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Respiratory Research
Published in: Respiratory Research 1/2002

Open Access 01-06-2002 | Supplement

Immunoprophylaxis of respiratory syncytial virus: global experience

Author: Eric AF Simoes

Published in: Respiratory Research | Special Issue 1/2002

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Abstract

Respiratory syncytial virus (RSV) infects nearly all children by age 2 years, and it causes considerable illness and death in certain high-risk pediatric populations. Historically, treatment for RSV has been symptomatic, and developing a safe and effective vaccine has been a challenge. Therefore, research efforts have turned to passive immunization as the best option to control RSV. Palivizumab, a genetically engineered humanized monoclonal antibody, has been shown to reduce RSV-related hospitalizations significantly, with few adverse effects. It was approved for use in high-risk children in the USA in 1998 and in Europe in 1999; it is now approved for use in more than 45 countries. The efficacy and safety of palivizumab continue to be supported by both clinical trial and outcomes data.
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Metadata
Title
Immunoprophylaxis of respiratory syncytial virus: global experience
Author
Eric AF Simoes
Publication date
01-06-2002
Publisher
BioMed Central
Published in
Respiratory Research / Issue Special Issue 1/2002
Electronic ISSN: 1465-993X
DOI
https://doi.org/10.1186/rr187

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