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Published in: Breast Cancer Research 2/2008

01-05-2008 | Oral presentation

Development of breast cancer immunotherapy using MUC1-retargeted T lymphocytes

Authors: S Wilkie, G Picco, J Foster, D Davies, S Julien, L Cooper, S Arif, S Mather, J Taylor-Papadimitriou, J Burchell, J Maher

Published in: Breast Cancer Research | Special Issue 2/2008

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Excerpt

MUC1 is a highly attractive target for immunotherapy of breast cancer owing to its overexpression, altered glycosylation and loss of polarity in over 90% of tumours. To exploit this, we are developing genetic approaches to retarget T-cell specificity to MUC1 using chimeric antigen receptor (CAR) technology. …
Metadata
Title
Development of breast cancer immunotherapy using MUC1-retargeted T lymphocytes
Authors
S Wilkie
G Picco
J Foster
D Davies
S Julien
L Cooper
S Arif
S Mather
J Taylor-Papadimitriou
J Burchell
J Maher
Publication date
01-05-2008
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue Special Issue 2/2008
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr1881

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