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Published in: Archives of Dermatological Research 3/2014

01-04-2014 | Original Paper

Clinical practice guidelines for treatment of acne vulgaris: a critical appraisal using the AGREE II instrument

Authors: Gloria Sanclemente, Jorge-Luis Acosta, Maria-Eulalia Tamayo, Xavier Bonfill, Pablo Alonso-Coello

Published in: Archives of Dermatological Research | Issue 3/2014

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Abstract

A significant number of clinical practice guidelines (CPGs) about the treatment of acne vulgaris in adolescents and adults have been published worldwide. However, little is known about the quality of CPGs in this field. The aim of this study was to appraise the methodological quality of published acne vulgaris CPGs. We performed a systematic review of published CPGs on acne vulgaris therapy from July 2002 to July 2012. Three reviewers independently assessed each CPG using the AGREE II instrument. A standardized score was calculated for each of the six domains. Our search strategy identified 103 citations but just six met our inclusion criteria. Agreement among reviewers was very good: 0.981. The domains that scored better were: “scope and purpose” and “clarity and presentation”. Those that scored worse were “stakeholder involvement”, “rigor of development”, and “applicability”. The European and the Malaysian CPGs were the only recommended with no further modifications. In addition, the Mexican, Colombian and the United States guidelines were recommended with provisos, with lower scores regarding stakeholder involvement, rigor of development and applicability. Only two guidelines clearly reported outcome measures for evaluating efficacy or included quality of life outcomes. CPGs varied regarding the consideration of light/laser therapy or consideration of complementary/alternative medicines. None of them included cost considerations of drugs such as systemic isotretinoin. In conclusion, published acne vulgaris CPGs for acne therapy vary in quality with a clear need to improve their methodological rigor. This could be achieved with the adherence to current CPGs development standards.
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Metadata
Title
Clinical practice guidelines for treatment of acne vulgaris: a critical appraisal using the AGREE II instrument
Authors
Gloria Sanclemente
Jorge-Luis Acosta
Maria-Eulalia Tamayo
Xavier Bonfill
Pablo Alonso-Coello
Publication date
01-04-2014
Publisher
Springer Berlin Heidelberg
Published in
Archives of Dermatological Research / Issue 3/2014
Print ISSN: 0340-3696
Electronic ISSN: 1432-069X
DOI
https://doi.org/10.1007/s00403-013-1394-x

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