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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 1/2012

Open Access 01-12-2012 | Poster presentation

Association between serum level of Vitamin D with autoantibodies expression, disease activity (SLEDAI) and bone mineral density (BMD) in patients with Systemic Lupus Erythematosus (SLE)

Authors: Handono Kalim, Singgih Wahono, Putra Suryana BP, Lenny Puspitasari, Fajar Hadi Wijayanto, Kusworini Handono

Published in: Arthritis Research & Therapy | Special Issue 1/2012

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Excerpt

Vitamin D defficiency has been reported to have negative association with clinical manifestation and disease activity of SLE [1, 2]. Vit D has an important role in the pathogenesis of SLE [3] and it is necessary to give vit D supplementation to the patients [4]. The objective of our study was to determine the association between serum vitamin D level with auto antibodies expression, disease activity and bone mineral density in SLE patients. …
Literature
1.
Toloza SM, Cle DE, Gladman DD, Ibanez D, Urowitz MB: Vitamin D insufficiency in large female cohort. Lupus. 2010, 19: 13-19. 10.1177/0961203309345775.CrossRefPubMed
2.
Ruiz-Irastorza G, Egurbide MV, Olivares N, Martinez-Berriotxoa A, Aguirre C: Vitamin D deficiency in sustemic lupus erythematosus: prevalence, predictor and clinical consequences. Rheumatology. 2008, 47: 920-923. 10.1093/rheumatology/ken121.CrossRefPubMed
3.
Arnson Y, Amital H, Shoenfeld Y: Vitamin D and autoimmunity: new aetiological and therapeutic considerations. Ann Rheum. 2007, 66: 1137-1142. 10.1136/ard.2007.069831.CrossRef
4.
Amital H, Szekanecz Z, Szucs G, et al: Serum concentration of 25-OH vitamin D in patients with systemic lupus erythematosus (SLE) are inversely related to disease activity: is it time to routinely supplement patients with SLE with vitamin D?. Ann Rheum Dis. 2010, 69: 1155-1157. 10.1136/ard.2009.120329.CrossRefPubMed
Metadata
Title
Association between serum level of Vitamin D with autoantibodies expression, disease activity (SLEDAI) and bone mineral density (BMD) in patients with Systemic Lupus Erythematosus (SLE)
Authors
Handono Kalim
Singgih Wahono
Putra Suryana BP
Lenny Puspitasari
Fajar Hadi Wijayanto
Kusworini Handono
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue Special Issue 1/2012
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar3624

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