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Published in: Environmental Health and Preventive Medicine 1/2017

Open Access 01-12-2017 | Research article

Evaluating prevalence and risk factors of building-related symptoms among office workers: Seasonal characteristics of symptoms and psychosocial and physical environmental factors

Authors: Kenichi Azuma, Koichi Ikeda, Naoki Kagi, U Yanagi, Haruki Osawa

Published in: Environmental Health and Preventive Medicine | Issue 1/2017

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Abstract

Background

Psychosocial and environmental factors at the workplace play a significant role in building-related symptoms (BRSs). Environmental factors change during summer cooling and winter heating using air-conditioning systems. Thus, significant risk factors in each season need to be clarified.

Methods

A nationwide cross-sectional study was conducted during summer in Japan and seasonal differences between summer and winter were evaluated. Self-administered questionnaires were distributed to 489 offices. Possible risk factors for BRSs associated with the work environment, indoor air quality, and job stressors were examined by multiple regression analyses.

Results

Among people having at least one BRS, the prevalence of BRSs in summer (27.8%) was slightly higher than that in winter (24.9%). High prevalence was observed for eye and nasal symptoms related to dryness and general symptoms related to psychological distress in both seasons. Analyses revealed that dryness of air was an important and significant risk factor associated with BRSs, and job stressors were significantly associated with general symptoms in both seasons. Conversely, humidity was a significant risk factor of general symptoms in summer (odds ratio, 1.20; 95% confidence interval, 1.02–1.43). Carpeting, recently painted walls, and unpleasant chemical odors in summer and noise, dust and dirt, and unpleasant odors such as body or food odors in both seasons were significant risk factors for BRSs.

