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Breast Cancer Research
Published in: Breast Cancer Research 1/2001

01-02-2001 | Review

The role of bisphosphonates in breast cancer: The present and future role of bisphosphonates in the management of patients with breast cancer

Authors: Janet E Brown, Robert E Coleman

Published in: Breast Cancer Research | Issue 1/2001

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Abstract

At least 25% of patients with breast cancer develop skeletal metastases, with bone the site of disease producing the greatest morbidity. It is apparent that the bisphosphonates present an important component of the treatment strategy. They are now the treatment of choice in tumour-induced hypercalcaemia, and they can reduce bone pain and skeletal complications such as pathological fractures. In addition, bisphosphonates are being increasingly evaluated in the prevention of bone metastases and to prevent and treat cancer therapy-induced osteoporosis. Ongoing research is aimed at trying to define the optimum route, dose, schedule and type of bisphosphonate.
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Metadata
Title
The role of bisphosphonates in breast cancer: The present and future role of bisphosphonates in the management of patients with breast cancer
Authors
Janet E Brown
Robert E Coleman
Publication date
01-02-2001
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue 1/2001
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr413

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