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Open Access 01-12-2019 | Affective Disorder | Research article

Validity of a novel screen for cognitive impairment and neuropsychiatric symptoms in cardiac rehabilitation

Authors: Dana Mohammad, Nathan Herrmann, Mahwesh Saleem, Richard H. Swartz, Paul I. Oh, Janelle Bradley, Parco Chan, Courtney Ellis, Krista L. Lanctôt

Published in: BMC Geriatrics | Issue 1/2019

Abstract

Background

Currently, there is no composite screening tool that can efficiently and effectively assess prevalent yet under-recognized cognitive and neuropsychiatric comorbidities in patients with cardiovascular disease. We aimed to determine the validity and feasibility of a novel screen assessing cognitive impairment, anxiety, apathy and depression (CAAD screen) in those attending cardiac rehabilitation (CR).

Methods

All patients diagnosed with cardiovascular disease or cardiovascular risk factors entering CR were screened as part of clinical care. A subset of those patients agreed to complete validation assessments (n = 127). Screen results were compared to widely accepted standards for cognition, anxiety, apathy, and depression using a modified receiver operating characteristic (ROC) and area under the curve analysis.

Results

The screen was completed by 97% of participants in 10 min or less with an average completion time of approximately 5 min. Screening scores adjusted for age, sex and years of education had acceptable or excellent validity compared to widely accepted standard diagnoses: CAAD-Cog (AUC = 0.80); CAAD-Anx (AUC = 0.81); CAAD-Apathy (AUC = 0.79) and CAAD-Dep (AUC = 0.85).

Conclusions

The CAAD screen may be a valid and feasible tool for detecting cognitive impairment, anxiety, apathy and depression in CR settings.

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Title: Validity of a novel screen for cognitive impairment and neuropsychiatric symptoms in cardiac rehabilitation
Authors: Dana Mohammad
Nathan Herrmann
Mahwesh Saleem
Richard H. Swartz
Paul I. Oh
Janelle Bradley
Parco Chan
Courtney Ellis
Krista L. Lanctôt
Publication date: 01-12-2019
Publisher: BioMed Central
Keywords: Affective Disorder
Affective Disorder
Anxiety
Published in: BMC Geriatrics / Issue 1/2019
Electronic ISSN: 1471-2318
DOI: https://doi.org/10.1186/s12877-019-1177-0

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