Skip to main content
Top
Published in: BMC Infectious Diseases 1/2016

Open Access 01-12-2016 | Case report

Effusive-constrictive pericarditis, hepatitis, and pancreatitis in a patient with possible coxsackievirus B infection: a case report

Authors: Jon Persichino, Roger Garrison, Rajagopal Krishnan, Made Sutjita

Published in: BMC Infectious Diseases | Issue 1/2016

Login to get access

Abstract

Background

Coxsackie B is a viral pathogen that presents with various invasive diseases in adults. Historically, the majority of adult cases with pericarditis or myocarditis have been attributed to coxsackievirus B. The presentation of this viral infection causing effusive-constrictive pericarditis, hepatitis or pancreatitis is rare. This case report is the first to describe a patient with concomitant effusive-constrictive pericarditis, hepatitis and pancreatitis from possible coxsackievirus B infection.

Case presentation

A 26-year old female was admitted to our hospital with the diagnosis of effusive-constrictive pericarditis complicated by tamponade and cardiac arrest. An emergent pericardiocentesis was performed successfully. Hepatitis and pancreatitis were also identified in our patient. After an extensive workup, coxsackievirus B infection was suspected by positive serum complement fixation antibody titers. Our patient made a full recovery and was discharged from the hospital.

Conclusion

Clinical suspicion of effusive-constrictive pericarditis with tamponade from coxsackievirus B should be considered in patients presenting with chest pain, dyspnea, jugular venous distention, hypotension, ST segment elevation on electrocardiogram, and ventricular interdependence with septal shift during diastole on transthoracic echocardiogram. Initial diagnoses of effusive-constrictive pericarditis resembling cardiac tamponade, hepatitis and pancreatitis can be challenging, and this case highlights the need for healthcare professionals to be cognizant of the association between these unusual clinical presentations and coxsackievirus B infection.
Appendix
Available only for authorised users
Literature
1.
go back to reference Romero JR, Modlin JF. Coxsackie viruses, Echoviruses, and numbered Enteroviruses. In: Bennett JE, Dolin R, Blaser MJ, editors. Mandell, Douglas and Bennett’s Principle and Practice of Infectious Diseases. New York: Elsevier; 2014. p. 8,062–8116. Romero JR, Modlin JF. Coxsackie viruses, Echoviruses, and numbered Enteroviruses. In: Bennett JE, Dolin R, Blaser MJ, editors. Mandell, Douglas and Bennett’s Principle and Practice of Infectious Diseases. New York: Elsevier; 2014. p. 8,062–8116.
2.
go back to reference Knowlton KU, Narezkina A, Savoia MC, Oxman MN. Myocarditis and Pericarditis. In: Bennett JE, Dolin R, Blaser MJ, editors. Mandell, Douglas and Bennett’s Principle and Practice of Infectious Diseases. New York: Elsevier; 2014. p. 1066–79. Knowlton KU, Narezkina A, Savoia MC, Oxman MN. Myocarditis and Pericarditis. In: Bennett JE, Dolin R, Blaser MJ, editors. Mandell, Douglas and Bennett’s Principle and Practice of Infectious Diseases. New York: Elsevier; 2014. p. 1066–79.
3.
go back to reference Saikia UN, Mishra B, Sharma M, Nada R, Radotra B. Disseminated coxsackievirus B fulminant myocarditis in an immunosuppressed adult: a case report. Diagn Microbiol Infect Dis. 2014;78:98–100.CrossRefPubMed Saikia UN, Mishra B, Sharma M, Nada R, Radotra B. Disseminated coxsackievirus B fulminant myocarditis in an immunosuppressed adult: a case report. Diagn Microbiol Infect Dis. 2014;78:98–100.CrossRefPubMed
4.
go back to reference Liapounova NA, Mouquet F, Ennezat PV. Acute myocardial infarction spurred by myopericarditis in a young female patient: Coxsackie B2 to blame. Acta Cardiol. 2011;66:79–81.PubMed Liapounova NA, Mouquet F, Ennezat PV. Acute myocardial infarction spurred by myopericarditis in a young female patient: Coxsackie B2 to blame. Acta Cardiol. 2011;66:79–81.PubMed
5.