Conclusions

Improvements in the physical environmental qualities in an office throughout the year are important along with the reduction in psychological distress related to work.
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Literature
4.
go back to reference Norbäck D, Torgén M, Edling C. Volatile organic compounds, respirable dust, and personal factors related to prevalence and incidence of sick building syndrome in primary schools. Br J Ind Med. 1990;47:733–41.PubMedPubMedCentral Norbäck D, Torgén M, Edling C. Volatile organic compounds, respirable dust, and personal factors related to prevalence and incidence of sick building syndrome in primary schools. Br J Ind Med. 1990;47:733–41.PubMedPubMedCentral
5.
go back to reference Runeson R, Wahlstedt K, Wieslander G, Norbäck D. Personal and psychosocial factors and symptoms compatible with sick building syndrome in the Swedish workforce. Indoor Air. 2006;16:445–53.CrossRefPubMed Runeson R, Wahlstedt K, Wieslander G, Norbäck D. Personal and psychosocial factors and symptoms compatible with sick building syndrome in the Swedish workforce. Indoor Air. 2006;16:445–53.CrossRefPubMed
6.
go back to reference Runeson R, Norbäck D, Klinteberg B, Edling C. The influence of personality, measured by the Karolinska Scales of Personality (KSP), on symptoms among subjects in suspected sick buildings. Indoor Air. 2004;14:394–404.CrossRefPubMed Runeson R, Norbäck D, Klinteberg B, Edling C. The influence of personality, measured by the Karolinska Scales of Personality (KSP), on symptoms among subjects in suspected sick buildings. Indoor Air. 2004;14:394–404.CrossRefPubMed
7.
go back to reference Fisk WJ, Mirer AG, Mendell MJ. Quantitative relationship of sick building syndrome symptoms with ventilation rates. Indoor Air. 2009;19:159–65.CrossRefPubMed Fisk WJ, Mirer AG, Mendell MJ. Quantitative relationship of sick building syndrome symptoms with ventilation rates. Indoor Air. 2009;19:159–65.CrossRefPubMed
8.
go back to reference Mendell MJ, Lei-Gomez Q, Mirer AG, Seppänen O, Brunner G. Risk factors in heating, ventilating, and air-conditioning systems for occupant symptoms in US office buildings: the US EPA BASE study. Indoor Air. 2008;8:301–16.CrossRef Mendell MJ, Lei-Gomez Q, Mirer AG, Seppänen O, Brunner G. Risk factors in heating, ventilating, and air-conditioning systems for occupant symptoms in US office buildings: the US EPA BASE study. Indoor Air. 2008;8:301–16.CrossRef
9.
go back to reference Apter A, Bracker A, Hodgson M, Sidman J, Leung WY. Epidemiology of the sick building syndrome. J Allergy Clin Immunol. 1994;94:277–88.CrossRefPubMed Apter A, Bracker A, Hodgson M, Sidman J, Leung WY. Epidemiology of the sick building syndrome. J Allergy Clin Immunol. 1994;94:277–88.CrossRefPubMed
10.
go back to reference Bluyssen PM, Roda C, Mandin C, Fossati S, Carrer P, de Kluizenaar Y, et al. Self-reported health and comfort in ‘modern’ office buildings: first results from the European OFFICAIR study. Indoor Air. 2016;26:298–317.CrossRefPubMed Bluyssen PM, Roda C, Mandin C, Fossati S, Carrer P, de Kluizenaar Y, et al. Self-reported health and comfort in ‘modern’ office buildings: first results from the European OFFICAIR study. Indoor Air. 2016;26:298–317.CrossRefPubMed
11.
go back to reference Fisk WJ, Lei-Gomez Q, Mendell MJ. Meta-analyses of the associations of respiratory health effects with dampness and mold in homes. Indoor Air. 2007;17:284–96.CrossRefPubMed Fisk WJ, Lei-Gomez Q, Mendell MJ. Meta-analyses of the associations of respiratory health effects with dampness and mold in homes. Indoor Air. 2007;17:284–96.CrossRefPubMed
12.
go back to reference Maddalena R, Mendell MJ, Eliseeva K, Chan WR, Sullivan DP, Russell M, et al. Effects of ventilation rate per person and per floor area on perceived air quality, sick building syndrome symptoms, and decision-making. Indoor Air. 2015;25:362–70.CrossRefPubMed Maddalena R, Mendell MJ, Eliseeva K, Chan WR, Sullivan DP, Russell M, et al. Effects of ventilation rate per person and per floor area on perceived air quality, sick building syndrome symptoms, and decision-making. Indoor Air. 2015;25:362–70.CrossRefPubMed
13.
