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Published in: BMC Geriatrics 1/2018

Open Access 01-12-2018 | Research article

Informal caregivers’ perspectives on health of and (potentially inappropriate) medication for (relatively) independent oldest-old people – a qualitative interview study

Authors: Nadine Janis Pohontsch, Antje Löffler, Tobias Luck, Kathrin Heser, Debora Parker, Britta Haenisch, Steffi G. Riedel-Heller, Frank Jessen, Martin Scherer

Published in: BMC Geriatrics | Issue 1/2018

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Abstract

Background

Oldest-old persons frequently receive potentially inappropriate medication. Medication use takes place under the patients’ informal caregivers’ influence. We explored informal caregivers’ perspectives on medication of (relatively) independent oldest-old persons to identify starting points for safer medication prescription/handling.

Methods

In this exploratory qualitative interview study we interviewed 45 informal caregivers of 45 oldest-old persons (23 with potentially inappropriate medication/22 without potentially inappropriate medication). Interviews were recorded, transcribed and content analyzed (deductive/inductive coding).

Results

Interviewees had little knowledge about/influence on oldest-old persons’ medication, but declared to monitor oldest-old persons’ needs for assistance. They were unaware of the concept of potentially inappropriate medication but sometimes sensitive to substance dependency. Most informal caregivers were satisfied with the oldest-old persons’ medication and viewed medication as increasing the patients’ quality of life. Inadequate communication was found between informal caregivers and general practitioners.

