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Published in: BMC Geriatrics 1/2020

Open Access 01-12-2020 | Public Health | Research article

Long-term cost-utility analysis of remote monitoring of older patients with pacemakers: the PONIENTE study

Authors: Rafael Jesus Bautista-Mesa, Antonio Lopez-Villegas, Salvador Peiro, Daniel Catalan-Matamoros, Emilio Robles-Musso, Remedios Lopez-Liria, Cesar Leal-Costa

Published in: BMC Geriatrics | Issue 1/2020

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Abstract

Background

Cost-effectiveness studies on pacemakers have increased in the last years. However the number of long-term cost-utility studies is limited. The objective of this study was to perform a cost-utility analysis comparing remote monitoring (RM) versus conventional monitoring (CM) in hospital of older patients with pacemakers, 5 years after implant.

Methods

Under a controlled, not randomized, nor masked clinical trial, 83 patients with pacemakers were initially selected. After five years of follow-up, a total of 55 patients (CM = 34; RM = 21) completed the study. A cost-utility analysis of RM in terms of costs per gained quality-adjusted life years (QALYs) was conducted. The costs from the Public Health System (PHS) as well as patients and their relatives were taken into account for the study. The robustness of the results was verified by the probabilistic analyses through Monte-Carlo simulations.

Results

After a five-year follow-up period, total costs were lower in the RM group by 23.02% than in the CM group (€274.52 versus €356.62; p = 0.033) because of a cost saving from patients’ perspective (€59.05 versus €102.98; p = 0.002). However, the reduction of in-hospital visits derived from RM exhibited insignificant impact on the costs from the PHS perspective, with a cost saving of 15.04% (€215.48 vs. €253.64; p = 0.144). Costs/QALYs obtained by the RM group were higher as compared to the CM group, although there were no significant differences. The incremental cost-effectiveness ratio of CM in comparison to RM became positive (€301.16).

Conclusions

This study confirms RM of older patients with pacemakers appears still as a cost-utility alternative to CM in hospital after 5 years of follow-up.