go back to reference Magnavita N. Work-related symptoms in indoor environments: a puzzling problem for the occupational physician. Int Arch Occup Environ Health. 2015;88:185–96.CrossRefPubMed Magnavita N. Work-related symptoms in indoor environments: a puzzling problem for the occupational physician. Int Arch Occup Environ Health. 2015;88:185–96.CrossRefPubMed
14.
go back to reference Marmot AF, Stafford JM, Stansfeld SA, Warwick E, Marmot MG. Building health: an epidemiological study of “sick building syndrome” in the Whitehall II study. Occup Environ Med. 2006;63:283–9.CrossRefPubMedPubMedCentral Marmot AF, Stafford JM, Stansfeld SA, Warwick E, Marmot MG. Building health: an epidemiological study of “sick building syndrome” in the Whitehall II study. Occup Environ Med. 2006;63:283–9.CrossRefPubMedPubMedCentral
15.
go back to reference Norbäck D, Nordström K. Sick building syndrome in relation to air exchange rate, CO(2), room temperature and relative air humidity in university computer classrooms: an experimental study. Int Arch Occup Environ Health. 2008;82:21–30.CrossRefPubMed Norbäck D, Nordström K. Sick building syndrome in relation to air exchange rate, CO(2), room temperature and relative air humidity in university computer classrooms: an experimental study. Int Arch Occup Environ Health. 2008;82:21–30.CrossRefPubMed
16.
go back to reference Niven R, Fletcher A, Pickering C, Faragher E, Potter I, Booth W, et al. Building sickness syndrome in healthy and unhealthy buildings: an epidemiological and environmental assessment with cluster analysis. Occup Environ Med. 2000;57:627–34.CrossRefPubMedPubMedCentral Niven R, Fletcher A, Pickering C, Faragher E, Potter I, Booth W, et al. Building sickness syndrome in healthy and unhealthy buildings: an epidemiological and environmental assessment with cluster analysis. Occup Environ Med. 2000;57:627–34.CrossRefPubMedPubMedCentral
17.
go back to reference Ruotsalainen R, Jaakkola N, Jaakkola JJ. Dampness and molds in day-care centers as an occupational health problem. Int Arch Occup Environ Health. 1995;66:369–74.CrossRefPubMed Ruotsalainen R, Jaakkola N, Jaakkola JJ. Dampness and molds in day-care centers as an occupational health problem. Int Arch Occup Environ Health. 1995;66:369–74.CrossRefPubMed
18.
go back to reference Teeuw KB, Vandenbroucke-Grauls CM, Verhoef J. Airborne gram-negative bacteria and endotoxin in sick building syndrome. A study in Dutch governmental office buildings. Arch Intern Med. 1994;154:2339–45.CrossRefPubMed Teeuw KB, Vandenbroucke-Grauls CM, Verhoef J. Airborne gram-negative bacteria and endotoxin in sick building syndrome. A study in Dutch governmental office buildings. Arch Intern Med. 1994;154:2339–45.CrossRefPubMed
19.
go back to reference Zhang X, Sahlberg B, Wieslander G, Janson C, Gislason T, Norbäck D. Dampness and moulds in workplace buildings: associations with incidence and remission of sick building syndrome (SBS) and biomarkers of inflammation in a 10 year follow-up study. Sci Total Environ. 2012;430:75–81.CrossRefPubMed Zhang X, Sahlberg B, Wieslander G, Janson C, Gislason T, Norbäck D. Dampness and moulds in workplace buildings: associations with incidence and remission of sick building syndrome (SBS) and biomarkers of inflammation in a 10 year follow-up study. Sci Total Environ. 2012;430:75–81.CrossRefPubMed
20.
go back to reference Chao HJ, Schwartz J, Milton DK, Burge HA. The work environment and workers’ health in four large office buildings. Environ Health Perspect. 2003;111:1242–8.CrossRefPubMedPubMedCentral Chao HJ, Schwartz J, Milton DK, Burge HA. The work environment and workers’ health in four large office buildings. Environ Health Perspect. 2003;111:1242–8.CrossRefPubMedPubMedCentral
21.
go back to reference Hansen AM, Meyer HW, Gyntelberg F. Building-related symptoms and stress indicators. Indoor Air. 2008;18:440–6.CrossRefPubMed Hansen AM, Meyer HW, Gyntelberg F. Building-related symptoms and stress indicators. Indoor Air. 2008;18:440–6.CrossRefPubMed
22.
go back to reference Kinman G, Griffin M. Psychosocial factors and gender as predictors of symptoms associated with sick building syndrome. Stress Health. 2008;24:165–71.CrossRef Kinman G, Griffin M. Psychosocial factors and gender as predictors of symptoms associated with sick building syndrome. Stress Health. 2008;24:165–71.CrossRef
23.
