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Published in: BMC Infectious Diseases 1/2016

Open Access 01-12-2016 | Research article

Using the 4 pillars™ practice transformation program to increase adult influenza vaccination and reduce missed opportunities in a randomized cluster trial

Authors: Chyongchiou J. Lin, Mary Patricia Nowalk, Valory N. Pavlik, Anthony E. Brown, Song Zhang, Jonathan M. Raviotta, Krissy K. Moehling, Mary Hawk, Edmund M. Ricci, Donald B. Middleton, Suchita Patel, Jeannette E. South-Paul, Richard K. Zimmerman

Published in: BMC Infectious Diseases | Issue 1/2016

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Abstract

Background

An evidence-based, step-by-step guide, the 4 Pillars™ Practice Transformation Program, was the foundation of an intervention to increase adult immunizations in primary care and was tested in a randomized controlled cluster trial. The purpose of this study is to report changes in influenza immunization rates and on factors related to receipt of influenza vaccine.

Methods

Twenty five primary care practices were recruited in 2013, stratified by city (Houston, Pittsburgh), location (rural, urban, suburban) and type (family medicine, internal medicine), and randomized to the intervention (n = 13) or control (n = 12) in Year 1 (2013-14). A follow-up intervention occurred in Year 2 (2014-15). Demographic and vaccination data were derived from de-identified electronic medical record extractions.

Results

A cohort of 70,549 adults seen in their respective practices (n = 24 with 1 drop out) at least once each year was followed. Baseline mean age was 55.1 years, 35 % were men, 21 % were non-white and 35 % were Hispanic. After one year, both intervention and control arms significantly (P < 0.001) increased influenza vaccination, with average increases of 2.7 to 6.5 percentage points. In regression analyses, likelihood of influenza vaccination was significantly higher in sites with lower percentages of patients with missed opportunities (P < 0.001) and, after adjusting for missed opportunities, the intervention further improved vaccination rates in Houston (lower baseline rates) but not Pittsburgh (higher baseline rates). In the follow-up intervention, the likelihood of vaccination increased for both intervention sites and those that reduced missed opportunities (P < 0.005).

Conclusions

Reducing missed opportunities across the practice increases likelihood of influenza vaccination of adults. The 4 Pillars™ Practice Transformation Program provides strategies for reducing missed opportunities to vaccinate adults.

