Skip to main content
Top
Published in: BMC Gastroenterology 1/2018

Open Access 01-12-2018 | Case report

Fitz-Hugh-Curtis syndrome associated with tuberculous salpingitis and peritonitis: a case presentation and review of literature

Authors: Laura Coremans, Frederik de Clerck

Published in: BMC Gastroenterology | Issue 1/2018

Login to get access

Abstract

Background

Fitz-Hugh-Curtis syndrome or acute perihepatitis is considered a rare complication of pelvic inflammatory disease, mostly associated with chlamydial or gonococcal salpingitis.
Peritoneal tuberculosis is a rare site of extra-pulmonary infection caused by Mycobacterium tuberculosis. Infection usually occurs after reactivation of latent tuberculous foci in the peritoneum and more seldom after contiguous spread from tuberculous salpingitis.

Case presentation

We describe a case of a 21-year old female of Somalian origin diagnosed with Fitz-Hugh Curtis syndrome associated with tuberculous salpingitis and peritonitis, presenting with new onset ascites.
Acid fast stained smear and polymerase chain reaction for Mycobacterium tuberculosis on ascitic fluid, endocervical culture and tuberculin skin test were all negative. Eventually, the diagnosis was made laparoscopically, showing multiple peritoneal white nodules and perihepatic “violin string” fibrinous strands.

