Skip to main content
Top
Published in: BMC Geriatrics 1/2016

Open Access 01-12-2016 | Research article

Barricades and brickwalls – a qualitative study exploring perceptions of medication use and deprescribing in long-term care

Authors: Anna Palagyi, Lisa Keay, Jessica Harper, Jan Potter, Richard I. Lindley

Published in: BMC Geriatrics | Issue 1/2016

Login to get access

Abstract

Background

The co-administration of multiple drugs (polypharmacy) is the single most common cause of adverse drug events in the older population, and residents of long-term care facilities (LTCFs) are at particularly high risk of medication harm. ‘Deprescribing’ – the withdrawal of an inappropriate medication with goal of managing polypharmacy and improving outcomes – may improve the quality of life of LTCF residents. The RELEASE study sought to explore perceptions of medication use and the concept of deprescribing in LTCFs.

Methods

Focus groups and interviews were conducted with General Practitioners (GPs), pharmacists, nursing staff, residents and their relatives within three LTCFs in the Illawarra-Shoalhaven region of NSW, Australia. Audiotapes were transcribed verbatim and, using the Integrative Model of Behaviour Prediction as a framework, thematic analysis of transcripts was conducted using QSR NVivo 10.

Results

Participants acknowledged the burden of too many medications (time to administer, physical discomfort, cost), yet displayed passivity towards medication reduction. Residents and relatives lacked understanding of medicine indications or potential harms. Willingness to initiate and accept medication change was dependent on the GP, who emerged as a central trusted figure. GPs preferred ‘the path of least resistance’, signalling systems barriers (poor uniformity of LTCF medical records, limited trained LTCF personnel); time constraints (resident consultations, follow-up with specialists and family); and the organisation of care (collaborating with LTCF staff, pharmacists and prescribing specialists) as obstacles to deprescribing.

