The burden of high-risk surgery and the potential benefit of goal-directed strategies

Excerpt

The survey by Cannesson and colleagues [1] in the previous issue of Critical Care shows that only around 16% of anesthetists (5.4% of 210 US respondents and 30.4% of 158 European respondents) use a specific treatment protocol (that is, follow a goal-directed strategy) for the peri-operative hemodynamic management of patients undergoing high-risk surgery. In 2008, Weiser and colleagues [2] estimated the global volume of surgery to be 234.2 million procedures a year. According to Pearse and colleagues [3], high-risk surgical procedures represent around 12.5% of this total. A meta-analysis of the 29 randomized controlled trials investigating the value of peri-operative goal-directed strategies reported an average mortality rate of 9.4% in control groups and a significantly reduced mortality rate of 5.9% when a goal-directed strategy was adopted [4]. When putting all the pieces of this puzzle together, one can estimate that around 860,000 lives could potentially be saved every year (the equivalent of one life every 37 seconds) if such strategies became the standard of care around the world (Table 1). …