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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 1/2012

Open Access 01-12-2012 | Poster presentation

SPACIA1/SAAL1: a newly identified gene associated with aberrant proliferation of synovial fibroblasts

Authors: Tomoo Sato, Ryoji Fujii, Koji Konomi, Naoko Yagishita, Satoko Aratani, Natsumi Araya, Hiroyuki Aono, Kazuo Yudoh, Noboru Suzuki, Moroe Beppu, Yoshihisa Yamano, Kusuki Nishioka, Toshihiro Nakajima

Published in: Arthritis Research & Therapy | Special Issue 1/2012

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Excerpt

The bone and cartilage destruction seen inrheumatoid arthritis (RA) is caused by synovial pannus formation, which is characterized by aberrant proliferation of synovial fibroblasts. Inhibition of synovial proliferation has recently been reported to be a promising therapeutic strategy for RA.However, the specific mechanism underlyingdysregulated proliferation of synovial fibroblasts remains unclear. …
Metadata
Title
SPACIA1/SAAL1: a newly identified gene associated with aberrant proliferation of synovial fibroblasts
Authors
Tomoo Sato
Ryoji Fujii
Koji Konomi
Naoko Yagishita
Satoko Aratani
Natsumi Araya
Hiroyuki Aono
Kazuo Yudoh
Noboru Suzuki
Moroe Beppu
Yoshihisa Yamano
Kusuki Nishioka
Toshihiro Nakajima
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue Special Issue 1/2012
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar3662

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