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Published in: BMC Anesthesiology 1/2015

Open Access 01-12-2015 | Research article

Clinical practice guidelines for the management of neuropathic pain: a systematic review

Authors: Yunkun Deng, Lei Luo, Yuhuai Hu, Kaiyun Fang, Jin Liu

Published in: BMC Anesthesiology | Issue 1/2015

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Abstract

Background

The management of neuropathic pain (NP) is challenging despite it being the recent focus of extensive research. A number of clinical practice guidelines (CPGs) for the management of NP have been published worldwide over the past 2 decades. This study aimed to assess the quality of these CPGs.

Methods

We performed a systematic review of published CPGs for the management of NP. Three reviewers independently assessed the quality of the CPGs using the Appraisal of Guidelines Research and Evaluation II (AGREE-II) instrument, and recommendations of CPGs were also appraised.

Results

A total of 16 CPGs were included. Thirteen CPGs were developed using an evidence-based approach, and the remaining CPGs were produced by consensus panels. None of CPGs obtained a score greater than 50 % in all six AGREE II instrument domains mainly owing to poor performance in the “Applicability” domain. The highest score of the CPGs was achieved in “Clarity and Presentation” domain, followed by “Scope and Purpose” and “Editorial Independence” domains, and the lowest scores were found the in “Applicability” domain. The majority of the CPG recommendations on the management of patients with NP were relatively consistent, especially regarding the recommendation of stepwise treatment with medication.

Conclusions

Greater efforts are needed not only to improve the quality of development and presentation of the CPGs, but also to provide more efficacy evidence for the management of patients with NP.
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Metadata
Title
Clinical practice guidelines for the management of neuropathic pain: a systematic review
Authors
Yunkun Deng
Lei Luo
Yuhuai Hu
Kaiyun Fang
Jin Liu
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Anesthesiology / Issue 1/2015
Electronic ISSN: 1471-2253
DOI
https://doi.org/10.1186/s12871-015-0150-5

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