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Published in: BMC Anesthesiology 1/2018

Open Access 01-12-2018 | Research article

Comparative study of ultrasound-guided paravertebral block versus intravenous tramadol for postoperative pain control in percutaneous nephrolithotomy

Authors: Zehra Hatipoglu, Ersel Gulec, Mediha Turktan, Volkan Izol, Atilla Arıdogan, Yasemin Gunes, Dilek Ozcengiz

Published in: BMC Anesthesiology | Issue 1/2018

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Abstract

Background

Percutaneous nephrolithotomy (PCNL) is a minimally invasive surgical procedure for renal calculi, and nephrostomy tubes lead to postoperative pain after PCNL. Regional techniques (e.g., epidural analgesia and peripheral blocks) and opioids are applied for postoperative pain treatment. The aim of this study was to compare effectiveness of ultrasound-guided paravertebral block (PVB) and tramadol on postoperative pain in patients who underwent PCNL.

Method

Fifty-three patients were included in this prospective randomized study. The patients were allocated into two groups: the PVB group (group P, n = 26) and the tramadol group (group T, n = 27). All patients were administered standard general anaesthesia. Ultrasound-guided PVB was performed at the T11- L1 levels using 0.5% bupivacaine for a total dose of 15 mL in group P. Patients in group T were intravenously administered a loading dose of 1 mg/kg tramadol. Patients in both groups were given patient-controlled analgesia. Haemodynamic parameters, visual analogue scale (VAS) scores, side effects, and complications, tramadol consumption and additional analgesic requirements of the patients were recorded after surgery.

Results

Haemodynamic parameters were statistically similar between the groups. The VAS in group P were statistically lower than in group T. In the 24-h period after surgery, total PCA tramadol consumption was statistically lower in group P than in group T. The use of supplemental analgesic in group T was higher than in group P.

Conclusions

Ultrasound-guided PVB was found to be an effective analgesia compared to tramadol, and no additional complications were encountered.