Trial registration

ClinicalTrials.gov: (Identifier: NCT02234245). Registered 09 September 2014 - Prospectively registered.
Literature
1.
go back to reference Wilkoff BL, Auricchio A, Brugada J, Cowie M, Ellenbogen KA, Gillis AM, Hayes DL, Howlett JG, Kautzner J, Love CJ, Morgan JM, Priori SG, Reynolds DW, Schoenfeld MH, Vardas PE, Heart Rhythm Society (HRS); European Heart Rhythm Association (EHRA); American College of Cardiology (ACC); American Heart Association (AHA); European Society of Cardiology (ESC); Heart Failure Association of ESC (HFA); Heart Failure Society of America (HFSA). HRS/EHRA Expert Consensus on the Monitoring of Cardiovascular Implantable Electronic Devices (CIEDs): description of techniques, indications, personnel, frequency and ethical considerations: developed in partnership with the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA); and in collaboration with the American College of Cardiology (ACC), the American Heart Association (AHA), the European Society of Cardiology (ESC), the Heart Failure Association of ESC (HFA), and the Heart Failure Society of America (HFSA). Endorsed by the Heart Rhythm Society, the European Heart Rhythm Association (a registered branch of the ESC), the American College of Cardiology, the American Heart Association. Europace. 2008 Jun;10(6):707–25.PubMedCrossRef Wilkoff BL, Auricchio A, Brugada J, Cowie M, Ellenbogen KA, Gillis AM, Hayes DL, Howlett JG, Kautzner J, Love CJ, Morgan JM, Priori SG, Reynolds DW, Schoenfeld MH, Vardas PE, Heart Rhythm Society (HRS); European Heart Rhythm Association (EHRA); American College of Cardiology (ACC); American Heart Association (AHA); European Society of Cardiology (ESC); Heart Failure Association of ESC (HFA); Heart Failure Society of America (HFSA). HRS/EHRA Expert Consensus on the Monitoring of Cardiovascular Implantable Electronic Devices (CIEDs): description of techniques, indications, personnel, frequency and ethical considerations: developed in partnership with the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA); and in collaboration with the American College of Cardiology (ACC), the American Heart Association (AHA), the European Society of Cardiology (ESC), the Heart Failure Association of ESC (HFA), and the Heart Failure Society of America (HFSA). Endorsed by the Heart Rhythm Society, the European Heart Rhythm Association (a registered branch of the ESC), the American College of Cardiology, the American Heart Association. Europace. 2008 Jun;10(6):707–25.PubMedCrossRef
2.
go back to reference Cronin E, Varma N. Remote monitoring of cardiovascular implanted electronic devices: a paradigm shift for the 21st century. Expert Rev Med Devices. 2012;9(4):367–76.PubMedCrossRef Cronin E, Varma N. Remote monitoring of cardiovascular implanted electronic devices: a paradigm shift for the 21st century. Expert Rev Med Devices. 2012;9(4):367–76.PubMedCrossRef
3.
go back to reference Mabo P, Victor F, Bazin P, Ahres S, Babuty D, Da Costa A, Binet D, Dauber J C.t. A randomized trial of long-term remote monitoring of pacemaker recipients (The COMPAS trial). European Heart Journal 2012; 33: 1105–1111. Mabo P, Victor F, Bazin P, Ahres S, Babuty D, Da Costa A, Binet D, Dauber J C.t. A randomized trial of long-term remote monitoring of pacemaker recipients (The COMPAS trial). European Heart Journal 2012; 33: 1105–1111.
4.
go back to reference Amala A, Turner T, Gretton M, Baksh A, Cleland J. A systematic review of telemonitoring for the management of heart failure. European Journal of Heart Failure. 2003;5:583–90.CrossRef Amala A, Turner T, Gretton M, Baksh A, Cleland J. A systematic review of telemonitoring for the management of heart failure. European Journal of Heart Failure. 2003;5:583–90.CrossRef
5.