Conclusions

To our knowledge, this is the first case where Fitz-Hugh-Curtis syndrome is associated with both peritoneal and genital tuberculosis and where ascites was the primary clinical finding. Female genital tuberculosis has only rarely been associated with Fitz-Hugh-Curtis syndrome and all cases presented with chronic abdominal pain and/or infertility. Ascites and peritoneal involvement was not present in any case. Moreover, most patients with Fitz-Hugh-Curtis syndrome show no evidence of generalized intra-abdominal infection and only occasionally have concomitant ascites.
Literature
1.
go back to reference Mehta JB, Dutt A, Harvill L, Mathews KM. Epidemiology of extrapulmonary tuberculosis. A comparative analysis with pre-AIDS era. Chest. 1991;99(5):1134–8.CrossRefPubMed Mehta JB, Dutt A, Harvill L, Mathews KM. Epidemiology of extrapulmonary tuberculosis. A comparative analysis with pre-AIDS era. Chest. 1991;99(5):1134–8.CrossRefPubMed
2.
go back to reference Golden MP, Vikram HR. Extrapulmonary tuberculosis: an overview. Am Fam Physician. 2005;72(9):1761–8.PubMed Golden MP, Vikram HR. Extrapulmonary tuberculosis: an overview. Am Fam Physician. 2005;72(9):1761–8.PubMed
3.
go back to reference Peter NG, Clark LR, Jaeger JR. Fitz-Hugh-Curtis syndrome: a diagnosis to consider in women with right upper quadrant pain. Cleve Clin J Med. 2004;71(3):233–9.CrossRefPubMed Peter NG, Clark LR, Jaeger JR. Fitz-Hugh-Curtis syndrome: a diagnosis to consider in women with right upper quadrant pain. Cleve Clin J Med. 2004;71(3):233–9.CrossRefPubMed
4.
go back to reference Sharma JB, Malhotra M, Arora R. Fitz-Hugh-Curtis syndrome as a result of genital tuberculosis: a report of three cases. Acta Obstet Gynecol Scand. 2003;82(3):295–7.CrossRefPubMed Sharma JB, Malhotra M, Arora R. Fitz-Hugh-Curtis syndrome as a result of genital tuberculosis: a report of three cases. Acta Obstet Gynecol Scand. 2003;82(3):295–7.CrossRefPubMed
5.
go back to reference You JS, Kim MJ, Chung HS, Chung YE, Park I, Chung SP, et al. Clinical features of Fitz-Hugh-Curtis syndrome in the emergency department. Yonsei Med J. 2012;53(4):753–8.CrossRefPubMedPubMedCentral You JS, Kim MJ, Chung HS, Chung YE, Park I, Chung SP, et al. Clinical features of Fitz-Hugh-Curtis syndrome in the emergency department. Yonsei Med J. 2012;53(4):753–8.CrossRefPubMedPubMedCentral
6.
go back to reference Tsubuku M, Hayashi S, Terahara A, Furukawa T, Ohmura G. Fitz-Hugh-Curtis syndrome: linear contrast enhancement of the surface of the liver on CT. J Comput Assist Tomogr. 2002;26(3):456–8.CrossRefPubMed Tsubuku M, Hayashi S, Terahara A, Furukawa T, Ohmura G. Fitz-Hugh-Curtis syndrome: linear contrast enhancement of the surface of the liver on CT. J Comput Assist Tomogr. 2002;26(3):456–8.CrossRefPubMed
7.
8.
go back to reference Pereira JM, Madureira AJ, Vieira A, Ramos I. Abdominal tuberculosis: imaging features. Eur J Radiol. 2005;55(2):173–80.CrossRefPubMed Pereira JM, Madureira AJ, Vieira A, Ramos I. Abdominal tuberculosis: imaging features. Eur J Radiol. 2005;55(2):173–80.CrossRefPubMed
9.
go back to reference Sanai FM, Bzeizi KI. Systematic review: tuberculous peritonitis--presenting features, diagnostic strategies and treatment. Aliment Pharmacol Ther. 2005;22(8):685–700.CrossRefPubMed Sanai FM, Bzeizi KI. Systematic review: tuberculous peritonitis--presenting features, diagnostic strategies and treatment. Aliment Pharmacol Ther. 2005;22(8):685–700.CrossRefPubMed
10.
go back to reference Runyon BA, Montano AA, Akriviadis EA, Antillon MR, Irving MA, McHutchison JG. The serum-ascites albumin gradient is superior to the exudate-transudate concept in the differential diagnosis of ascites. Ann Intern Med. 1992;117(3):215–20.CrossRefPubMed Runyon BA, Montano AA, Akriviadis EA, Antillon MR, Irving MA, McHutchison JG. The serum-ascites albumin gradient is superior to the exudate-transudate concept in the differential diagnosis of ascites. Ann Intern Med. 1992;117(3):215–20.CrossRefPubMed
11.
go back to reference Lewinsohn DM, Leonard MK, LoBue PA, Cohn DL, Daley CL, Desmond E, et al. Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention clinical practice guidelines: diagnosis of tuberculosis in adults and children. Clin Infect Dis. 2017;64(2):111–5.CrossRefPubMedPubMedCentral Lewinsohn DM, Leonard MK, LoBue PA, Cohn DL, Daley CL, Desmond E, et al. Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention clinical practice guidelines: diagnosis of tuberculosis in adults and children. Clin Infect Dis. 2017;64(2):111–5.CrossRefPubMedPubMedCentral
12.
go back to reference Ali N, Nath NC, Parvin R, Rahman A, Bhuiyan TM, Rahman M, et al. Role of ascitic fluid adenosine deaminase (ADA) and serum CA-125 in the diagnosis of tuberculous peritonitis. Bangladesh Med Res Counc Bull. 2014;40(3):89–91.CrossRefPubMed Ali N, Nath NC, Parvin R, Rahman A, Bhuiyan TM, Rahman M, et al. Role of ascitic fluid adenosine deaminase (ADA) and serum CA-125 in the diagnosis of tuberculous peritonitis. Bangladesh Med Res Counc Bull. 2014;40(3):89–91.CrossRefPubMed
