Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 1/2012

Open Access 01-12-2012 | Poster presentation

The association of autoantibodies expression, Th1/Th2 cytokines balance and IFNG polymorphism with histological phenotype of lupusnephritis

Authors: Kusworini Handono, Atma Gunawan, Singgih Wahono, Rulli Rosandi, Wivina, Natalina Mallo, Handono Kalim

Published in: Arthritis Research & Therapy | Special Issue 1/2012

Login to get access

Excerpt

Racial differences were observed in clinical, serologic and histologic presentation of lupus nephritis (LN)[1]. It has been suggested that Th1/Th2 cytokines balance and IFNG polymorphism play important role in the development of different pathologic pattern of lupus nephritis (LN )[2‐4]. The objective of our study is to determine the association between autoantibodies expression, Th1/Th2 cytokines balance and IFNG polymorphisms with pathologic class of LN in Javanese patients. …
Literature
1.
Korbet SM, Schwartz MM, Evans J, et al: Severe lupus nephritis: racial differences in presentation and outcome. J Am Soc Nephrol. 2007, 18: 244-254. 10.1681/ASN.2006090992.CrossRefPubMed
2.
Chan RW-Y, Lai FM-M, Li EK-M, et al: Imbalance of Th1/Th2 transcription factors in patients with lupus nephritis. Rheumatol. 2006, 45: 951-957. 10.1093/rheumatology/kel029.CrossRef
3.
Miyake K, Nakashima H, Inoue Y, et al: Genetically determined interferon-γ production influences the histological phenotype of lupus nephritis. Rheumatol. 2002, 41: 518-24. 10.1093/rheumatology/41.5.518.CrossRef
4.
Uhm WS, Na K, Song G-W, Jung SS, Lee T, Park MH, Yoo DH: Cytokine balance in kidney tissue from lupus nephiritis patients. Rheumatol. 2003, 42: 935-938. 10.1093/rheumatology/keg255.CrossRef
Metadata
Title
The association of autoantibodies expression, Th1/Th2 cytokines balance and IFNG polymorphism with histological phenotype of lupusnephritis
Authors
Kusworini Handono
Atma Gunawan
Singgih Wahono
Rulli Rosandi
Wivina
Natalina Mallo
Handono Kalim
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue Special Issue 1/2012
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar3681

Other articles of this Special Issue 1/2012

Arthritis Research & Therapy 1/2012 Go to the issue

Oral presentation

Innate and adaptive immune responses to dead and dying cells

Poster presentation

PTEN in antigen presenting cells is a master regulator for Th17-mediated autoimmune pathology

Oral presentation

Signal transduction inhibitors for the treatment of rheumatoid arthritis

Poster presentation

Intermittent cold stress-induced experimental fibromyalgia model in mice - pharmacology and neurobiology

Oral presentation

Abnormal osteogenesis in osteoarthritis: gone with the Wnt?

Poster presentation

Cartilage-specific deletion of prar-gamma in mice results in early endochondral ossification defects and accelerated aging-dependent development of osteoarthritis
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits