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Breast Cancer Research
Published in: Breast Cancer Research 1/2000

01-03-2000 | Meeting abstract

Role of the breast cancer susceptibility gene BRCA1 in radio-resistance

Authors: V Sylvain, Y-J Bignon

Published in: Breast Cancer Research | Special Issue 1/2000

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Excerpt

Evidence that BRCA1 is involved in DNA repair stems from its interaction with proteins like RAD51, RAD50, etc. We hypothesised that overexpression or antisense inhibition of the mouse homologue Brca1 in an ovarian cancer cell line could result in changes of sensitivity to γ-radiation. …
Metadata
Title
Role of the breast cancer susceptibility gene BRCA1 in radio-resistance
Authors
V Sylvain
Y-J Bignon
Publication date
01-03-2000
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue Special Issue 1/2000
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr159

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Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

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Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine
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