Conclusions

Influence of informal caregivers on (relatively) independent oldest-old persons’ medication seems low. Stakeholders need to be aware that there is a transitional period where independency of oldest-old persons decreases and support needs increase which may be missed by (in-)formal caregivers or concealed by oldest-old persons. Monitoring patients’ medication competencies; measures supporting communication between informal caregivers and health care professionals; provision of educational and support resources for informal caregivers and the acceptance of oldest-old persons’ increasing assistance needs may increase medication safety.
Literature
1.
go back to reference Lau DT, Kasper JD, Potter DEB, Lyles A, Bennett RG. Hospitalization and death associated with potentially inappropriate medication prescriptions among elderly nursing home residents. Arch Intern Med. 2005;165(1):68–74.CrossRefPubMed Lau DT, Kasper JD, Potter DEB, Lyles A, Bennett RG. Hospitalization and death associated with potentially inappropriate medication prescriptions among elderly nursing home residents. Arch Intern Med. 2005;165(1):68–74.CrossRefPubMed
2.
go back to reference Holt S, Schmiedl S, Thürmann PA. Potentially inappropriate medications in the elderly: the PRISCUS list. Dtsch Ärztebl Int. 2010;107(31–32):543–51.PubMedPubMedCentral Holt S, Schmiedl S, Thürmann PA. Potentially inappropriate medications in the elderly: the PRISCUS list. Dtsch Ärztebl Int. 2010;107(31–32):543–51.PubMedPubMedCentral
3.
go back to reference Amann U, Schmedt N, Garbe E. Prescribing of potentially inappropriate medications for the elderly: an analysis based on the PRISCUS list. Dtsch Ärztebl Int. 2012;109(5):69–75.PubMedPubMedCentral Amann U, Schmedt N, Garbe E. Prescribing of potentially inappropriate medications for the elderly: an analysis based on the PRISCUS list. Dtsch Ärztebl Int. 2012;109(5):69–75.PubMedPubMedCentral
4.
go back to reference Chang C-B, Chen J-H, Wen C-J, Kuo H-K, Lu I-S, Chiu L-S, et al. Potentially inappropriate medications in geriatric outpatients with polypharmacy: application of six sets of published explicit criteria. Br J Clin Pharmacol. 2011;72(3):482–9.CrossRefPubMedPubMedCentral Chang C-B, Chen J-H, Wen C-J, Kuo H-K, Lu I-S, Chiu L-S, et al. Potentially inappropriate medications in geriatric outpatients with polypharmacy: application of six sets of published explicit criteria. Br J Clin Pharmacol. 2011;72(3):482–9.CrossRefPubMedPubMedCentral
5.
go back to reference Dedhiya SD, Hancock E, Craig BA, Doebbeling CC, Thomas J. Incident use and outcomes associated with potentially inappropriate medication use in older adults. Am J Geriatr Pharmacother. 2010;8(6):562–70.CrossRefPubMed Dedhiya SD, Hancock E, Craig BA, Doebbeling CC, Thomas J. Incident use and outcomes associated with potentially inappropriate medication use in older adults. Am J Geriatr Pharmacother. 2010;8(6):562–70.CrossRefPubMed
6.
go back to reference Björkman IK, Fastbom J, Schmidt IK, Bernsten CB. Pharmaceutical Care of the Elderly in Europe research (PEER) group. Drug-drug interactions in the elderly. Ann Pharmacother. 2002;36(11):1675–81.CrossRefPubMed Björkman IK, Fastbom J, Schmidt IK, Bernsten CB. Pharmaceutical Care of the Elderly in Europe research (PEER) group. Drug-drug interactions in the elderly. Ann Pharmacother. 2002;36(11):1675–81.CrossRefPubMed
7.
go back to reference Page RL, Ruscin JM. The risk of adverse drug events and hospital-related morbidity and mortality among older adults with potentially inappropriate medication use. Am J Geriatr Pharmacother. 2006;4(4):297–305.CrossRefPubMed Page RL, Ruscin JM. The risk of adverse drug events and hospital-related morbidity and mortality among older adults with potentially inappropriate medication use. Am J Geriatr Pharmacother. 2006;4(4):297–305.CrossRefPubMed
8.
go back to reference Schneeweiss S, Hasford J, Göttler M, Hoffmann A, Riethling A-K, Avorn J. Admissions caused by adverse drug events to internal medicine and emergency departments in hospitals: a longitudinal population-based study. Eur J Clin Pharmacol. 2002;58(4):285–91.CrossRefPubMed Schneeweiss S, Hasford J, Göttler M, Hoffmann A, Riethling A-K, Avorn J. Admissions caused by adverse drug events to internal medicine and emergency departments in hospitals: a longitudinal population-based study. Eur J Clin Pharmacol. 2002;58(4):285–91.CrossRefPubMed
9.