go back to reference Zaheeruddin S, Bade NA, Jani S, Srichai MB. A case of coxsackie B virus infection leading to multi-organ inflammation: Myopericarditis and acute liver failure. Case Rep Intern Med. 2014;1:45–50. Zaheeruddin S, Bade NA, Jani S, Srichai MB. A case of coxsackie B virus infection leading to multi-organ inflammation: Myopericarditis and acute liver failure. Case Rep Intern Med. 2014;1:45–50.
6.
go back to reference Imazio M, Gaita F, LeWinter M. Evaluation and Treatment of Pericarditis. JAMA. 2015;314:1498–505.CrossRefPubMed Imazio M, Gaita F, LeWinter M. Evaluation and Treatment of Pericarditis. JAMA. 2015;314:1498–505.CrossRefPubMed
7.
go back to reference Delic D, Nesic Z, Prostran M, Simonovic J, Jankovic S. Anicteric hepatitis in an adult associated with coxsackie b4 virus infection. Infection. 2006;34:236–7.CrossRefPubMed Delic D, Nesic Z, Prostran M, Simonovic J, Jankovic S. Anicteric hepatitis in an adult associated with coxsackie b4 virus infection. Infection. 2006;34:236–7.CrossRefPubMed
8.
go back to reference David JJ, Dietz FR, Jones MM. Coxsackie-B monoarthritis with hepatitis: A case report. J Bone Joint Surg Am. 1993;75:1685–6.PubMed David JJ, Dietz FR, Jones MM. Coxsackie-B monoarthritis with hepatitis: A case report. J Bone Joint Surg Am. 1993;75:1685–6.PubMed
9.
go back to reference Ozsvar Z, Deak J, Pap A. Possible role of Coxsackie-B virus infection in pancreatitis. Int J Pancreatol. 1992;11:105–8.PubMed Ozsvar Z, Deak J, Pap A. Possible role of Coxsackie-B virus infection in pancreatitis. Int J Pancreatol. 1992;11:105–8.PubMed
10.
go back to reference Lal SM, Fowler D, Lossasso CJ, Berg GG. Coxsackie virus-induced acute pancreatitis in a long-term dialysis patient. Am J Kidney Dis. 1988;11:434–6.CrossRefPubMed Lal SM, Fowler D, Lossasso CJ, Berg GG. Coxsackie virus-induced acute pancreatitis in a long-term dialysis patient. Am J Kidney Dis. 1988;11:434–6.CrossRefPubMed
11.
go back to reference Chrysos G, Kokkoris S, Protopsaltis J, Korantzopoulos, Giannoulis G. Coxsackie Infection Associated with Acute Pancreatitis. J Pancreas. 2004;5:384–7. Chrysos G, Kokkoris S, Protopsaltis J, Korantzopoulos, Giannoulis G. Coxsackie Infection Associated with Acute Pancreatitis. J Pancreas. 2004;5:384–7.
12.
go back to reference Sagrista-Sauleda J, Angel J, Sanchez A, Permanyer-Miralda G, Soler-Soler J. Effusive-constrictive pericarditis. N Engl J Med. 2004;350:469–75.CrossRefPubMed Sagrista-Sauleda J, Angel J, Sanchez A, Permanyer-Miralda G, Soler-Soler J. Effusive-constrictive pericarditis. N Engl J Med. 2004;350:469–75.CrossRefPubMed
13.
go back to reference Lee WS, Lee KJ, Kwon JE, Oh MS, Kim JE, Cho EJ, Kim CJ. Acute viral myopericarditis presenting as a transient effusive-constrictive pericarditis caused by coinfection with coxsackieviruses A4 and B3. Korean J Intern Med. 2012;27:216–20.CrossRefPubMedPubMedCentral Lee WS, Lee KJ, Kwon JE, Oh MS, Kim JE, Cho EJ, Kim CJ. Acute viral myopericarditis presenting as a transient effusive-constrictive pericarditis caused by coinfection with coxsackieviruses A4 and B3. Korean J Intern Med. 2012;27:216–20.CrossRefPubMedPubMedCentral
15.
go back to reference Coplan NL, Atallah V, Mediratta S, Bruno MS, DePasquale NP. Cardiac, pancreatic and liver abnormalities in a patient with coxsackie-B infection. Am J Med. 1996;101:325–6.CrossRefPubMed Coplan NL, Atallah V, Mediratta S, Bruno MS, DePasquale NP. Cardiac, pancreatic and liver abnormalities in a patient with coxsackie-B infection. Am J Med. 1996;101:325–6.CrossRefPubMed
Metadata
Title
Effusive-constrictive pericarditis, hepatitis, and pancreatitis in a patient with possible coxsackievirus B infection: a case report
Authors
Jon Persichino
Roger Garrison
Rajagopal Krishnan
Made Sutjita
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2016
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-016-1752-3

Other articles of this Issue 1/2016

BMC Infectious Diseases 1/2016 Go to the issue