Trial registration

This study was registered as a clinical trial on 03/20/2013 at ClinicalTrials.gov, Clinical Trial Registry Number: NCT01868334, with a date of enrollment of the first participant to the trial of April 1, 2013.
Literature
5.
go back to reference Jessop AB, Dumas H, Moser CA. Delivering influenza vaccine to high-risk adults: subspecialty physician practices. Am J Med Qual. 2013;28(3):232–7.CrossRefPubMed Jessop AB, Dumas H, Moser CA. Delivering influenza vaccine to high-risk adults: subspecialty physician practices. Am J Med Qual. 2013;28(3):232–7.CrossRefPubMed
6.
go back to reference Nowak GJ, Sheedy K, Bursey K, Smith TM, Basket M. Promoting influenza vaccination: Insights from a qualitative meta-analysis of 14 years of influenza-related communications research by U.S. Centers for Disease Control and Prevention (CDC). Vaccine. 2015;33(24):2741–56.CrossRefPubMed Nowak GJ, Sheedy K, Bursey K, Smith TM, Basket M. Promoting influenza vaccination: Insights from a qualitative meta-analysis of 14 years of influenza-related communications research by U.S. Centers for Disease Control and Prevention (CDC). Vaccine. 2015;33(24):2741–56.CrossRefPubMed
8.
go back to reference Koh HK, Sebelius KG. Promoting prevention through the affordable care act. New Engl J Med. 2010;363(14):1296–9.CrossRefPubMed Koh HK, Sebelius KG. Promoting prevention through the affordable care act. New Engl J Med. 2010;363(14):1296–9.CrossRefPubMed
9.
go back to reference Stewart AM, Cox MA. State law and influenza vaccination of health care personnel. Vaccine. 2013;31(5):827–32.CrossRefPubMed Stewart AM, Cox MA. State law and influenza vaccination of health care personnel. Vaccine. 2013;31(5):827–32.CrossRefPubMed
12.
go back to reference Zimmerman RK, Brown AE, Pavlik VN, Moehling KK, Raviotta JM, Lin CJ, Zhang S, Hawk M, Kyle S, Patel S et al. Using the 4 Pillars™ Practice Transformation Program to increase pneumococcal immunizations for older adults: A cluster randomized trial. J Am Geriatr Soc. 2016 (In Press). Zimmerman RK, Brown AE, Pavlik VN, Moehling KK, Raviotta JM, Lin CJ, Zhang S, Hawk M, Kyle S, Patel S et al. Using the 4 Pillars™ Practice Transformation Program to increase pneumococcal immunizations for older adults: A cluster randomized trial. J Am Geriatr Soc. 2016 (In Press).
13.
go back to reference Campbell MK, Piaggio G, Elbourne DR DGA. Consort 2010 statement: extension to cluster randomised trials. BMJ. 2012;345:e5661.CrossRefPubMed Campbell MK, Piaggio G, Elbourne DR DGA. Consort 2010 statement: extension to cluster randomised trials. BMJ. 2012;345:e5661.CrossRefPubMed
14.
go back to reference Melinkovich P, Hammer A, Staudenmaier A, Berg M. Improving pediatric immunization rates in a safety-net delivery system. Jt Comm J Qual Patient Saf. 2007;33(4):205–10.CrossRefPubMed Melinkovich P, Hammer A, Staudenmaier A, Berg M. Improving pediatric immunization rates in a safety-net delivery system. Jt Comm J Qual Patient Saf. 2007;33(4):205–10.CrossRefPubMed
15.
go back to reference Baskerville NB, Liddy C, Hogg W. Systematic review and meta-analysis of practice facilitation within primary care settings. Ann Fam Med. 2012;10(1):63–74.CrossRefPubMedPubMedCentral Baskerville NB, Liddy C, Hogg W. Systematic review and meta-analysis of practice facilitation within primary care settings. Ann Fam Med. 2012;10(1):63–74.CrossRefPubMedPubMedCentral
16.
go back to reference Fixsen D, Naoom S, Blase K, Friedman R, Wallace F. Implementation Research: A Synthesis of the Literature. Tampa: University of South Florida, Louis de la Parte Florida Mental Health Institute, The National Implementation Research Network (FMHI Publication #231); 2005. Fixsen D, Naoom S, Blase K, Friedman R, Wallace F. Implementation Research: A Synthesis of the Literature. Tampa: University of South Florida, Louis de la Parte Florida Mental Health Institute, The National Implementation Research Network (FMHI Publication #231); 2005.
17.
go back to reference Saltelli A, Tarantola S, Campolongo F, Ratto M. Sensitivity Analysis in Practice: A Guide to Assessing Scientific Models. New York: Willey; 2004. Saltelli A, Tarantola S, Campolongo F, Ratto M. Sensitivity Analysis in Practice: A Guide to Assessing Scientific Models. New York: Willey; 2004.
18.
go back to reference Agresti A. Categorical Data Analysis. 2nd ed. New York: Wiley-Interscience; 2002.CrossRef Agresti A. Categorical Data Analysis. 2nd ed. New York: Wiley-Interscience; 2002.CrossRef
20.