go back to reference Jessen F, Kaduszkiewicz H, Daerr M, Bickel H, Pentzek M, Riedel-Heller S, et al. Anticholinergic drug use and risk for dementia: target for dementia prevention. Eur Arch Psychiatry Clin Neurosci. 2010;260(Suppl 2):S111–5.CrossRefPubMed Jessen F, Kaduszkiewicz H, Daerr M, Bickel H, Pentzek M, Riedel-Heller S, et al. Anticholinergic drug use and risk for dementia: target for dementia prevention. Eur Arch Psychiatry Clin Neurosci. 2010;260(Suppl 2):S111–5.CrossRefPubMed
10.
go back to reference Andersen R, Newman JF. Societal and individual determinants of medical care utilization in the United States. Milbank Mem Fund Q Health Soc. 1973;51(1):95–124.CrossRefPubMed Andersen R, Newman JF. Societal and individual determinants of medical care utilization in the United States. Milbank Mem Fund Q Health Soc. 1973;51(1):95–124.CrossRefPubMed
11.
go back to reference Andersen RM. Revisiting the behavioral model and access to medical care: does it matter? J Health Soc Behav. 1995;36(1):1–10.CrossRefPubMed Andersen RM. Revisiting the behavioral model and access to medical care: does it matter? J Health Soc Behav. 1995;36(1):1–10.CrossRefPubMed
12.
go back to reference Ajzen I. The theory of planned behavior. Organ Behav Hum Decis Process. 1991;50(2):179–211.CrossRef Ajzen I. The theory of planned behavior. Organ Behav Hum Decis Process. 1991;50(2):179–211.CrossRef
13.
go back to reference Rosenstock IM, Strecher VJ, Becker MH. Social learning theory and the health belief model. Health Educ Q. 1988;15(2):175–83.CrossRefPubMed Rosenstock IM, Strecher VJ, Becker MH. Social learning theory and the health belief model. Health Educ Q. 1988;15(2):175–83.CrossRefPubMed
14.
go back to reference Pohontsch NJ, Heser K, Löffler A, Haenisch B, Parker D, Luck T, et al. General practitioners’ views on (long-term) prescription and use of problematic and potentially inappropriate medication for oldest-old patients-a qualitative interview study with GPs (CIM-TRIAD study). BMC Fam Pract. 2017;18(1):22.CrossRefPubMedPubMedCentral Pohontsch NJ, Heser K, Löffler A, Haenisch B, Parker D, Luck T, et al. General practitioners’ views on (long-term) prescription and use of problematic and potentially inappropriate medication for oldest-old patients-a qualitative interview study with GPs (CIM-TRIAD study). BMC Fam Pract. 2017;18(1):22.CrossRefPubMedPubMedCentral
15.
go back to reference Anderson K, Stowasser D, Freeman C, Scott I. Prescriber barriers and enablers to minimising potentially inappropriate medications in adults: a systematic review and thematic synthesis. BMJ Open. 2014;4(12):e006544.CrossRefPubMedPubMedCentral Anderson K, Stowasser D, Freeman C, Scott I. Prescriber barriers and enablers to minimising potentially inappropriate medications in adults: a systematic review and thematic synthesis. BMJ Open. 2014;4(12):e006544.CrossRefPubMedPubMedCentral
16.
go back to reference Voigt K, Gottschall M, Köberlein-Neu J, Schübel J, Quint N, Bergmann A. Why do family doctors prescribe potentially inappropriate medication to elderly patients? BMC Fam Pract. 2016;17:93.CrossRefPubMedPubMedCentral Voigt K, Gottschall M, Köberlein-Neu J, Schübel J, Quint N, Bergmann A. Why do family doctors prescribe potentially inappropriate medication to elderly patients? BMC Fam Pract. 2016;17:93.CrossRefPubMedPubMedCentral
17.
go back to reference Heser K, Pohontsch N, Scherer M, Löffler A, Luck T, Riedel-Heller S, et al. Perspective of elderly patients on contextual factors of chronic use of potentially inappropriate medication – results of the qualitative CIM-TRIAD study. Rev. Heser K, Pohontsch N, Scherer M, Löffler A, Luck T, Riedel-Heller S, et al. Perspective of elderly patients on contextual factors of chronic use of potentially inappropriate medication – results of the qualitative CIM-TRIAD study. Rev.
18.
go back to reference Cook JM, Biyanova T, Masci C, Coyne JC. Older patient perspectives on long-term anxiolytic benzodiazepine use and discontinuation: a qualitative study. J Gen Intern Med. 2007;22(8):1094–100.CrossRefPubMedPubMedCentral Cook JM, Biyanova T, Masci C, Coyne JC. Older patient perspectives on long-term anxiolytic benzodiazepine use and discontinuation: a qualitative study. J Gen Intern Med. 2007;22(8):1094–100.CrossRefPubMedPubMedCentral
19.
go back to reference Spinewine A, Swine C, Dhillon S, Franklin BD, Tulkens PM, Wilmotte L, et al. Appropriateness of use of medicines in elderly inpatients: qualitative study. BMJ. 2005;331(7522):935.CrossRefPubMedPubMedCentral Spinewine A, Swine C, Dhillon S, Franklin BD, Tulkens PM, Wilmotte L, et al. Appropriateness of use of medicines in elderly inpatients: qualitative study. BMJ. 2005;331(7522):935.CrossRefPubMedPubMedCentral