13.
go back to reference Tao L, Ning HJ, Nie HM, Guo XY, Qin SY, Jiang HX. Diagnostic value of adenosine deaminase in ascites for tuberculosis ascites: a meta-analysis. Diagn Microbiol Infect Dis. 2014;79(1):102–7.CrossRefPubMed Tao L, Ning HJ, Nie HM, Guo XY, Qin SY, Jiang HX. Diagnostic value of adenosine deaminase in ascites for tuberculosis ascites: a meta-analysis. Diagn Microbiol Infect Dis. 2014;79(1):102–7.CrossRefPubMed
14.
go back to reference Simsek H, Savas MC, Kadayifci A, Tatar G. Elevated serum CA 125 concentration in patients with tuberculous peritonitis: a case-control study. Am J Gastroenterol. 1997;92(7):1174–6.PubMed Simsek H, Savas MC, Kadayifci A, Tatar G. Elevated serum CA 125 concentration in patients with tuberculous peritonitis: a case-control study. Am J Gastroenterol. 1997;92(7):1174–6.PubMed
15.
go back to reference Mas MR, Comert B, Saglamkaya U, Yamanel L, Kuzhan O, Ateskan U, et al. CA-125; a new marker for diagnosis and follow-up of patients with tuberculous peritonitis. Dig Liver Dis. 2000;32(7):595–7.CrossRefPubMed Mas MR, Comert B, Saglamkaya U, Yamanel L, Kuzhan O, Ateskan U, et al. CA-125; a new marker for diagnosis and follow-up of patients with tuberculous peritonitis. Dig Liver Dis. 2000;32(7):595–7.CrossRefPubMed
16.
go back to reference Chow KM, Chow VC, Szeto CC. Indication for peritoneal biopsy in tuberculous peritonitis. Am J Surg. 2003;185(6):567–73.CrossRefPubMed Chow KM, Chow VC, Szeto CC. Indication for peritoneal biopsy in tuberculous peritonitis. Am J Surg. 2003;185(6):567–73.CrossRefPubMed
17.
go back to reference Uzunkoy A, Harma M, Harma M. Diagnosis of abdominal tuberculosis: experience from 11 cases and review of the literature. World J Gastroenterol. 2004;10(24):3647–9.CrossRefPubMedPubMedCentral Uzunkoy A, Harma M, Harma M. Diagnosis of abdominal tuberculosis: experience from 11 cases and review of the literature. World J Gastroenterol. 2004;10(24):3647–9.CrossRefPubMedPubMedCentral
18.
go back to reference Caspi B, Wolach V, von der Walde J, Weiss Y, Appelman Z, Hagay Z. Diagnosis of abdominal tuberculosis by transabdominal ultrasound-guided needle biopsy. Ultrasound Obstet Gynecol. 2000;16(6):569–70.CrossRefPubMed Caspi B, Wolach V, von der Walde J, Weiss Y, Appelman Z, Hagay Z. Diagnosis of abdominal tuberculosis by transabdominal ultrasound-guided needle biopsy. Ultrasound Obstet Gynecol. 2000;16(6):569–70.CrossRefPubMed
19.
go back to reference Pombo F, Rodriguez E, Martin R, Lago M. CT-guided core-needle biopsy in omental pathology. Acta Radiol. 1997;38(6):978–81.CrossRefPubMed Pombo F, Rodriguez E, Martin R, Lago M. CT-guided core-needle biopsy in omental pathology. Acta Radiol. 1997;38(6):978–81.CrossRefPubMed
20.
go back to reference Wang J, Gao L, Tang S, Li T, Lei Y, Xie H, et al. A retrospective analysis on the diagnostic value of ultrasound-guided percutaneous biopsy for peritoneal lesions. World J Surg Oncol. 2013;11:251.CrossRefPubMedPubMedCentral Wang J, Gao L, Tang S, Li T, Lei Y, Xie H, et al. A retrospective analysis on the diagnostic value of ultrasound-guided percutaneous biopsy for peritoneal lesions. World J Surg Oncol. 2013;11:251.CrossRefPubMedPubMedCentral
22.
go back to reference Demir K, Okten A, Kaymakoglu S, Dincer D, Besisik F, Cevikbas U, et al. Tuberculous peritonitis--reports of 26 cases, detailing diagnostic and therapeutic problems. Eur J Gastroenterol Hepatol. 2001;13(5):581–5.CrossRefPubMed Demir K, Okten A, Kaymakoglu S, Dincer D, Besisik F, Cevikbas U, et al. Tuberculous peritonitis--reports of 26 cases, detailing diagnostic and therapeutic problems. Eur J Gastroenterol Hepatol. 2001;13(5):581–5.CrossRefPubMed
23.
go back to reference Nahid P, Dorman SE, Alipanah N, Barry PM, Brozek JL, Cattamanchi A, et al. Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America clinical practice guidelines: treatment of drug-susceptible tuberculosis. Clin Infect Dis. 2016;63(7):e147–e95.CrossRefPubMed Nahid P, Dorman SE, Alipanah N, Barry PM, Brozek JL, Cattamanchi A, et al. Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America clinical practice guidelines: treatment of drug-susceptible tuberculosis. Clin Infect Dis. 2016;63(7):e147–e95.CrossRefPubMed
24.
go back to reference Hopewell PC. Updating the international standards for tuberculosis care. Int J Tuberc Lung Dis. 2014;18(3):253.CrossRefPubMed Hopewell PC. Updating the international standards for tuberculosis care. Int J Tuberc Lung Dis. 2014;18(3):253.CrossRefPubMed
Metadata
Title
Fitz-Hugh-Curtis syndrome associated with tuberculous salpingitis and peritonitis: a case presentation and review of literature
Authors
Laura Coremans
Frederik de Clerck
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Gastroenterology / Issue 1/2018
Electronic ISSN: 1471-230X
DOI
https://doi.org/10.1186/s12876-018-0768-0

Other articles of this Issue 1/2018

BMC Gastroenterology 1/2018 Go to the issue