go back to reference Folino AF, Breda R, Calzavara P, Migliore F, Iliceto S, Buja G. In-home controls of pacemakers in debilitated elderly patients. Geriatrics and gerontology international. 2012;12:30–5.PubMedCrossRef Folino AF, Breda R, Calzavara P, Migliore F, Iliceto S, Buja G. In-home controls of pacemakers in debilitated elderly patients. Geriatrics and gerontology international. 2012;12:30–5.PubMedCrossRef
6.
go back to reference López-Villegas A, Catalán-Matamoros D, Robles-Musso E, Peiró S. Comparative effectiveness of remote monitoring of people with cardiac Pacemaker versus conventional: Quality of life at the 6 months. Revista Española de Salud Pública. 2015;89(2):149–58.PubMedCrossRef López-Villegas A, Catalán-Matamoros D, Robles-Musso E, Peiró S. Comparative effectiveness of remote monitoring of people with cardiac Pacemaker versus conventional: Quality of life at the 6 months. Revista Española de Salud Pública. 2015;89(2):149–58.PubMedCrossRef
7.
go back to reference López-Villegas A, Catalán-Matamoros D, Robles-Musso E, Peiró S. Effectiveness of Pacemaker Tele-Monitoring on Quality of Life, Functional Capacity, Event Detection and Workload. The PONIENTE trial. Geriatrics and Gerontology International. 2016;16(11):1188–95.PubMedCrossRef López-Villegas A, Catalán-Matamoros D, Robles-Musso E, Peiró S. Effectiveness of Pacemaker Tele-Monitoring on Quality of Life, Functional Capacity, Event Detection and Workload. The PONIENTE trial. Geriatrics and Gerontology International. 2016;16(11):1188–95.PubMedCrossRef
8.
go back to reference Ricci RP, Morichelli L, Santini M. Home monitoring remote control of pacemaker and implantable cardioverter defibrillator patients in clinical practice: impact on medical management and health-care resource utilization. Europace. 2008;10:164–70.PubMedCrossRef Ricci RP, Morichelli L, Santini M. Home monitoring remote control of pacemaker and implantable cardioverter defibrillator patients in clinical practice: impact on medical management and health-care resource utilization. Europace. 2008;10:164–70.PubMedCrossRef
9.
go back to reference Guedon-Moreau L, Lacroix D, Sadoul N, Clementy J, Kouakam C, Hermida JS, Aliot E, Boursier M, Bizeau O, Kacet S, ECOST trial Investigators. A randomized study of remote follow-up of implantable cardioverter defibrillators: safety and efficacy report of the ECOST trial. European Heart Journal. 2013;34:605–14.PubMedCrossRef Guedon-Moreau L, Lacroix D, Sadoul N, Clementy J, Kouakam C, Hermida JS, Aliot E, Boursier M, Bizeau O, Kacet S, ECOST trial Investigators. A randomized study of remote follow-up of implantable cardioverter defibrillators: safety and efficacy report of the ECOST trial. European Heart Journal. 2013;34:605–14.PubMedCrossRef
10.
go back to reference Halimi F, Clémenty J, Attuel P, Dessenne X, Amara W, on behalf of the OEDIPE trial Investigators. Optimized post-operative surveillance of permanent pacemakers by home monitoring: the OEDIPE trial. Europace. 2008;10:1392–9.PubMedPubMedCentralCrossRef Halimi F, Clémenty J, Attuel P, Dessenne X, Amara W, on behalf of the OEDIPE trial Investigators. Optimized post-operative surveillance of permanent pacemakers by home monitoring: the OEDIPE trial. Europace. 2008;10:1392–9.PubMedPubMedCentralCrossRef
11.
go back to reference García-Fernández FJ, Osca Asensi J, Romero R, Fernández Lozano I, Larrazabal JM, Martínez Ferrer J, Ortiz R, Pombo M, Tornés FJ, Moradi Kolbolandi M. Safety and efficiency of a common and simplified protocol for pacemaker and defibrillator surveillance based on remote monitoring only: a long-term randomized trial (RM-ALONE). European Heart Journal. 2019;40(23):1837–46.PubMedPubMedCentralCrossRef García-Fernández FJ, Osca Asensi J, Romero R, Fernández Lozano I, Larrazabal JM, Martínez Ferrer J, Ortiz R, Pombo M, Tornés FJ, Moradi Kolbolandi M. Safety and efficiency of a common and simplified protocol for pacemaker and defibrillator surveillance based on remote monitoring only: a long-term randomized trial (RM-ALONE). European Heart Journal. 2019;40(23):1837–46.PubMedPubMedCentralCrossRef