20.
go back to reference Look KA, Stone JA. Medication management activities performed by informal caregivers of older adults. Res Soc Adm Pharm RSAP. 2018;14(5):418–26.CrossRef Look KA, Stone JA. Medication management activities performed by informal caregivers of older adults. Res Soc Adm Pharm RSAP. 2018;14(5):418–26.CrossRef
21.
go back to reference Lau DT, Berman R, Halpern L, Pickard AS, Schrauf R, Witt W. Exploring factors that influence informal caregiving in medication Management for Home Hospice Patients. J Palliat Med. 2010;13(9):1085–90.CrossRefPubMedPubMedCentral Lau DT, Berman R, Halpern L, Pickard AS, Schrauf R, Witt W. Exploring factors that influence informal caregiving in medication Management for Home Hospice Patients. J Palliat Med. 2010;13(9):1085–90.CrossRefPubMedPubMedCentral
22.
go back to reference Gillespie R, Mullan J, Harrison L. Managing medications: the role of informal caregivers of older adults and people living with dementia. A review of the literature. J Clin Nurs. 2014;23(23–24):3296–308.CrossRefPubMed Gillespie R, Mullan J, Harrison L. Managing medications: the role of informal caregivers of older adults and people living with dementia. A review of the literature. J Clin Nurs. 2014;23(23–24):3296–308.CrossRefPubMed
23.
go back to reference Maidment ID, Aston L, Moutela T, Fox CG, Hilton A. A qualitative study exploring medication management in people with dementia living in the community and the potential role of the community pharmacist. Health Expect Int J Public Particip Health Care Health Policy. 2017;20(5):929–42. Maidment ID, Aston L, Moutela T, Fox CG, Hilton A. A qualitative study exploring medication management in people with dementia living in the community and the potential role of the community pharmacist. Health Expect Int J Public Particip Health Care Health Policy. 2017;20(5):929–42.
24.
go back to reference Aston L, Hilton A, Moutela T, Shaw R, Maidment I. Exploring the evidence base for how people with dementia and their informal carers manage their medication in the community: a mixed studies review. BMC Geriatr. 2017;17(1):242.CrossRefPubMedPubMedCentral Aston L, Hilton A, Moutela T, Shaw R, Maidment I. Exploring the evidence base for how people with dementia and their informal carers manage their medication in the community: a mixed studies review. BMC Geriatr. 2017;17(1):242.CrossRefPubMedPubMedCentral
25.
go back to reference Thorpe JM, Thorpe CT, Kennelty KA, Gellad WF, Schulz R. The impact of family caregivers on potentially inappropriate medication use in noninstitutionalized older adults with dementia. Am J Geriatr Pharmacother. 2012;10(4):230–41.CrossRefPubMedPubMedCentral Thorpe JM, Thorpe CT, Kennelty KA, Gellad WF, Schulz R. The impact of family caregivers on potentially inappropriate medication use in noninstitutionalized older adults with dementia. Am J Geriatr Pharmacother. 2012;10(4):230–41.CrossRefPubMedPubMedCentral
27.
go back to reference Berlau DJ, Corrada MM, Kawas C. The prevalence of disability in the oldest-old is high and continues to increase with age: findings from the 90+ study. Int J Geriatr Psychiatry. 2009;24(11):1217–25.CrossRefPubMedPubMedCentral Berlau DJ, Corrada MM, Kawas C. The prevalence of disability in the oldest-old is high and continues to increase with age: findings from the 90+ study. Int J Geriatr Psychiatry. 2009;24(11):1217–25.CrossRefPubMedPubMedCentral
28.
29.
go back to reference Skoog I, Börjesson-Hanson A, Kern S, Johansson L, Falk H, Sigström R, et al. Decreasing prevalence of dementia in 85-year olds examined 22 years apart: the influence of education and stroke. Sci Rep. 2017;7(1):6136.CrossRefPubMedPubMedCentral Skoog I, Börjesson-Hanson A, Kern S, Johansson L, Falk H, Sigström R, et al. Decreasing prevalence of dementia in 85-year olds examined 22 years apart: the influence of education and stroke. Sci Rep. 2017;7(1):6136.CrossRefPubMedPubMedCentral
30.
go back to reference Eisele M, Zimmermann T, Köhler M, Wiese B, Heser K, Tebarth F, et al. Influence of social support on cognitive change and mortality in old age: results from the prospective multicentre cohort study AgeCoDe. BMC Geriatr. 2012;12:9.CrossRefPubMedPubMedCentral Eisele M, Zimmermann T, Köhler M, Wiese B, Heser K, Tebarth F, et al. Influence of social support on cognitive change and mortality in old age: results from the prospective multicentre cohort study AgeCoDe. BMC Geriatr. 2012;12:9.CrossRefPubMedPubMedCentral
