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Critical Care
Published in: Critical Care 4/2007

01-08-2007 | Commentary

Acute kidney injury in the intensive care unit: current trends in incidence and outcome

Authors: Dinna N Cruz, Claudio Ronco

Published in: Critical Care | Issue 4/2007

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Abstract

Acute kidney injury (AKI) is a common clinical problem with significant clinical and economic consequences. A number of studies point to a rising incidence of AKI in the hospital and in the intensive care unit over the past several years, and an increase in the degree of co-morbidity associated with it. Recent evidence suggests that there has been some improvement in outcomes over time. Nevertheless, the mortality associated with AKI remains unacceptably high, and further work is needed. Recently developed consensus definitions will be useful in this regard.
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Ympa YP, Sakr Y, Reinhart K, Vincent JL: Has mortality from acute renal failure decreased? A systematic review of the literature. Am J Med 2005, 118: 827-832. 10.1016/j.amjmed.2005.01.069CrossRefPubMed
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Waikar SS, Curhan GC, Wald R, McCarthy EP, Chertow GM: Declining mortality in patients with acute renal failure, 1988 to 2002. J Am Soc Nephrol 2006, 17: 1143-1150. 10.1681/ASN.2005091017CrossRefPubMed
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Dejavaran P: Emerging biomarkers of acute kidney injury. Contrib Nephrol 2007, 156: 203-212.CrossRef
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Bellomo R, Ronco C, Kellum J, Mehta R, Palevsky P, the ADQI workgroup: Acute renal failure-definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 2004, 8: R204-R2121. 10.1186/cc2872PubMedCentralCrossRefPubMed
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Metadata
Title
Acute kidney injury in the intensive care unit: current trends in incidence and outcome
Authors
Dinna N Cruz
Claudio Ronco
Publication date
01-08-2007
Publisher
BioMed Central
Published in
Critical Care / Issue 4/2007
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc5965

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