Trial registration

ClinicalTrials.gov, NCT02412930, date of registration: March 27, 2015, retrospectively registered.
Literature
1.
go back to reference Yuan H, Zheng S, Liu L, Han P, Wang J, Wei Q. The efficacy and safety of tubeless percutaneous nephrolithotomy: a systematic review and meta-analysis. Urol Res. 2011;39:401–10.CrossRefPubMed Yuan H, Zheng S, Liu L, Han P, Wang J, Wei Q. The efficacy and safety of tubeless percutaneous nephrolithotomy: a systematic review and meta-analysis. Urol Res. 2011;39:401–10.CrossRefPubMed
2.
go back to reference Aydoğan H, Kucuk A, Yuce HH, Karahan MA, Ciftci H, Gulum M, et al. Adding 75 mg pregabalin to analgesic regimen reduces pain scores and opioid consumption in adults following percutaneous nephrolithotomy. Rev Bras Anestesiol. 2014;64:335–42.CrossRefPubMed Aydoğan H, Kucuk A, Yuce HH, Karahan MA, Ciftci H, Gulum M, et al. Adding 75 mg pregabalin to analgesic regimen reduces pain scores and opioid consumption in adults following percutaneous nephrolithotomy. Rev Bras Anestesiol. 2014;64:335–42.CrossRefPubMed
3.
go back to reference Parikh GP, Shah VR, Vora KS, Parikh BK, Modi MP, Panchal ARUN. Ultrasound guided peritubal infiltration of 0.25% ropivacaine for postoperative pain relief in percutaneous nephrolithotomy. Middle East J Anaesthesiol. 2013;22:149–54.PubMed Parikh GP, Shah VR, Vora KS, Parikh BK, Modi MP, Panchal ARUN. Ultrasound guided peritubal infiltration of 0.25% ropivacaine for postoperative pain relief in percutaneous nephrolithotomy. Middle East J Anaesthesiol. 2013;22:149–54.PubMed
4.
go back to reference Ozkan D, Akkaya T, Karakoyunlu N, Arık E, Ergil J, Koc Z, et al. Effect of ultrasound-guided intercostal nerve block on postoperative pain after percutaneous nephrolithotomy: prospective randomized controlled study. Anaesthesist. 2013;62:988–94.CrossRefPubMed Ozkan D, Akkaya T, Karakoyunlu N, Arık E, Ergil J, Koc Z, et al. Effect of ultrasound-guided intercostal nerve block on postoperative pain after percutaneous nephrolithotomy: prospective randomized controlled study. Anaesthesist. 2013;62:988–94.CrossRefPubMed
5.
go back to reference Borle AP, Chhabra A, Subramaniam R, Rewari V, Sinha R, Ramachandran R, et al. Analgesic efficacy of paravertebral bupivacaine during percutaneous nephrolithotomy: an observer blinded, randomized controlled trial. J Endourol. 2014;28:1085–90.CrossRefPubMed Borle AP, Chhabra A, Subramaniam R, Rewari V, Sinha R, Ramachandran R, et al. Analgesic efficacy of paravertebral bupivacaine during percutaneous nephrolithotomy: an observer blinded, randomized controlled trial. J Endourol. 2014;28:1085–90.CrossRefPubMed
6.
go back to reference Ak K, Gursoy S, Duger C, Isbir AC, Kaygusuz K, Ozdemir Kol I, et al. Thoracic paravertebral block for postoperative pain management in percutaneous nephrolithotomy patients: a randomized controlled clinical trial. Med Princ Pract. 2013;22:229–33.CrossRefPubMed Ak K, Gursoy S, Duger C, Isbir AC, Kaygusuz K, Ozdemir Kol I, et al. Thoracic paravertebral block for postoperative pain management in percutaneous nephrolithotomy patients: a randomized controlled clinical trial. Med Princ Pract. 2013;22:229–33.CrossRefPubMed
7.
go back to reference Splinter WM, Thomson ME. Somatic paravertebral block decreases opioid requirements in children undergoing appendectomy. Can J Anesth. 2010;57:206–10.CrossRefPubMed Splinter WM, Thomson ME. Somatic paravertebral block decreases opioid requirements in children undergoing appendectomy. Can J Anesth. 2010;57:206–10.CrossRefPubMed
8.
go back to reference Yeung JH, Gates S, Naidu BV, Wilson MJ, Gao SF. Paravertebral block versus thoracic epidural for patients undergoing thoracotomy. Cochrane Database Syst Rev. 2016;2:CD009121.PubMed Yeung JH, Gates S, Naidu BV, Wilson MJ, Gao SF. Paravertebral block versus thoracic epidural for patients undergoing thoracotomy. Cochrane Database Syst Rev. 2016;2:CD009121.PubMed