Conclusions

Targeted engagement is required to raise awareness of the risks of polypharmacy in LTCFs and encourage acceptance of deprescribing amongst residents and their relatives. GPs are integral to the success of deprescribing initiatives within this sector.
Appendix
Available only for authorised users
Literature
1.
go back to reference Morgan TK, Williamson M, Pirotta M, Stewart K, Myers SP, Barnes J. A national census of medicines use: a 24-h snapshot of Australians aged 50 years and older. Med J Aust. 2012;196(1):50–3.PubMedCrossRef Morgan TK, Williamson M, Pirotta M, Stewart K, Myers SP, Barnes J. A national census of medicines use: a 24-h snapshot of Australians aged 50 years and older. Med J Aust. 2012;196(1):50–3.PubMedCrossRef
2.
go back to reference Cheek J, Gilbert A, Ballantyne A, Penhall R. Factors influencing the implementation of quality use of medicines in residential aged care. Drugs Aging. 2004;21(12):813–24.PubMedCrossRef Cheek J, Gilbert A, Ballantyne A, Penhall R. Factors influencing the implementation of quality use of medicines in residential aged care. Drugs Aging. 2004;21(12):813–24.PubMedCrossRef
3.
go back to reference Stafford AC, Alswayan MS, Tenni PC. Inappropriate prescribing in older residents of Australian care homes. Journal of Clinical Pharmacy & Therapeutics. 2011;36(1):33–44.CrossRef Stafford AC, Alswayan MS, Tenni PC. Inappropriate prescribing in older residents of Australian care homes. Journal of Clinical Pharmacy & Therapeutics. 2011;36(1):33–44.CrossRef
4.
go back to reference Somers M, Rose E, Simmonds D, Whitelaw C, Calver J, Beer C. Quality use of medicines in residential aged care. Aust Fam Physician. 2010;39(6):413–6.PubMed Somers M, Rose E, Simmonds D, Whitelaw C, Calver J, Beer C. Quality use of medicines in residential aged care. Aust Fam Physician. 2010;39(6):413–6.PubMed
6.
go back to reference Johnell K, Klarin I. The relationship between number of drugs and potential drug-drug interactions in the elderly: a study of over 600,000 elderly patients from the Swedish Prescribed Drug Register. Drug Saf. 2007;30(10):911–8.PubMedCrossRef Johnell K, Klarin I. The relationship between number of drugs and potential drug-drug interactions in the elderly: a study of over 600,000 elderly patients from the Swedish Prescribed Drug Register. Drug Saf. 2007;30(10):911–8.PubMedCrossRef
7.
go back to reference Field TS, Gurwitz JH, Avorn J, McCormick D, Jain S, Eckler M, et al. Risk factors for adverse drug events among nursing home residents. Arch Intern Med. 2001;161(13):1629–34.PubMedCrossRef Field TS, Gurwitz JH, Avorn J, McCormick D, Jain S, Eckler M, et al. Risk factors for adverse drug events among nursing home residents. Arch Intern Med. 2001;161(13):1629–34.PubMedCrossRef
9.
go back to reference Runciman WB, Roughead EE, Semple SJ, Adams RJ. Adverse drug events and medication errors in Australia. Int J Qual Health Care. 2003;15 Suppl 1:i49–59.PubMedCrossRef Runciman WB, Roughead EE, Semple SJ, Adams RJ. Adverse drug events and medication errors in Australia. Int J Qual Health Care. 2003;15 Suppl 1:i49–59.PubMedCrossRef
12.
go back to reference Poudel A, Peel NM, Nissen L, Mitchell C, Gray LC, Hubbard RE. Potentially inappropriate prescribing in older patients discharged from acute care hospitals to residential aged care facilities. Ann Pharmacother. 2014;48(11):1425–33. doi:10.1177/1060028014548568.PubMedCrossRef Poudel A, Peel NM, Nissen L, Mitchell C, Gray LC, Hubbard RE. Potentially inappropriate prescribing in older patients discharged from acute care hospitals to residential aged care facilities. Ann Pharmacother. 2014;48(11):1425–33. doi:10.​1177/​1060028014548568​.PubMedCrossRef
13.
go back to reference Elliott RA, Tran T, Taylor SE, Harvey PA, Belfrage MK, Jennings RJ et al. Impact of a pharmacist-prepared interim residential care medication administration chart on gaps in continuity of medication management after discharge from hospital to residential care: a prospective pre- and post-intervention study (MedGap Study). BMJ Open. 2012;2(3). doi:10.1136/bmjopen-2012-000918. Elliott RA, Tran T, Taylor SE, Harvey PA, Belfrage MK, Jennings RJ et al. Impact of a pharmacist-prepared interim residential care medication administration chart on gaps in continuity of medication management after discharge from hospital to residential care: a prospective pre- and post-intervention study (MedGap Study). BMJ Open. 2012;2(3). doi:10.​1136/​bmjopen-2012-000918.