go back to reference Runeson R, Norbäck D. Sick building syndrome (SBS) and sick house syndrome (SHS) in relation to psychosocial stress at work in the Swedish workforce. Int Arch Occup Environ Health. 2013;86:915–22.CrossRef Runeson R, Norbäck D. Sick building syndrome (SBS) and sick house syndrome (SHS) in relation to psychosocial stress at work in the Swedish workforce. Int Arch Occup Environ Health. 2013;86:915–22.CrossRef
24.
go back to reference Azuma K, Ikeda K, Osawa H, Kagi N, Yanagi U, Saito H, et al. Actual status of environmental sanitation and building maintenance in Japan. Trans Soc Heating Air-Conditioning Sanitary Eng Japan. 2012;179:19–26 (in Japanese with English abstract). Azuma K, Ikeda K, Osawa H, Kagi N, Yanagi U, Saito H, et al. Actual status of environmental sanitation and building maintenance in Japan. Trans Soc Heating Air-Conditioning Sanitary Eng Japan. 2012;179:19–26 (in Japanese with English abstract).
25.
26.
go back to reference Wolkoff P. Ocular discomfort by environmental and personal risk factors altering the precorneal tear film. Toxicol Lett. 2010;199:203–12.CrossRefPubMed Wolkoff P. Ocular discomfort by environmental and personal risk factors altering the precorneal tear film. Toxicol Lett. 2010;199:203–12.CrossRefPubMed
27.
go back to reference Khatri M, Bello D, Gaines P, Martin J, Pal AK, Gore R, et al. Nanoparticles from photocopiers induce oxidative stress and upper respiratory tract inflammation in healthy volunteers. Nanotoxicology. 2013;7:1014–27.CrossRefPubMed Khatri M, Bello D, Gaines P, Martin J, Pal AK, Gore R, et al. Nanoparticles from photocopiers induce oxidative stress and upper respiratory tract inflammation in healthy volunteers. Nanotoxicology. 2013;7:1014–27.CrossRefPubMed
28.
go back to reference Azuma K, Ikeda K, Kagi N, Yanagi U, Osawa H. Prevalence and risk factors associated with nonspecific building-related symptoms in office employees in Japan: relationships between work environment, Indoor Air Quality, and occupational stress. Indoor Air. 2015;25:499–511.CrossRefPubMed Azuma K, Ikeda K, Kagi N, Yanagi U, Osawa H. Prevalence and risk factors associated with nonspecific building-related symptoms in office employees in Japan: relationships between work environment, Indoor Air Quality, and occupational stress. Indoor Air. 2015;25:499–511.CrossRefPubMed
29.
go back to reference Ohura T, Amagai T, Senga Y, Fusaya M. Organic air pollutants inside and outside residences in Shimizu, Japan: levels, sources and risks. Sci Total Environ. 2006;366:485–99.CrossRefPubMed Ohura T, Amagai T, Senga Y, Fusaya M. Organic air pollutants inside and outside residences in Shimizu, Japan: levels, sources and risks. Sci Total Environ. 2006;366:485–99.CrossRefPubMed
30.
go back to reference Pegas PN, Alves CA, Evtyugina MG, Nunes T, Cerqueira M, Franchi M, et al. Seasonal evaluation of outdoor/indoor air quality in primary schools in Lisbon. J Environ Monit. 2011;13:657–67.CrossRefPubMed Pegas PN, Alves CA, Evtyugina MG, Nunes T, Cerqueira M, Franchi M, et al. Seasonal evaluation of outdoor/indoor air quality in primary schools in Lisbon. J Environ Monit. 2011;13:657–67.CrossRefPubMed
31.
go back to reference Uchiyama S, Tomizawa T, Tokoro A, Aoki M, Hishiki M, Yamada T, et al. Gaseous chemical compounds in indoor and outdoor air of 602 houses throughout Japan in winter and summer. Environ Res. 2015;137:364–72.CrossRefPubMed Uchiyama S, Tomizawa T, Tokoro A, Aoki M, Hishiki M, Yamada T, et al. Gaseous chemical compounds in indoor and outdoor air of 602 houses throughout Japan in winter and summer. Environ Res. 2015;137:364–72.CrossRefPubMed
32.
go back to reference Azuma K, Ikeda K, Osawa H, Kagi N, Yanagi U, Shimodaira T. Questionnaire survey on indoor air quality and maintenance of sanitary environment in buildings. Proceedings of the 12th International Conference on Indoor Air Quality and Climate 2011, Austin, USA, Paper 248, 6 p. Azuma K, Ikeda K, Osawa H, Kagi N, Yanagi U, Shimodaira T. Questionnaire survey on indoor air quality and maintenance of sanitary environment in buildings. Proceedings of the 12th International Conference on Indoor Air Quality and Climate 2011, Austin, USA, Paper 248, 6 p.
33.