9.
go back to reference Lewis SR, Price A, Walker KJ, McGrattan K, Smith AF. Ultrasound guidance for upper and lower limb blocks. Cochrane Database Syst Rev. 2015;11:CD006459. Lewis SR, Price A, Walker KJ, McGrattan K, Smith AF. Ultrasound guidance for upper and lower limb blocks. Cochrane Database Syst Rev. 2015;11:CD006459.
10.
go back to reference Radbruch L, Grond S, Lehmann KA. A risk-benefit assessment of tramadol in the management of pain. Drug Saf. 1996;15:8–29.CrossRefPubMed Radbruch L, Grond S, Lehmann KA. A risk-benefit assessment of tramadol in the management of pain. Drug Saf. 1996;15:8–29.CrossRefPubMed
11.
go back to reference Kaya FN, Turker G, Mogol EB, Bayraktar S. Thoracic paravertebral block for video-assisted thoracoscopic surgery: single injection versus multiple injections. J Cardiothorac Vasc Anesth. 2012;26:90–4.CrossRefPubMed Kaya FN, Turker G, Mogol EB, Bayraktar S. Thoracic paravertebral block for video-assisted thoracoscopic surgery: single injection versus multiple injections. J Cardiothorac Vasc Anesth. 2012;26:90–4.CrossRefPubMed
12.
go back to reference Rashwan MD, Elbealy ME. A comparison of the effects of epidural anesthesia, lumbar paravertebral block and general anesthesia in percutaneous nephrolithotomy. J Med Sci. 2008;8:170–6.CrossRef Rashwan MD, Elbealy ME. A comparison of the effects of epidural anesthesia, lumbar paravertebral block and general anesthesia in percutaneous nephrolithotomy. J Med Sci. 2008;8:170–6.CrossRef
13.
go back to reference Terkawi AS, Tsang S, Sessler DI, Terkawi RS, Nunemaker MS, Durieux ME, et al. Improving analgesic efficacy and safety of thoracic paravertebral block for breast surgery: a mixed-effects meta-analysis. Pain Physician. 2015;18:757–80. Terkawi AS, Tsang S, Sessler DI, Terkawi RS, Nunemaker MS, Durieux ME, et al. Improving analgesic efficacy and safety of thoracic paravertebral block for breast surgery: a mixed-effects meta-analysis. Pain Physician. 2015;18:757–80.
14.
go back to reference Hutchins J, Apostolidou I, Shumway S, Kelly R, Wang Q, Foster C, et al. Paravertebral catheter use for postoperative pain control in patients after lung transplant surgery: a prospective observational study. J Cardiothorac Vasc Anesth. 2017;31(1):142–6.CrossRefPubMed Hutchins J, Apostolidou I, Shumway S, Kelly R, Wang Q, Foster C, et al. Paravertebral catheter use for postoperative pain control in patients after lung transplant surgery: a prospective observational study. J Cardiothorac Vasc Anesth. 2017;31(1):142–6.CrossRefPubMed
15.
go back to reference Baik JS, Oh AY, Cho CW, Shin HJ, Han SH, Ryu JH. Thoracic paravertebral block for nephrectomy: a randomized, controlled, observer-blinded study. Pain Med. 2014;15:850–6.CrossRefPubMed Baik JS, Oh AY, Cho CW, Shin HJ, Han SH, Ryu JH. Thoracic paravertebral block for nephrectomy: a randomized, controlled, observer-blinded study. Pain Med. 2014;15:850–6.CrossRefPubMed
16.
go back to reference Buckenmaier CC III, Kwon KH, Howard RS, McKnight GM, Shriver CD, Fritz WT, et al. Double-blinded, placebo-controlled, prospective randomized trial evaluating the efficacy of paravertebral block with and without continuous paravertebral block analgesia in outpatient breast cancer surgery. Pain Med. 2010;11:790–9.CrossRefPubMed Buckenmaier CC III, Kwon KH, Howard RS, McKnight GM, Shriver CD, Fritz WT, et al. Double-blinded, placebo-controlled, prospective randomized trial evaluating the efficacy of paravertebral block with and without continuous paravertebral block analgesia in outpatient breast cancer surgery. Pain Med. 2010;11:790–9.CrossRefPubMed
17.
go back to reference Baidya DK, Khanna P, Maitra S. Analgesic efficacy and safety of thoracic paravertebral and epidural analgesia for thoracic surgery: a systematic review and meta-analysis. Interact Cardiovasc Thorac Surg. 2014;18:626–35.CrossRefPubMed Baidya DK, Khanna P, Maitra S. Analgesic efficacy and safety of thoracic paravertebral and epidural analgesia for thoracic surgery: a systematic review and meta-analysis. Interact Cardiovasc Thorac Surg. 2014;18:626–35.CrossRefPubMed
