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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 1/2012

Open Access 01-12-2012 | Poster presentation

Neutrophils are the source of IL-17 and RANKL in zymosan induced arthritis

Authors: Viktoriya I Milanova, Nina D Ivanovska, Petya A Dimitrova

Published in: Arthritis Research & Therapy | Special Issue 1/2012

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Excerpt

Rheumatoid arthritis (RA) is a systemic inflammatory disease affecting cartilage and bone. Recently, much attention on the role of neutrophils in the pathology of RA has been paid. However, the capability of RA neutrophils from periphery and bone marrow (BM) to produce cytokines like IL-17 and IFN-γ has not been well understood. Our aim is to analyze neutrophil distribution in BM, blood and synovium and to elucidate IL-17, IL-4 and IFN-γ production and surface expression of RANKL on peripheral and synovial neutrophils during the progression of zymosan-induced arthritis (ZIA). …
Metadata
Title
Neutrophils are the source of IL-17 and RANKL in zymosan induced arthritis
Authors
Viktoriya I Milanova
Nina D Ivanovska
Petya A Dimitrova
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue Special Issue 1/2012
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar3647

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