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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 1/2012

Open Access 01-12-2012 | Poster presentation

Increased concentration of serum soluble LAG3 in systemic lupus erythematosus

Authors: Seri Yu, Keishi Fujio, Kazuyoshi Ishigaki, Hirofumi Shoda, Tomohisa Okamura, Tanita Noor, Shuji Sumitomo, Kazuhiko Yamamoto

Published in: Arthritis Research & Therapy | Special Issue 1/2012

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Excerpt

In systemic lupus erythematosus (SLE), type I interferon and plasmacytoid DCs (pDCs) are supposed to play important roles. However, there are few evidences for pDCs activation in SLE. Murine pDCs are reported to produce soluble LAG3 (sLAG3) upon activation and pDCs are responsible for most of sLAG3 in mice serum [1]. Therefore, serum sLAG3 concentration was examined in SLE and other autoimmune diseases. …
Metadata
Title
Increased concentration of serum soluble LAG3 in systemic lupus erythematosus
Authors
Seri Yu
Keishi Fujio
Kazuyoshi Ishigaki
Hirofumi Shoda
Tomohisa Okamura
Tanita Noor
Shuji Sumitomo
Kazuhiko Yamamoto
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue Special Issue 1/2012
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar3617

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