go back to reference USEPA. A standardized EPA protocol for characterizing indoor air quality in large office buildings. Washington: Environmental Protection Agency; 2003. USEPA. A standardized EPA protocol for characterizing indoor air quality in large office buildings. Washington: Environmental Protection Agency; 2003.
34.
go back to reference Andersson K. Epidemiological approach to indoor air problems. Indoor Air. 1998;8 Suppl 4:32–9.CrossRef Andersson K. Epidemiological approach to indoor air problems. Indoor Air. 1998;8 Suppl 4:32–9.CrossRef
35.
go back to reference Shimomitsu T, Ohno H, Maruta T, Tanigawa T. Investigation research report concerning prevention of disease related to work in 1997 the Ministry of Labor: III Stress Measurement Research Group Report. Tokyo: Tokyo Medical University; 2000. p. 101–69. in Japanese. Shimomitsu T, Ohno H, Maruta T, Tanigawa T. Investigation research report concerning prevention of disease related to work in 1997 the Ministry of Labor: III Stress Measurement Research Group Report. Tokyo: Tokyo Medical University; 2000. p. 101–69. in Japanese.
36.
go back to reference Wada K, Sairenchi T, Haruyama Y, Taneichi H, Ishikawa Y, Muto T. Relationship between the onset of depression and stress response measured by the brief job stress questionnaire among Japanese employees: a cohort study. PLoS One. 2013;8:e56319.CrossRefPubMedPubMedCentral Wada K, Sairenchi T, Haruyama Y, Taneichi H, Ishikawa Y, Muto T. Relationship between the onset of depression and stress response measured by the brief job stress questionnaire among Japanese employees: a cohort study. PLoS One. 2013;8:e56319.CrossRefPubMedPubMedCentral
37.
go back to reference Dormann CF, Elith J, Bacher S, Buchmann C, Carl G, Carré G, et al. Collinearity: a review of methods to deal with it and a simulation study evaluating their performance. Ecography. 2013;36:27–46.CrossRef Dormann CF, Elith J, Bacher S, Buchmann C, Carl G, Carré G, et al. Collinearity: a review of methods to deal with it and a simulation study evaluating their performance. Ecography. 2013;36:27–46.CrossRef
38.
go back to reference Nafiu OO, Onyewuche V. Association of abdominal obesity in children with perioperative respiratory adverse events. J Perianesth Nurs. 2014;29:84–93.CrossRefPubMed Nafiu OO, Onyewuche V. Association of abdominal obesity in children with perioperative respiratory adverse events. J Perianesth Nurs. 2014;29:84–93.CrossRefPubMed
39.
go back to reference Hosmer DW, Hosmer T, Cessie SL, Lemeshow S. A comparison of goodness-of-fit tests for the logistic regression model. Stat Med. 1997;16:965–80.CrossRefPubMed Hosmer DW, Hosmer T, Cessie SL, Lemeshow S. A comparison of goodness-of-fit tests for the logistic regression model. Stat Med. 1997;16:965–80.CrossRefPubMed
40.
go back to reference Brightman HS, Milton DK, Wypij D, Burge HA, Spengler JD. Evaluating building-related symptoms using the US EPA BASE study results. Indoor Air. 2008;18:335–45.CrossRefPubMed Brightman HS, Milton DK, Wypij D, Burge HA, Spengler JD. Evaluating building-related symptoms using the US EPA BASE study results. Indoor Air. 2008;18:335–45.CrossRefPubMed
41.
go back to reference Reinikainen LM, Jaakkola JJK, Seppaenen O. The effect of air humidification on symptoms and perception of indoor air quality in office workers: a six-period cross-over trial. Arch Environ Health. 1992;47:8–15.CrossRefPubMed Reinikainen LM, Jaakkola JJK, Seppaenen O. The effect of air humidification on symptoms and perception of indoor air quality in office workers: a six-period cross-over trial. Arch Environ Health. 1992;47:8–15.CrossRefPubMed
42.
go back to reference Reinikainen LM, Jaakkola JJK. Significance of humidity and temperature on skin and upper airway symptoms. Indoor Air. 2003;13:344–52.CrossRefPubMed Reinikainen LM, Jaakkola JJK. Significance of humidity and temperature on skin and upper airway symptoms. Indoor Air. 2003;13:344–52.CrossRefPubMed
43.
go back to reference Sunwoo Y, Chou C, Takeshita J, Murakami M, Tochihara Y. Physiological and subjective responses to low relative humidity. J Physiol Anthropol. 2006;25:7–14.CrossRefPubMed Sunwoo Y, Chou C, Takeshita J, Murakami M, Tochihara Y. Physiological and subjective responses to low relative humidity. J Physiol Anthropol. 2006;25:7–14.CrossRefPubMed
44.