31.
go back to reference Pohontsch N, Zimmermann T, Heinbokel C, Lehmann M, Löwe B, Scherer M. Coding of medically unexplained symptoms and somatoform disorders by general practitioners in Germany – An exploratory focus group study. BMC Fam Pract 2018;in press. Pohontsch N, Zimmermann T, Heinbokel C, Lehmann M, Löwe B, Scherer M. Coding of medically unexplained symptoms and somatoform disorders by general practitioners in Germany – An exploratory focus group study. BMC Fam Pract 2018;in press.
32.
go back to reference Pohontsch NJ, Hansen H, Schäfer I, Scherer M. General practitioners’ perception of being a doctor in urban vs. rural regions in Germany - a focus group study. Fam Pract. 2018;35(2):209–15.CrossRefPubMed Pohontsch NJ, Hansen H, Schäfer I, Scherer M. General practitioners’ perception of being a doctor in urban vs. rural regions in Germany - a focus group study. Fam Pract. 2018;35(2):209–15.CrossRefPubMed
34.
go back to reference Kvale S. Doing interviews. SAGE: London; 2008 Kvale S. Doing interviews. SAGE: London; 2008
35.
go back to reference Hsieh H-F, Shannon SE. Three approaches to qualitative content analysis. Qual Health Res. 2005;15(9):1277–88.CrossRefPubMed Hsieh H-F, Shannon SE. Three approaches to qualitative content analysis. Qual Health Res. 2005;15(9):1277–88.CrossRefPubMed
36.
go back to reference Mayring P. Qualitative Inhaltsanalyse. Grundlagen und Techniken. Beltz: Weinheim; 2010. Mayring P. Qualitative Inhaltsanalyse. Grundlagen und Techniken. Beltz: Weinheim; 2010.
37.
go back to reference Dey I. Qualitative data analysis: a user-friendly guide for social scientists. London: Rutledge; 1993.CrossRef Dey I. Qualitative data analysis: a user-friendly guide for social scientists. London: Rutledge; 1993.CrossRef
38.
go back to reference Potter J, Wetherell M. Discourse and social psychology: beyond attitudes and behaviour. London: Sage; 1987. Potter J, Wetherell M. Discourse and social psychology: beyond attitudes and behaviour. London: Sage; 1987.
39.
go back to reference Creswell JW. Research design: qualitative, quantitative, and mixed methods approaches. 00004 ed. Thousand Oaks: Sage Pubn; 2013. Creswell JW. Research design: qualitative, quantitative, and mixed methods approaches. 00004 ed. Thousand Oaks: Sage Pubn; 2013.
40.
go back to reference Caljouw MAA, Cools HJM, Gussekloo J. Natural course of care dependency in residents of long-term care facilities: prospective follow-up study. BMC Geriatr. 2014;14:67.CrossRefPubMedPubMedCentral Caljouw MAA, Cools HJM, Gussekloo J. Natural course of care dependency in residents of long-term care facilities: prospective follow-up study. BMC Geriatr. 2014;14:67.CrossRefPubMedPubMedCentral
41.
go back to reference Kingston A, Wohland P, Wittenberg R, Robinson L, Brayne C, Matthews FE, et al. Is late-life dependency increasing or not? A comparison of the cognitive function and ageing studies (CFAS). Lancet. 2017;390(10103):1676–84.CrossRefPubMedPubMedCentral Kingston A, Wohland P, Wittenberg R, Robinson L, Brayne C, Matthews FE, et al. Is late-life dependency increasing or not? A comparison of the cognitive function and ageing studies (CFAS). Lancet. 2017;390(10103):1676–84.CrossRefPubMedPubMedCentral
42.
go back to reference MacLaughlin EJ, Raehl CL, Treadway AK, Sterling TL, Zoller DP, Bond CA. Assessing medication adherence in the elderly: which tools to use in clinical practice? Drugs Aging. 2005;22(3):231–55.CrossRefPubMed MacLaughlin EJ, Raehl CL, Treadway AK, Sterling TL, Zoller DP, Bond CA. Assessing medication adherence in the elderly: which tools to use in clinical practice? Drugs Aging. 2005;22(3):231–55.CrossRefPubMed
43.
go back to reference Adelman RD, Tmanova LL, Delgado D, Dion S, Lachs MS. Caregiver burden: a clinical review. JAMA. 2014;311(10):1052–60.CrossRefPubMed Adelman RD, Tmanova LL, Delgado D, Dion S, Lachs MS. Caregiver burden: a clinical review. JAMA. 2014;311(10):1052–60.CrossRefPubMed
Metadata
Title
Informal caregivers’ perspectives on health of and (potentially inappropriate) medication for (relatively) independent oldest-old people – a qualitative interview study
Authors
Nadine Janis Pohontsch
Antje Löffler
Tobias Luck
Kathrin Heser
Debora Parker
Britta Haenisch
Steffi G. Riedel-Heller
Frank Jessen
Martin Scherer
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Geriatrics / Issue 1/2018
Electronic ISSN: 1471-2318
DOI
https://doi.org/10.1186/s12877-018-0849-5

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