14.
go back to reference Reeve EG, Gnjidic D, Long J, Hilmer S. A systematic review of the emerging definition of “deprescribing” with network analysis: implications for future research and clinical practice. Br J Clin Pharmacol. 2015; doi:10.1111/bcp.12732. Reeve EG, Gnjidic D, Long J, Hilmer S. A systematic review of the emerging definition of “deprescribing” with network analysis: implications for future research and clinical practice. Br J Clin Pharmacol. 2015; doi:10.​1111/​bcp.​12732.
15.
go back to reference Scott IA, Anderson K, Freeman CR, Stowasser DA. First do no harm: a real need to deprescribe in older patients. Med J Aust. 2014;201(7):390–2.PubMedCrossRef Scott IA, Anderson K, Freeman CR, Stowasser DA. First do no harm: a real need to deprescribe in older patients. Med J Aust. 2014;201(7):390–2.PubMedCrossRef
16.
go back to reference Australian Government Department of Health and Ageing. Guidelines for a Palliative Approach in Residential Aged Care. Enhanced version. Canberra (Australia): Commonwealth of Australia, 2006. Accessed 19 May 2015. Australian Government Department of Health and Ageing. Guidelines for a Palliative Approach in Residential Aged Care. Enhanced version. Canberra (Australia): Commonwealth of Australia, 2006. Accessed 19 May 2015.
18.
go back to reference Gallagher P, Ryan C, Byrne S, Kennedy J, O'Mahony D. STOPP (Screening Tool of Older Person’s Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation. Int J Clin Pharmacol Ther. 2008;46(2):72–83.PubMedCrossRef Gallagher P, Ryan C, Byrne S, Kennedy J, O'Mahony D. STOPP (Screening Tool of Older Person’s Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation. Int J Clin Pharmacol Ther. 2008;46(2):72–83.PubMedCrossRef
19.
go back to reference Naugler CT, Brymer C, Stolee P, Arcese ZA. Development and validation of an improving prescribing in the elderly tool. Can J Clin Pharm. 2000;7(2):103–7. Naugler CT, Brymer C, Stolee P, Arcese ZA. Development and validation of an improving prescribing in the elderly tool. Can J Clin Pharm. 2000;7(2):103–7.
20.
go back to reference Gnjidic D, Le Couteur DG, Abernethy DR, Hilmer SN. A pilot randomized clinical trial utilizing the drug burden index to reduce exposure to anticholinergic and sedative medications in older people. Ann Pharmacother. 2010;44(11):1725–32. doi:10.1345/aph.1P310.PubMedCrossRef Gnjidic D, Le Couteur DG, Abernethy DR, Hilmer SN. A pilot randomized clinical trial utilizing the drug burden index to reduce exposure to anticholinergic and sedative medications in older people. Ann Pharmacother. 2010;44(11):1725–32. doi:10.​1345/​aph.​1P310.PubMedCrossRef
24.
go back to reference Reeve E, Andrews JM, Wiese MD, Hendrix I, Roberts MS, Shakib S. Feasibility of a patient-centered deprescribing process to reduce inappropriate use of proton pump inhibitors. Ann Pharmacother. 2015;49(1):29–38. doi:10.1177/1060028014558290.PubMedCrossRef Reeve E, Andrews JM, Wiese MD, Hendrix I, Roberts MS, Shakib S. Feasibility of a patient-centered deprescribing process to reduce inappropriate use of proton pump inhibitors. Ann Pharmacother. 2015;49(1):29–38. doi:10.​1177/​1060028014558290​.PubMedCrossRef
25.
go back to reference Reeve E, M.D. W, Hendrix I, Roberts MS, Shakib S. People’s Attitudes, Beliefs, and Experiences Regarding Polypharmacy and Willingness to Deprescribe. J Am Geriatr Soc. 2013;61(9):1508–14. doi:10.111/jgs.12418. Epub 2013 Aug 26. Reeve E, M.D. W, Hendrix I, Roberts MS, Shakib S. People’s Attitudes, Beliefs, and Experiences Regarding Polypharmacy and Willingness to Deprescribe. J Am Geriatr Soc. 2013;61(9):1508–14. doi:10.111/jgs.12418. Epub 2013 Aug 26.
30.