go back to reference Sunwoo Y, Chou C, Takeshita J, Murakami M, Tochihara Y. Physiological and subjective responses to low relative humidity in young and elderly men. J Physiol Anthropol. 2006;25:229–38.CrossRefPubMed Sunwoo Y, Chou C, Takeshita J, Murakami M, Tochihara Y. Physiological and subjective responses to low relative humidity in young and elderly men. J Physiol Anthropol. 2006;25:229–38.CrossRefPubMed
45.
go back to reference Ministry of the Environment. Annual Report on the Environment in Japan 2006. Tokyo: Environmental Strategy Division, Environmental Policy Bureau, Ministry of the Environment; 2006. Ministry of the Environment. Annual Report on the Environment in Japan 2006. Tokyo: Environmental Strategy Division, Environmental Policy Bureau, Ministry of the Environment; 2006.
46.
go back to reference Fanger PO. Thermal comfort. Analysis and applications in environmental engineering. New York: McGraw-Hill; 1970. Fanger PO. Thermal comfort. Analysis and applications in environmental engineering. New York: McGraw-Hill; 1970.
47.
go back to reference Ishii A, Iwamoto S, Yamashita M, Katayama T, Shiotsuki Y. An experimental study on the effect of humidity on thermal sensations of people in summer. J Therm Biol. 1994;18:387–91.CrossRef Ishii A, Iwamoto S, Yamashita M, Katayama T, Shiotsuki Y. An experimental study on the effect of humidity on thermal sensations of people in summer. J Therm Biol. 1994;18:387–91.CrossRef
48.
go back to reference Lu CY, Lin JM, Chen YY, Chen YC. Building-related symptoms among office employees associated with indoor carbon dioxide and total volatile organic compounds. Int J Environ Res Public Health. 2015;12:5833–45.CrossRefPubMedPubMedCentral Lu CY, Lin JM, Chen YY, Chen YC. Building-related symptoms among office employees associated with indoor carbon dioxide and total volatile organic compounds. Int J Environ Res Public Health. 2015;12:5833–45.CrossRefPubMedPubMedCentral
49.
go back to reference Glas B, Stenberg B, Stenlund H, Sunesson AL. Exposure to formaldehyde, nitrogen dioxide, ozone, and terpenes among office workers and associations with reported symptoms. Int Arch Occup Environ Health. 2015;88:613–22.CrossRefPubMed Glas B, Stenberg B, Stenlund H, Sunesson AL. Exposure to formaldehyde, nitrogen dioxide, ozone, and terpenes among office workers and associations with reported symptoms. Int Arch Occup Environ Health. 2015;88:613–22.CrossRefPubMed
50.
go back to reference Rios JL, Boechat JL, Gioda A, dos Santos CY, de Aquino Neto FR, Lapa e Silva JR. Symptoms prevalence among office workers of a sealed versus a non-sealed building: associations to indoor air quality. Environ Int. 2009;35:1136–41.CrossRefPubMed Rios JL, Boechat JL, Gioda A, dos Santos CY, de Aquino Neto FR, Lapa e Silva JR. Symptoms prevalence among office workers of a sealed versus a non-sealed building: associations to indoor air quality. Environ Int. 2009;35:1136–41.CrossRefPubMed
51.
go back to reference Ooi PL, Goh KT, Phoon MH, Foo SC, Yap HM. Epidemiology of sick building syndrome and its associated risk factors in Singapore. Occup Environ Med. 1998;55:188–93.CrossRefPubMedPubMedCentral Ooi PL, Goh KT, Phoon MH, Foo SC, Yap HM. Epidemiology of sick building syndrome and its associated risk factors in Singapore. Occup Environ Med. 1998;55:188–93.CrossRefPubMedPubMedCentral
52.
go back to reference Kipen HM, Fiedler N. Environmental factors in medically unexplained symptoms and related syndromes: The evidence and the challenge. Environ Health Perspect. 2002;110 suppl 4:597–9.CrossRefPubMedPubMedCentral Kipen HM, Fiedler N. Environmental factors in medically unexplained symptoms and related syndromes: The evidence and the challenge. Environ Health Perspect. 2002;110 suppl 4:597–9.CrossRefPubMedPubMedCentral
Metadata
Title
Evaluating prevalence and risk factors of building-related symptoms among office workers: Seasonal characteristics of symptoms and psychosocial and physical environmental factors
Authors
Kenichi Azuma
Koichi Ikeda
Naoki Kagi
U Yanagi
Haruki Osawa
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Environmental Health and Preventive Medicine / Issue 1/2017
Print ISSN: 1342-078X
Electronic ISSN: 1347-4715
DOI
https://doi.org/10.1186/s12199-017-0645-4

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