12.
go back to reference Barlow J, Bayer S, Curry R. Implementing complex innovations in fluid multi-stakeholder environments: Experiences of “telecare”. Technovation. 2006;26:396–406.CrossRef Barlow J, Bayer S, Curry R. Implementing complex innovations in fluid multi-stakeholder environments: Experiences of “telecare”. Technovation. 2006;26:396–406.CrossRef
13.
go back to reference Christensen J. The emergence and unfolding of telemonitoring practices in different healthcare organizations. International journal of environmental research and public health. 2018;15(1):61.PubMedCentralCrossRef Christensen J. The emergence and unfolding of telemonitoring practices in different healthcare organizations. International journal of environmental research and public health. 2018;15(1):61.PubMedCentralCrossRef
14.
go back to reference Zanaboni P, Landolina M, Marzegalli M, Lunati M, Perego GB, Guenzati G, Curnis A, Valsecchi S, Borghetti F, Borghi G, Masella C. Cost-utility analysis of the EVOLVO study on remote monitoring for heart failure patients with implantable defibrillators: randomized controlled trial. Journal of medical Internet research. 2013;15(5):106.CrossRef Zanaboni P, Landolina M, Marzegalli M, Lunati M, Perego GB, Guenzati G, Curnis A, Valsecchi S, Borghetti F, Borghi G, Masella C. Cost-utility analysis of the EVOLVO study on remote monitoring for heart failure patients with implantable defibrillators: randomized controlled trial. Journal of medical Internet research. 2013;15(5):106.CrossRef
15.
go back to reference Halimi F, Cantu F. Remote monitoring for active cardiovascular implantable electronic devices: a European survey. Europace. 2010;12:1778–80.PubMedCrossRef Halimi F, Cantu F. Remote monitoring for active cardiovascular implantable electronic devices: a European survey. Europace. 2010;12:1778–80.PubMedCrossRef
17.
go back to reference Haugaa KH, Potpara TS, Boveda S, Deharo JC, Chen J, Dobreanu D, Sciarrafia E. Patients’ knowledge and attitudes regarding living with implantable electronic devices: results of a multicentre, multinational patient survey conducted by the European Heart Rhythm Association. Ep Europace. 2017;20(2):386–91.CrossRef Haugaa KH, Potpara TS, Boveda S, Deharo JC, Chen J, Dobreanu D, Sciarrafia E. Patients’ knowledge and attitudes regarding living with implantable electronic devices: results of a multicentre, multinational patient survey conducted by the European Heart Rhythm Association. Ep Europace. 2017;20(2):386–91.CrossRef
18.
go back to reference Somat A. Acceptabilité, acceptabilité sociale des systèmes technologiques : ingénierie de la notion d’usage. Grenoble: Conférence des sciences de l’éducation, Université Pierre-Mendès-France; 2008. Somat A. Acceptabilité, acceptabilité sociale des systèmes technologiques : ingénierie de la notion d’usage. Grenoble: Conférence des sciences de l’éducation, Université Pierre-Mendès-France; 2008.
19.
go back to reference Poder TG, Bellemare CA, Bédard SK, Lemieux R. Social acceptance and population confidence in telehealth in Quebec. BMC Health Services Research. 2015;15:72.PubMedPubMedCentralCrossRef Poder TG, Bellemare CA, Bédard SK, Lemieux R. Social acceptance and population confidence in telehealth in Quebec. BMC Health Services Research. 2015;15:72.PubMedPubMedCentralCrossRef
20.
go back to reference Winkelmayer WC, Cohen DJ, Berger ML, Neumann PJ. Comparing cost-utility analyses in cardiovascular medicine. In: Weintraub WS, editor. Cardiovascular Health Care Economics. Totowa: Humana Press; 2003. p. 329–56.CrossRef Winkelmayer WC, Cohen DJ, Berger ML, Neumann PJ. Comparing cost-utility analyses in cardiovascular medicine. In: Weintraub WS, editor. Cardiovascular Health Care Economics. Totowa: Humana Press; 2003. p. 329–56.CrossRef
21.
