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Critical Care
Published in: Critical Care 3/2010

01-06-2010 | Commentary

To dose or not to dose: that is the (starch) question ...

Author: Lewis J Kaplan

Published in: Critical Care | Issue 3/2010

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Abstract

The present study describes the impact on renal function of a modern starch used for resuscitation in the intensive care unit. The role of starch in renal dysfunction, the importance of the definition of acute kidney injury and acute renal failure, and hyperoncoticity are reviewed.
Literature
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Sakr Y, Payen D, Reinhart K, Sipmann FS, Zavala E, Bewley J, Marx G, Vincent JL: Effects of hydroxyethyl starch administration on renal function in critically ill patients. Br J Anaesth 2007, 98: 216-224. 10.1093/bja/ael333CrossRefPubMed
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Schortgen F, Lacherade JC, Bruneel F, Cattaneo I, Hernery F, Lemaire F, Brochard L: Effects of hydroxyethyl starch and gelatin on renal function in severe sepsis: a multicentre randomized study. Lancet 2001, 357: 911-916. 10.1016/S0140-6736(00)04211-2CrossRefPubMed
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Brunkhorst FM, Engel C, Bloos F, Meir-Hellmann A, Ragaller M, Weiler N, Moerer O, Gruendling M, Oppert M, Grond S, Olthoff D, Jaschincki U, John S, Rossaint R, Welte T, Schaefer M, Kern P, Kuhunt E, Kiehntopf M, Hartog C, Nathanson C, Loeffler M, Rainhart K, German Competence Network Sepsis (SepNet): Intensive inslin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med 2008, 358: 125-139. 10.1056/NEJMoa070716CrossRefPubMed
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Metadata
Title
To dose or not to dose: that is the (starch) question ...
Author
Lewis J Kaplan
Publication date
01-06-2010
Publisher
BioMed Central
Published in
Critical Care / Issue 3/2010
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc8973

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