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Breast Cancer Research
Published in: Breast Cancer Research 2/2003

01-04-2003 | Review

Is there a role for Notch signalling in human breast cancer?

Authors: Keith Brennan, Anthony MC Brown

Published in: Breast Cancer Research | Issue 2/2003

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Abstract

Aberrant Notch signalling has been observed in several human cancers, including acute T-cell lymphoblastic leukaemia and cervical cancer, and is strongly implicated in tumourigenesis. Unregulated Notch signalling in the mouse mammary gland leads to tumour formation. These results raise the possibility that Notch signalling might play a role in human breast cancer. There are currently few reports that address this question directly and this appears to be an area worthy of further investigation.
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Metadata
Title
Is there a role for Notch signalling in human breast cancer?
Authors
Keith Brennan
Anthony MC Brown
Publication date
01-04-2003
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue 2/2003
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr559

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