go back to reference Burri H, Sticherling C, Wright D, Makino K, Smala A, Tilden D. Cost-consequence analysis of daily continuous remote monitoring of implantable cardiac defibrillator and resynchronization devices in the UK. Europace. 2013;15(11):1601–8.PubMedPubMedCentralCrossRef Burri H, Sticherling C, Wright D, Makino K, Smala A, Tilden D. Cost-consequence analysis of daily continuous remote monitoring of implantable cardiac defibrillator and resynchronization devices in the UK. Europace. 2013;15(11):1601–8.PubMedPubMedCentralCrossRef
22.
go back to reference Urquhart AC, Antoniotti NM, Berg RL. Telemedicine – an efficient and cost-effective approach in parathyroid surgery. Laryngoscope. 2011;121(7):1422–5.PubMedCrossRef Urquhart AC, Antoniotti NM, Berg RL. Telemedicine – an efficient and cost-effective approach in parathyroid surgery. Laryngoscope. 2011;121(7):1422–5.PubMedCrossRef
23.
go back to reference Capucci A, De Simone A, Luzi M, Calvi V, Stabile G, D'Onofrio A, Maffei S, Leoni L, Morani G, Sangiuolo R, Amellone C, Checchinato C, Ammendola E, Buja G. Economic impact of remote monitoring after implantable defibrillators implantation in heart failure patients: an analysis from the EFFECT study. Europace. 2017 Sep 1;19(9):1493–9.PubMedCrossRef Capucci A, De Simone A, Luzi M, Calvi V, Stabile G, D'Onofrio A, Maffei S, Leoni L, Morani G, Sangiuolo R, Amellone C, Checchinato C, Ammendola E, Buja G. Economic impact of remote monitoring after implantable defibrillators implantation in heart failure patients: an analysis from the EFFECT study. Europace. 2017 Sep 1;19(9):1493–9.PubMedCrossRef
24.
go back to reference Dario C, Delise P, Gubian L, Saccavini C, Brandolino G, Mancin S. Large controlled observational study on remote monitoring of pacemakers and implantable cardiac defibrillators: a clinical, economic, and organizational evaluation. Interact J Med Res. 2016;5(1):4.CrossRef Dario C, Delise P, Gubian L, Saccavini C, Brandolino G, Mancin S. Large controlled observational study on remote monitoring of pacemakers and implantable cardiac defibrillators: a clinical, economic, and organizational evaluation. Interact J Med Res. 2016;5(1):4.CrossRef
25.
go back to reference Raatikainen MJ, Uusimaa P, van Ginneken MM, Janssen JP, Linnaluoto M. Remote monitoring of implantable cardioverter defibrillator patients: a safe, time-saving, and cost-effective means for follow-up. Europace. 2008;10(10):1145–51.PubMedPubMedCentralCrossRef Raatikainen MJ, Uusimaa P, van Ginneken MM, Janssen JP, Linnaluoto M. Remote monitoring of implantable cardioverter defibrillator patients: a safe, time-saving, and cost-effective means for follow-up. Europace. 2008;10(10):1145–51.PubMedPubMedCentralCrossRef
26.
go back to reference Hofmann R, Voller H, Nagels K, et al. First outline and baseline data of a randomized, controlled multicenter trial to evaluate the health economic impact of home telemonitoring in chronic heart failure – CardioBBEAT. Trials. 2015;16:343.PubMedPubMedCentralCrossRef Hofmann R, Voller H, Nagels K, et al. First outline and baseline data of a randomized, controlled multicenter trial to evaluate the health economic impact of home telemonitoring in chronic heart failure – CardioBBEAT. Trials. 2015;16:343.PubMedPubMedCentralCrossRef
27.
go back to reference Perl S, Stiegler P, Rotman B, Prenner G, Lercher P, Anelli-Monti M, Sereinigg M, Riegelnik V, Kvas E, Kos C, Heinzel FR, Tscheliessnigg KH, Pieske B. Socio-economic effects and cost saving potential of remote patient monitoring (SAVE-HM trial). International Journal of Cardiology. 2013;169:402–7.PubMedCrossRef Perl S, Stiegler P, Rotman B, Prenner G, Lercher P, Anelli-Monti M, Sereinigg M, Riegelnik V, Kvas E, Kos C, Heinzel FR, Tscheliessnigg KH, Pieske B. Socio-economic effects and cost saving potential of remote patient monitoring (SAVE-HM trial). International Journal of Cardiology. 2013;169:402–7.PubMedCrossRef
28.