go back to reference Schuling J, Gebben H, Veehof LJG, Haaijer-Ruskamp FM. Deprescribing medication in very elderly patients with multimorbidity: the view of Dutch GPs. A qualitative study. BMC Fam Pract. 2012;13:56.PubMedPubMedCentralCrossRef Schuling J, Gebben H, Veehof LJG, Haaijer-Ruskamp FM. Deprescribing medication in very elderly patients with multimorbidity: the view of Dutch GPs. A qualitative study. BMC Fam Pract. 2012;13:56.PubMedPubMedCentralCrossRef
32.
33.
go back to reference Fishbein M, Cappella JN. The role of theory in developing effectiveness health communications. J Commun. 2006;56:S1–17.CrossRef Fishbein M, Cappella JN. The role of theory in developing effectiveness health communications. J Commun. 2006;56:S1–17.CrossRef
34.
go back to reference Yzer M. The Integrative Model of Behavioral Prediction as a Tool for Designing Health Messages. In: Cho H, editor. Health Communication Message Design. Thousand Oaks: SAGE Publications, Inc; 2012. Yzer M. The Integrative Model of Behavioral Prediction as a Tool for Designing Health Messages. In: Cho H, editor. Health Communication Message Design. Thousand Oaks: SAGE Publications, Inc; 2012.
36.
go back to reference Hilmer SN, Gnjidic D, Le Couteur DG. Thinking through the medication list: Appropriate prescribing and deprescribing in robust and frail older patients. Aust Fam Physician. 2012;41:12. Hilmer SN, Gnjidic D, Le Couteur DG. Thinking through the medication list: Appropriate prescribing and deprescribing in robust and frail older patients. Aust Fam Physician. 2012;41:12.
38.
go back to reference Australian Medical Association & Royal Australian College of General Practitioners. GP Services to Residential Aged Care: A Joint Proposal. 27 September 2006. Accessed 19 May 2015. Australian Medical Association & Royal Australian College of General Practitioners. GP Services to Residential Aged Care: A Joint Proposal. 27 September 2006. Accessed 19 May 2015.
39.
go back to reference Barter G, Cormack M. The long-term use of benzodiazepines: patients' views, accounts and experiences. Fam Pract. 1996;13(6):491–7.PubMedCrossRef Barter G, Cormack M. The long-term use of benzodiazepines: patients' views, accounts and experiences. Fam Pract. 1996;13(6):491–7.PubMedCrossRef
40.
go back to reference Roe D, Goldblatt H, Baloush-Klienman V, Swarbrick M, Davidson L. Why and how people decide to stop taking prescribed psychiatric medication: exploring the subjective process of choice. Psychiatr Rehabil J. 2009;33(1):38–46. doi:10.2975/33.1.2009.38.46.PubMedCrossRef Roe D, Goldblatt H, Baloush-Klienman V, Swarbrick M, Davidson L. Why and how people decide to stop taking prescribed psychiatric medication: exploring the subjective process of choice. Psychiatr Rehabil J. 2009;33(1):38–46. doi:10.​2975/​33.​1.​2009.​38.​46.PubMedCrossRef
42.
go back to reference Coleman EA. Falling through the cracks: challenges and opportunities for improving transitional care for persons with continuous complex care needs. J Am Geriatr Soc. 2003;51(4):549–55.PubMedCrossRef Coleman EA. Falling through the cracks: challenges and opportunities for improving transitional care for persons with continuous complex care needs. J Am Geriatr Soc. 2003;51(4):549–55.PubMedCrossRef
45.
go back to reference Morris CJ, Cantrill JA, Weiss MC. GPs’ attitudes to minor ailments. Fam Pract. 2001;18(6):581–5.PubMedCrossRef Morris CJ, Cantrill JA, Weiss MC. GPs’ attitudes to minor ailments. Fam Pract. 2001;18(6):581–5.PubMedCrossRef
46.
go back to reference Australian Institute of Health and Welfare. Residential aged care in Australia 2010–11: a statistical overview. Canberra: AIHW; 2012. Accessed 19 May 2015. Australian Institute of Health and Welfare. Residential aged care in Australia 2010–11: a statistical overview. Canberra: AIHW; 2012. Accessed 19 May 2015.
Metadata
Title
Barricades and brickwalls – a qualitative study exploring perceptions of medication use and deprescribing in long-term care
Authors
Anna Palagyi
Lisa Keay
Jessica Harper
Jan Potter
Richard I. Lindley
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Geriatrics / Issue 1/2016
Electronic ISSN: 1471-2318
DOI
https://doi.org/10.1186/s12877-016-0181-x

Other articles of this Issue 1/2016

BMC Geriatrics 1/2016 Go to the issue
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.