go back to reference Watts B, Lawrence RH, Singh S, Wagner C, Augustine S, Singh MK. Implementation of quality improvement skills by primary care teams: case study of a large academic practice. J Prim Care Community Health. 2014;5(2):101–6.CrossRefPubMed Watts B, Lawrence RH, Singh S, Wagner C, Augustine S, Singh MK. Implementation of quality improvement skills by primary care teams: case study of a large academic practice. J Prim Care Community Health. 2014;5(2):101–6.CrossRefPubMed
21.
go back to reference Fu LY, Weissman M, McLaren R, Thomas C, Campbell J, Mbafor J, Doshi U, Cora-Bramble D. Improving the quality of immunization delivery to an at-risk population: a comprehensive approach. Pediatrics. 2012;129(2):e496–503.CrossRefPubMedPubMedCentral Fu LY, Weissman M, McLaren R, Thomas C, Campbell J, Mbafor J, Doshi U, Cora-Bramble D. Improving the quality of immunization delivery to an at-risk population: a comprehensive approach. Pediatrics. 2012;129(2):e496–503.CrossRefPubMedPubMedCentral
22.
go back to reference Nowalk MP, Zimmerman RK, Feghali J. Missed opportunities for adult immunization in diverse primary care office settings. Vaccine. 2004;22(25-26):3457–63.CrossRefPubMed Nowalk MP, Zimmerman RK, Feghali J. Missed opportunities for adult immunization in diverse primary care office settings. Vaccine. 2004;22(25-26):3457–63.CrossRefPubMed
23.
go back to reference Nowalk MP, Zimmerman RK, Cleary SM, Bruehlman RD. Missed opportunities to vaccinate older adults in primary care. J Am Board Fam Pract. 2005;18(1):20–7.CrossRefPubMed Nowalk MP, Zimmerman RK, Cleary SM, Bruehlman RD. Missed opportunities to vaccinate older adults in primary care. J Am Board Fam Pract. 2005;18(1):20–7.CrossRefPubMed
24.
go back to reference Djibo DA, Peddecord KM, Wang W, Ralston K, Sawyer MH. Factors associated with missed opportunities for influenza vaccination review of medical records in a diverse sample of primary care clinics, San Diego County, 2010-2011. J Prim Care Community Health. 2015;6(3):147–53.CrossRefPubMed Djibo DA, Peddecord KM, Wang W, Ralston K, Sawyer MH. Factors associated with missed opportunities for influenza vaccination review of medical records in a diverse sample of primary care clinics, San Diego County, 2010-2011. J Prim Care Community Health. 2015;6(3):147–53.CrossRefPubMed
25.
go back to reference Lu P-j, O'Halloran A, Ding H, Srivastav A, Williams WW. Uptake of influenza vaccination and missed opportunities among adults with high-risk conditions, United States, 2013. Am J Med. 2016;129(6):636. e631–11.CrossRef Lu P-j, O'Halloran A, Ding H, Srivastav A, Williams WW. Uptake of influenza vaccination and missed opportunities among adults with high-risk conditions, United States, 2013. Am J Med. 2016;129(6):636. e631–11.CrossRef
26.
go back to reference Stone EG, Morton SC, Hulscher ME, Maglione MA, Roth EA, Grimshaw JM, Mittman BS, Rubenstein LV, Rubenstein LZ, Shekelle PG. Interventions that increase use of adult immunization and cancer screening services: a meta-analysis. Ann Intern Med. 2002;136(9):641–51.CrossRefPubMed Stone EG, Morton SC, Hulscher ME, Maglione MA, Roth EA, Grimshaw JM, Mittman BS, Rubenstein LV, Rubenstein LZ, Shekelle PG. Interventions that increase use of adult immunization and cancer screening services: a meta-analysis. Ann Intern Med. 2002;136(9):641–51.CrossRefPubMed
27.
go back to reference Pavlik VN, Chan W, Hyman DJ, Feldman P, Ogedegbe G, Schwartz JE, McDonald M, Einhorn P, Tobin JN. Designing and evaluating health systems level hypertension control interventions for African-Americans: lessons from a pooled analysis of three cluster randomized trials. Curr Hypertens Rev. 2015;11(2):123–31.CrossRefPubMedPubMedCentral Pavlik VN, Chan W, Hyman DJ, Feldman P, Ogedegbe G, Schwartz JE, McDonald M, Einhorn P, Tobin JN. Designing and evaluating health systems level hypertension control interventions for African-Americans: lessons from a pooled analysis of three cluster randomized trials. Curr Hypertens Rev. 2015;11(2):123–31.CrossRefPubMedPubMedCentral
Metadata
Title
Using the 4 pillars™ practice transformation program to increase adult influenza vaccination and reduce missed opportunities in a randomized cluster trial
Authors
Chyongchiou J. Lin
Mary Patricia Nowalk
Valory N. Pavlik
Anthony E. Brown
Song Zhang
Jonathan M. Raviotta
Krissy K. Moehling
Mary Hawk
Edmund M. Ricci
Donald B. Middleton
Suchita Patel
Jeannette E. South-Paul
Richard K. Zimmerman
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2016
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-016-1940-1

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