go back to reference López-Villegas A, Catalán-Matamoros D, Martín-Saborido C, Villegas Tripiana I, Robles-Musso E. A Systematic Review of Economic Evaluations of Pacemaker Telemonitoring Systems. Revista Española de Cardiología. 2016;69(2):125–33.PubMedCrossRef López-Villegas A, Catalán-Matamoros D, Martín-Saborido C, Villegas Tripiana I, Robles-Musso E. A Systematic Review of Economic Evaluations of Pacemaker Telemonitoring Systems. Revista Española de Cardiología. 2016;69(2):125–33.PubMedCrossRef
29.
go back to reference Lopez-Villegas A, Catalan-Matamoros D, Peiro S, Lappegard K, Lopez-Liria R. Cost–utility analysis of telemonitoring versus conventional hospital-based follow-up of patients with pacemakers. The NORDLAND randomized clinical trial. PLoS ONE. 2020;15(1):e0226188.PubMedPubMedCentralCrossRef Lopez-Villegas A, Catalan-Matamoros D, Peiro S, Lappegard K, Lopez-Liria R. Cost–utility analysis of telemonitoring versus conventional hospital-based follow-up of patients with pacemakers. The NORDLAND randomized clinical trial. PLoS ONE. 2020;15(1):e0226188.PubMedPubMedCentralCrossRef
30.
go back to reference Lopez-Villegas A, Catalan-Matamoros D, Robles-Musso E, Bautista-Mesa R, Peiro S. Cost-utility analysis on telemonitoring of users with pacemakers: The PONIENTE study. Journal of Telemedicine and Telecare. 2019;25(4):204–12.PubMedCrossRef Lopez-Villegas A, Catalan-Matamoros D, Robles-Musso E, Bautista-Mesa R, Peiro S. Cost-utility analysis on telemonitoring of users with pacemakers: The PONIENTE study. Journal of Telemedicine and Telecare. 2019;25(4):204–12.PubMedCrossRef
36.
go back to reference Badia X, Roset M, Montserrat S, Herdman M, Segura A. La versión española del EuroQol: descripción y aplicaciones. Medicina Clínica. 1999;112(Supl 1):79–86.PubMed Badia X, Roset M, Montserrat S, Herdman M, Segura A. La versión española del EuroQol: descripción y aplicaciones. Medicina Clínica. 1999;112(Supl 1):79–86.PubMed
37.
go back to reference EuroQol Group. EuroQol . A new facility for the measurement of health-related quality of life. Health Policy. 1990;16:199–208.CrossRef EuroQol Group. EuroQol . A new facility for the measurement of health-related quality of life. Health Policy. 1990;16:199–208.CrossRef
38.
go back to reference Drummond MF, Sculpher MJ, Torrance GW, O'Brien BJ, Stoddart GL. Methods for the Economic Evaluation of Health Care Programmes. 3rd ed. New York, NY: Oxford University Press; 2005. Drummond MF, Sculpher MJ, Torrance GW, O'Brien BJ, Stoddart GL. Methods for the Economic Evaluation of Health Care Programmes. 3rd ed. New York, NY: Oxford University Press; 2005.
39.
go back to reference Gold MR, Siegel JE, Russell LB, Weinstein MC. Cost-Effectiveness in Health and Medicine. New York, NY: Oxford University Press; 1996. Gold MR, Siegel JE, Russell LB, Weinstein MC. Cost-Effectiveness in Health and Medicine. New York, NY: Oxford University Press; 1996.
40.
go back to reference Altawalbeh SM, Alshogran OY, Smith KJ. Cost-Utility Analysis of Apixaban versus Warfarin in Atrial Fibrillation Patients with Chronic Kidney Disease. Value in Health. 2018;21(12):1365–72.PubMedCrossRef Altawalbeh SM, Alshogran OY, Smith KJ. Cost-Utility Analysis of Apixaban versus Warfarin in Atrial Fibrillation Patients with Chronic Kidney Disease. Value in Health. 2018;21(12):1365–72.PubMedCrossRef
41.
go back to reference Crossley GH, Boyle A, Vitense A, Chang Y. Mead RH for the CONNECT Investigators, The CONNECT (Clinical Evaluation of Remote Notification to Reduce Time to Clinical Decision) Trial: The value of wireless remote monitoring with automatic clinician alerts. Journal of the American College of Cardiology. 2011;57:1182–9.CrossRef Crossley GH, Boyle A, Vitense A, Chang Y. Mead RH for the CONNECT Investigators, The CONNECT (Clinical Evaluation of Remote Notification to Reduce Time to Clinical Decision) Trial: The value of wireless remote monitoring with automatic clinician alerts. Journal of the American College of Cardiology. 2011;57:1182–9.CrossRef
