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BMC Anesthesiology
Published in: BMC Anesthesiology 1/2018

Open Access 01-12-2018 | Research article

Assessment of changes of regional ventilation distribution in the lung tissue depending on the driving pressure applied during high frequency jet ventilation

Authors: Szymon Bialka, Maja Copik, Katarzyna Rybczyk, Aleksander Owczarek, Ewa Jedrusik, Damian Czyzewski, Marek Filipowski, Eva Rivas, Kurt Ruetzler, Lukasz Szarpak, Hanna Misiolek

Published in: BMC Anesthesiology | Issue 1/2018

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Abstract

Background

Electrical impedance tomography (EIT) is a tool to monitor regional ventilation distribution in patient’s lungs under general anesthesia. The objective of this study was to assess the regional ventilation distribution using different driving pressures (DP) during high frequency jet ventilation (HFJV).

Methods

Prospective, observational, cross-over study. Patients undergoing rigid bronchoscopy were ventilated HFJV with DP 1.5 and 2.5 atm. Hemodynamic and ventilation parameters, as well as ventilation in different regions of the lungs in percentage of total ventilation, assessed by EIT, were recorded.

Results

Thirty-six patients scheduled for elective rigid bronchoscopy. The final analysis included thirty patients. There was no significant difference in systolic, diastolic and mean arterial blood pressure, heart rate, and peripheral saturation between the two groups. Peak inspiratory pressure, mean inspiratory pressure, tidal volume, and minute volume significantly increased in the second, compared to the first intervention group. Furthermore, there were no statistically significant differences between each time profiles in all ROI regions in EIT.

Conclusions

In our study intraoperative EIT was an effective method of functional monitoring of the lungs during HFJV for rigid bronchoscopy procedure. Lower driving pressure was as effective in providing sufficient ventilation distribution through the lungs as the higher driving pressure but characterized by lower airway pressure.

Trial registration

The study was registered on ClinicalTrials.gov under no. NCT02997072.
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Metadata
Title
Assessment of changes of regional ventilation distribution in the lung tissue depending on the driving pressure applied during high frequency jet ventilation
Authors
Szymon Bialka
Maja Copik
Katarzyna Rybczyk
Aleksander Owczarek
Ewa Jedrusik
Damian Czyzewski
Marek Filipowski
Eva Rivas
Kurt Ruetzler
Lukasz Szarpak
Hanna Misiolek
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Anesthesiology / Issue 1/2018
Electronic ISSN: 1471-2253
DOI
https://doi.org/10.1186/s12871-018-0552-2

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