococcus suis in Lomé, Togo: a case report

Authors: Mireille Prince-David, Mounerou Salou, Corinne Marois-Créhan, Komi Assogba, Céline Plainvert, Koffi A. Balogou, Claire Poyart, Asmaa Tazi

Published in: BMC Infectious Diseases | Issue 1/2016

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Abstract

Background

Streptococcus suis is a zoonotic pathogen which represents the leading cause of meningitis in Southeast Asia and an emerging pathogen in the Western world, the main risk factor for infection being contact with pigs. In Africa, the prevalence of S. suis infections in swine and humans is largely unrecognized, with only one recent report of a limited case series.

Case presentation

We describe a human case of meningitis due to S. suis in a 32-year-old man living in Togo. The patient had no particular medical history and no risk factors for immunodeficiency but reported regular contact with pork products. Using specific immunological and molecular methods, we characterized the isolate as S. suis serotype 2, ST1, one the most prevalent and virulent clone worldwide. The outcome was favorable after one week of adapted antibiotic therapy but the patient was left with severe hearing disorders.

Conclusions

This work highlights the emergence of this pathogen in Africa and reinforces the need for accurate epidemiological and surveillance studies of S. suis infections and for educating clinicians and exposed groups in non-endemic countries.
Literature
1.
go back to reference Huong VTL, Ha N, Huy NT, Horby P, Nghia HDT, Thiem VD, et al. Epidemiology, Clinical Manifestations, and Outcomes of Streptococcus suis Infection in Humans. Emerg Infect Dis. 2014;20:1105–14.PubMedPubMedCentral Huong VTL, Ha N, Huy NT, Horby P, Nghia HDT, Thiem VD, et al. Epidemiology, Clinical Manifestations, and Outcomes of Streptococcus suis Infection in Humans. Emerg Infect Dis. 2014;20:1105–14.PubMedPubMedCentral
2.
go back to reference Van Samkar A, Brouwer MC, Schultsz C, Van der Ende A, Van de Beek D. Streptococcus suis Meningitis: A Systematic Review and Meta-analysis. PLoS Negl Trop Dis. 2015;9:e0004191.CrossRefPubMedPubMedCentral Van Samkar A, Brouwer MC, Schultsz C, Van der Ende A, Van de Beek D. Streptococcus suis Meningitis: A Systematic Review and Meta-analysis. PLoS Negl Trop Dis. 2015;9:e0004191.CrossRefPubMedPubMedCentral
3.
go back to reference Marois C, Bougeard S, Gottschalk M, Kobisch M. Multiplex PCR assay for detection of Streptococcus suis species and serotypes 2 and 1/2 in tonsils of live and dead pigs. J Clin Microbiol. 2004;42:3169–75.CrossRefPubMedPubMedCentral Marois C, Bougeard S, Gottschalk M, Kobisch M. Multiplex PCR assay for detection of Streptococcus suis species and serotypes 2 and 1/2 in tonsils of live and dead pigs. J Clin Microbiol. 2004;42:3169–75.CrossRefPubMedPubMedCentral
4.
go back to reference King SJ, Leigh JA, Heath PJ, Luque I, Tarradas C, Dowson CG, et al. Development of a multilocus sequence typing scheme for the pig pathogen Streptococcus suis: identification of virulent clones and potential capsular serotype exchange. J Clin Microbiol. 2002;40:3671–80.CrossRefPubMedPubMedCentral King SJ, Leigh JA, Heath PJ, Luque I, Tarradas C, Dowson CG, et al. Development of a multilocus sequence typing scheme for the pig pathogen Streptococcus suis: identification of virulent clones and potential capsular serotype exchange. J Clin Microbiol. 2002;40:3671–80.CrossRefPubMedPubMedCentral
5.
go back to reference Gottschalk M, Higgins R, Jacques M, Mittal KR, Henrichsen J. Description of 14 new capsular types of Streptococcus suis. J Clin Microbiol. 1989;27:2633–6.PubMedPubMedCentral Gottschalk M, Higgins R, Jacques M, Mittal KR, Henrichsen J. Description of 14 new capsular types of Streptococcus suis. J Clin Microbiol. 1989;27:2633–6.PubMedPubMedCentral
6.
go back to reference Schultsz C, Jansen E, Keijzers W, Rothkamp A, Duim B, Wagenaar JA, et al. Differences in the population structure of invasive Streptococcus suis strains isolated from pigs and from humans in The Netherlands. PLoS ONE. 2012;7, e33854.CrossRefPubMedPubMedCentral Schultsz C, Jansen E, Keijzers W, Rothkamp A, Duim B, Wagenaar JA, et al. Differences in the population structure of invasive Streptococcus suis strains isolated from pigs and from humans in The Netherlands. PLoS ONE. 2012;7, e33854.CrossRefPubMedPubMedCentral
7.
go back to reference Tall H, Njanpop-Lafourcade B-M, Mounkoro D, Tidjani L, Agbenoko K, Alassani I, et al. Identification of Streptococcus suis Meningitis through Population-Based Surveillance, Togo, 2010–2014. Emerg Infect Dis. 2016;22:1262–4.CrossRefPubMedPubMedCentral Tall H, Njanpop-Lafourcade B-M, Mounkoro D, Tidjani L, Agbenoko K, Alassani I, et al. Identification of Streptococcus suis Meningitis through Population-Based Surveillance, Togo, 2010–2014. Emerg Infect Dis. 2016;22:1262–4.CrossRefPubMedPubMedCentral
Metadata
Title
Human meningitis due to Streptococcus suis in Lomé, Togo: a case report
Authors
Mireille Prince-David
Mounerou Salou
Corinne Marois-Créhan
Komi Assogba
Céline Plainvert
Koffi A. Balogou
Claire Poyart
Asmaa Tazi
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2016
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-016-2006-0

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