42.
go back to reference Lopez-Villegas A, Catalan-Matamoros D, Lopez-Liria R, Enebakk T, Thunhaug H, Lappegård KT. Health-related quality of life on tele-monitoring for users with pacemakers 6 months after implant: the NORDLAND study, a randomized trial. BMC Geriatr. 2018;18(1):223.PubMedPubMedCentralCrossRef Lopez-Villegas A, Catalan-Matamoros D, Lopez-Liria R, Enebakk T, Thunhaug H, Lappegård KT. Health-related quality of life on tele-monitoring for users with pacemakers 6 months after implant: the NORDLAND study, a randomized trial. BMC Geriatr. 2018;18(1):223.PubMedPubMedCentralCrossRef
43.
go back to reference Folino A, Breda R, Calzavara P, Borghetti F, Comisso J, Iliceto S, Buja G. Remote follow-up of pacemakers in a selected population of debilitated elderly patients. Europace. 2013;15(3):382–7.PubMedCrossRef Folino A, Breda R, Calzavara P, Borghetti F, Comisso J, Iliceto S, Buja G. Remote follow-up of pacemakers in a selected population of debilitated elderly patients. Europace. 2013;15(3):382–7.PubMedCrossRef
44.
go back to reference Morgan JM, Kitt S, Gill J, McComb JM, Ng GA, Raftery J, Roderick P, Seed A, Williams SG, Witte KK, Wright DJ, Harris S, Cowie MR. Remote management of heart failure using implantable electronic devices. European Heart Journal. 2017;38(30):2352–60.PubMedPubMedCentralCrossRef Morgan JM, Kitt S, Gill J, McComb JM, Ng GA, Raftery J, Roderick P, Seed A, Williams SG, Witte KK, Wright DJ, Harris S, Cowie MR. Remote management of heart failure using implantable electronic devices. European Heart Journal. 2017;38(30):2352–60.PubMedPubMedCentralCrossRef
45.
go back to reference Boriani G, Da Costa A, Quesada A, Ricci RP, Favale S, Boscolo G, Clementy N, Amori V, Mangoni di S Stefano L, Burri H; MORE-CARE Study Investigators. Effects of remote monitoring on clinical outcomes and use of healthcare resources in heart failure patients with biventricular defibrillators: results of the MORE-CARE multicentre randomized controlled trial. European Journal of Heart Failure. 2017;19 (3):416–425. Boriani G, Da Costa A, Quesada A, Ricci RP, Favale S, Boscolo G, Clementy N, Amori V, Mangoni di S Stefano L, Burri H; MORE-CARE Study Investigators. Effects of remote monitoring on clinical outcomes and use of healthcare resources in heart failure patients with biventricular defibrillators: results of the MORE-CARE multicentre randomized controlled trial. European Journal of Heart Failure. 2017;19 (3):416–425.
46.
go back to reference Freeman JV, Saxon L. Remote Monitoring and Outcomes in Pacemaker and Defibrillator Patients. Big Data Saving Lives? Journal of the American College of Cardiology. 2015 Jun 23;65(24):2611–3.PubMedCrossRef Freeman JV, Saxon L. Remote Monitoring and Outcomes in Pacemaker and Defibrillator Patients. Big Data Saving Lives? Journal of the American College of Cardiology. 2015 Jun 23;65(24):2611–3.PubMedCrossRef
47.
go back to reference Zabel M, Müller-Riemenschneider F, Christoph Geller FJ, Brachmann J, Kühlkamp V, Dissmann R, Reinhold T, Roll S, Lüthje L, Bode F, Eckardt L, Willich SN, investigators MONITOR-ICD. Rationale and design of the MONITOR-ICD study: A randomized comparison of economic and clinical effects of automatic remote monitoring versus control in patients with Implantable Cardioverter Defibrillators. American Heart Journal. 2014;168(4):430–7.PubMedCrossRef Zabel M, Müller-Riemenschneider F, Christoph Geller FJ, Brachmann J, Kühlkamp V, Dissmann R, Reinhold T, Roll S, Lüthje L, Bode F, Eckardt L, Willich SN, investigators MONITOR-ICD. Rationale and design of the MONITOR-ICD study: A randomized comparison of economic and clinical effects of automatic remote monitoring versus control in patients with Implantable Cardioverter Defibrillators. American Heart Journal. 2014;168(4):430–7.PubMedCrossRef
48.
