Published in:
01-06-2005 | Poster Presentation
Gene expression profiling in breast cancer challenges the existence of intermediate histological grade
Authors:
C Sotiriou, P Wirapati, S Loi, A Harris, J Bergh, J Smeds, V Praz, P Farmer, B Haibe-Kains, F Lallemand, M Buyse, M Piccart, M Delorenzi
Published in:
Breast Cancer Research
|
Special Issue 2/2005
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Excerpt
The histological grade (HG) in breast cancer provides important prognostic information. However, its interobserver variability and poor reproducibility, especially for tumours of intermediate grade, have limited its clinical potential. We hypothesized that molecular characterization of the grade may allow for full exploitation of the association between the grade and relapse beyond the ability of traditional grading procedures. …