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Critical Care
Published in: Critical Care 2/2005

Open Access 01-04-2005 | Research

Coronary artery bypass surgery and longitudinal evaluation of the autonomic cardiovascular function

Authors: Pedro PauloS Soares, Adalgiza M Moreno, Sérgio LD Cravo, Antonio ClaudioL Nóbrega

Published in: Critical Care | Issue 2/2005

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Abstract

Introduction

Imbalance in autonomic cardiovascular function increases the risk for sudden death in patients with coronary artery disease (CAD), but the time course of the impact of coronary artery bypass grafting (CABG) on autonomic function has been little studied. Thus, the purpose of the present study was to determine the effects of the CABG on the cardiovascular autonomic function.

Methods

Patients undergoing CABG (n = 13) and two matched control groups (patients with CAD who refused surgical treatment [n = 9], and healthy volunteers [n = 9]) underwent a prospective longitudinal study consisting of autonomic evaluation before and after (3, 6, 15, 30, 60, and 90 days) surgery, including measurement of heart rate variability (HRV), respiratory sinus arrhythmia (RSA), and Valsalva maneuver.

Results

After CABG there was a decrease in, and a later recovery of, (1) the HRV in the time domain and in the frequency domain, (2) RSA, and (3) Valsalva maneuver.

Conclusions

CABG caused an impairment, reversible after 60 days, of cardiovascular autonomic function, with a maximal decrease on about the sixth day after surgery.
Appendix
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Metadata
Title
Coronary artery bypass surgery and longitudinal evaluation of the autonomic cardiovascular function
Authors
Pedro PauloS Soares
Adalgiza M Moreno
Sérgio LD Cravo
Antonio ClaudioL Nóbrega
Publication date
01-04-2005
Publisher
BioMed Central
Published in
Critical Care / Issue 2/2005
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc3042

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