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Health Economics Review
Published in: Health Economics Review 1/2012

Open Access 01-12-2012 | Research

Budgetary impact analysis of buprenorphine-naloxone combination (Suboxone®) in Spain

Authors: Jose Martinez-Raga, Francisco Gonzalez-Saiz, Julian Oñate, Itziar Oyagüez, Eliazar Sabater, Miguel A Casado

Published in: Health Economics Review | Issue 1/2012

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Abstract

Background

Opioid addiction is a worldwide problem. Agonist opioid treatment (AOT) is the most widespread and frequent pharmacotherapeutic approach. Methadone has been the most widely used AOT, but buprenorphine, a partial μ-opiod agonist and a κ-opiod antagonist, is fast gaining acceptance. The objective was to assess the budgetary impact in Spain of the introduction of buprenorphine-naloxone (B/N) combination.

Methods

A budgetary impact model was developed to estimate healthcare costs of the addition of B/N combination to the therapeutic arsenal for treating opioid dependent patients, during a 3-year period under the National Health System perspective. Inputs for the model were obtained from the specialized scientific literature. Detailed information concerning resource consumption (drug cost, logistics, dispensing, medical, psychiatry and pharmacy supervision, counselling and laboratory test) was obtained from a local expert panel. Costs are expressed in euros (€, 2010).

Results

The number of patients estimated to be prescribed B/N combination was 2,334; 2,993 and 3,589 in the first, second and third year respectively. Total budget is €85,766,129; €79,855,471 and €79,137,502 in the first, second and third year for the scenario without B/N combination. With B/N combination the total budget would be €86,589,210; €80,398,259 and €79,708,964 in the first, second and third year of the analyses. Incremental cost/patient comparing the addition of the B/N combination to the scenario only with methadone is €10.58; €6.98 and €7.34 in the first, second and third year respectively.

Conclusion

Addition of B/N combination would imply a maximum incremental yearly cost of €10.58 per patient compared to scenario only with methadone and would provide additional benefits.
Appendix
Available only for authorised users
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Metadata
Title
Budgetary impact analysis of buprenorphine-naloxone combination (Suboxone®) in Spain
Authors
Jose Martinez-Raga
Francisco Gonzalez-Saiz
Julian Oñate
Itziar Oyagüez
Eliazar Sabater
Miguel A Casado
Publication date
01-12-2012
Publisher
Springer Berlin Heidelberg
Published in
Health Economics Review / Issue 1/2012
Electronic ISSN: 2191-1991
DOI
https://doi.org/10.1186/2191-1991-2-3

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