Published in:
Open Access
01-12-2012 | Poster presentation
Two cases of multiple-drug-resistant adult-onset Still's disease treated successfully with tocilizumab - the relationship between interleukin 6 and 18
Authors:
Kojiro Sato, Akinori Yamamoto, Yoshihiro Yoshida, Toshihide Mimura
Published in:
Arthritis Research & Therapy
|
Special Issue 1/2012
Login to get access
Excerpt
Adult-onset Still's disease (AOSD) is an inflammatory disease of unknown cause characterized by a high spiking fever, arthritis and evanescent rash. The mainstay of treatment is glucocorticoids with or without immunosuppressants. Recently, biologics such as anti-tumor necrosis factor (TNF) antibodies have also been tried in certain refractory cases. …