go back to reference Neyt M, Stroobandt S, Obyn C, Camberlin C, Devriese S, De Laet C, Van Brabandt H. Cost-effectiveness of cardiac resynchronisation therapy for patients with moderate-to-severe heart failure: a lifetime Markov model. BMJ Open. 2011;1(2):e000276.PubMedPubMedCentralCrossRef Neyt M, Stroobandt S, Obyn C, Camberlin C, Devriese S, De Laet C, Van Brabandt H. Cost-effectiveness of cardiac resynchronisation therapy for patients with moderate-to-severe heart failure: a lifetime Markov model. BMJ Open. 2011;1(2):e000276.PubMedPubMedCentralCrossRef
49.
50.
go back to reference Koehler F, Koehler K, Deckwart O, Prescher S, Wegscheider K, Kirwan BA, Winkler S, Vettorazzi E, Bruch L, Oeff M, Zugck C, Doerr G, Naegele H, Störk S, Butter C, Sechtem U, Angermann C, Gola G, Prondzinsky R, Edelmann F, Spethmann S, Schellong SM, Schulze PC, Bauersachs J, Wellge B, Schoebel C, Tajsic M, Dreger H, Anker SD, Stangl K. Efficacy of telemedical interventional management in patients with heart failure (TIM-HF2): a randomised, controlled, parallel-group, unmasked trial. Lancet. 2018 Sep 22;392(10152):1047–57.PubMedCrossRef Koehler F, Koehler K, Deckwart O, Prescher S, Wegscheider K, Kirwan BA, Winkler S, Vettorazzi E, Bruch L, Oeff M, Zugck C, Doerr G, Naegele H, Störk S, Butter C, Sechtem U, Angermann C, Gola G, Prondzinsky R, Edelmann F, Spethmann S, Schellong SM, Schulze PC, Bauersachs J, Wellge B, Schoebel C, Tajsic M, Dreger H, Anker SD, Stangl K. Efficacy of telemedical interventional management in patients with heart failure (TIM-HF2): a randomised, controlled, parallel-group, unmasked trial. Lancet. 2018 Sep 22;392(10152):1047–57.PubMedCrossRef
51.
go back to reference Chang S, Davidson PM, Newton PJ, Macdonald P, Carrington MJ, Marwick TH, Horowitz JD, Krum H, Reid CM, Chan YK, Scuffham PA, Sibbritt D, Stewart S, Investigators WHICH. Composite outcome measures in a pragmatic clinical trial of chronic heart failure management: A comparative assessment. International Jorunal of Cardiology. 2015 Apr 15;185:62–8. https://doi.org/10.1016/j.ijcard.2015.03.071. Epub 2015 Mar 5 25791092. Chang S, Davidson PM, Newton PJ, Macdonald P, Carrington MJ, Marwick TH, Horowitz JD, Krum H, Reid CM, Chan YK, Scuffham PA, Sibbritt D, Stewart S, Investigators WHICH. Composite outcome measures in a pragmatic clinical trial of chronic heart failure management: A comparative assessment. International Jorunal of Cardiology. 2015 Apr 15;185:62–8. https://​doi.​org/​10.​1016/​j.​ijcard.​2015.​03.​071. Epub 2015 Mar 5 25791092.
52.
go back to reference Pocock SJ, Gersh BJ. Do current clinical trials meet society’s needs?: a critical review of recent evidence. J Am College Cardiology. 2014;64:1615–28.CrossRef Pocock SJ, Gersh BJ. Do current clinical trials meet society’s needs?: a critical review of recent evidence. J Am College Cardiology. 2014;64:1615–28.CrossRef
53.
go back to reference Cano Pérez O, Pombo Jiménez M, Lorente Carreño D, Chimeno García J. Spanish Pacemaker Registry. 16th Official Report of the Spanish Society of Cardiology Working Group on Cardiac Pacing (2018). Revista Española de Cardiología. 2019;72(11):944–53.PubMedCrossRef Cano Pérez O, Pombo Jiménez M, Lorente Carreño D, Chimeno García J. Spanish Pacemaker Registry. 16th Official Report of the Spanish Society of Cardiology Working Group on Cardiac Pacing (2018). Revista Española de Cardiología. 2019;72(11):944–53.PubMedCrossRef
Metadata
Title
Long-term cost-utility analysis of remote monitoring of older patients with pacemakers: the PONIENTE study
Authors
Rafael Jesus Bautista-Mesa
Antonio Lopez-Villegas
Salvador Peiro
Daniel Catalan-Matamoros
Emilio Robles-Musso
Remedios Lopez-Liria
Cesar Leal-Costa
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Geriatrics / Issue 1/2020
Electronic ISSN: 1471-2318
DOI
https://doi.org/10.1186/s12877-020-01883-3

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