18.
go back to reference Cheng GS, Ilfeld BM. A review of postoperative analgesia for breast cancer surgery. Pain. 2016;6:603–18. Cheng GS, Ilfeld BM. A review of postoperative analgesia for breast cancer surgery. Pain. 2016;6:603–18.
19.
go back to reference Coopey SB, Specht MC, Warren L, Smith BL, Winograd JM, Fleischmann K. Use of preoperative paravertebral block decreases length of stay in patients undergoing mastectomy plus immediate reconstruction. Ann Surg Oncol. 2013;20(4):1282–6.CrossRefPubMed Coopey SB, Specht MC, Warren L, Smith BL, Winograd JM, Fleischmann K. Use of preoperative paravertebral block decreases length of stay in patients undergoing mastectomy plus immediate reconstruction. Ann Surg Oncol. 2013;20(4):1282–6.CrossRefPubMed
20.
go back to reference Naja ZM, El-Rajab M, Al-Tannir MA, Ziade FM, Tayara K, Younes F, et al. Thoracic paravertebral block: influence of the number of injections. Anesth Pain Med. 2006;31:196–201. Naja ZM, El-Rajab M, Al-Tannir MA, Ziade FM, Tayara K, Younes F, et al. Thoracic paravertebral block: influence of the number of injections. Anesth Pain Med. 2006;31:196–201.
21.
go back to reference Naja Z, Lönnqvist PA. Somatic paravertebral nerve blockade. Incidence of failed block and complications. Anaesthesia. 2001;56:1184–8.CrossRefPubMed Naja Z, Lönnqvist PA. Somatic paravertebral nerve blockade. Incidence of failed block and complications. Anaesthesia. 2001;56:1184–8.CrossRefPubMed
22.
go back to reference Albi-Feldzer A, Duceau B, Nguessom W, Jayr C. A severe complication after ultrasound-guided thoracic paravertebral block for breast cancer surgery: total spinal anaesthesia: a case report. Eur J Anaesthesiol. 2016;33:949–51.CrossRefPubMed Albi-Feldzer A, Duceau B, Nguessom W, Jayr C. A severe complication after ultrasound-guided thoracic paravertebral block for breast cancer surgery: total spinal anaesthesia: a case report. Eur J Anaesthesiol. 2016;33:949–51.CrossRefPubMed
24.
go back to reference Schnabel A, Reichl SU, Kranke P, Pogatzki-Zahn EM, Zahn PK. Efficacy and safety of paravertebral blocks in breast surgery: a meta-analysis of randomized controlled trials. Br J Anaesth. 2010;105:842–52.CrossRefPubMed Schnabel A, Reichl SU, Kranke P, Pogatzki-Zahn EM, Zahn PK. Efficacy and safety of paravertebral blocks in breast surgery: a meta-analysis of randomized controlled trials. Br J Anaesth. 2010;105:842–52.CrossRefPubMed
25.
go back to reference Berde CB, Strichartz GR. Local anesthetics. In: Miller RD, editor. Miller’s anesthesia. 8th ed. Philadelphia: Elsevier; 2014. Berde CB, Strichartz GR. Local anesthetics. In: Miller RD, editor. Miller’s anesthesia. 8th ed. Philadelphia: Elsevier; 2014.
26.
go back to reference Abdallah FW, Morgan PJ, Cil T, McNaught A, Escallon JM, Semple JL, et al. Ultrasound-guided multilevel paravertebral blocks and total intravenous anesthesia improve the quality of recovery after ambulatory breast tumor resection. Anesthesiology. 2014;120:703–13.CrossRefPubMed Abdallah FW, Morgan PJ, Cil T, McNaught A, Escallon JM, Semple JL, et al. Ultrasound-guided multilevel paravertebral blocks and total intravenous anesthesia improve the quality of recovery after ambulatory breast tumor resection. Anesthesiology. 2014;120:703–13.CrossRefPubMed
Metadata
Title
Comparative study of ultrasound-guided paravertebral block versus intravenous tramadol for postoperative pain control in percutaneous nephrolithotomy
Authors
Zehra Hatipoglu
Ersel Gulec
Mediha Turktan
Volkan Izol
Atilla Arıdogan
Yasemin Gunes
Dilek Ozcengiz
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Anesthesiology / Issue 1/2018
Electronic ISSN: 1471-2253
DOI
https://doi.org/10.1186/s12871-018-0479-7

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