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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 4/2008

01-08-2008 | Review

Biology and therapy of fibromyalgia. Evidence-based biomarkers for fibromyalgia syndrome

Authors: Dina Dadabhoy, Leslie J Crofford, Michael Spaeth, I Jon Russell, Daniel J Clauw

Published in: Arthritis Research & Therapy | Issue 4/2008

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Abstract

Researchers studying fibromyalgia strive to identify objective, measurable biomarkers that may identify susceptible individuals, may facilitate diagnosis, or that parallel activity of the disease. Candidate objective measures range from sophisticated functional neuroimaging to office-ready measures of the pressure pain threshold. A systematic literature review was completed to assess highly investigated, objective measures used in fibromyalgia studies. To date, only experimental pain testing has been shown to coincide with improvements in clinical status in a longitudinal study. Concerted efforts to systematically evaluate additional objective measures in research trials will be vital for ongoing progress in outcome research and translation into clinical practice.
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Metadata
Title
Biology and therapy of fibromyalgia. Evidence-based biomarkers for fibromyalgia syndrome
Authors
Dina Dadabhoy
Leslie J Crofford
Michael Spaeth
I Jon Russell
Daniel J Clauw
Publication date
01-08-2008
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue 4/2008
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar2443

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