Published in:
01-06-2005 | Oral Presentation
Molecular profiling of early breast cancer in relation to detection of micrometastases and outcome
Authors:
B Naume, T Sørlie
Published in:
Breast Cancer Research
|
Special Issue 2/2005
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Excerpt
Molecular profiling of breast cancer by DNA microarrays has been used to classify tumors into five distinct subclasses that show significant differences in clinical outcomes. Of these subclasses, the luminal subtype A is associated with a relatively good prognosis [
1‐
3]. Detection of disseminated tumor cells (DTC) in bone marrow (BM) can independently predict future metastasis, which was confirmed in our study of 817 early BrCa patients [
4]. …