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Published in: Israel Journal of Health Policy Research 1/2012

Open Access 01-12-2012 | Integrative article

Patterns of globalized reproduction: Egg cells regulation in Israel and Austria

Authors: Carmel Shalev, Gabriele Werner-Felmayer

Published in: Israel Journal of Health Policy Research | Issue 1/2012

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Abstract

Since the successful introduction of in vitro fertilization in 1978, medically assisted reproduction (MAR) has proliferated in multiple clinical innovations. Consequently, egg cells have become an object of demand for both infertility treatment and stem cell research, and this raises complex legal, ethical, social and economic issues.
In this paper we compare how the procurement and use of human egg cells is regulated in two countries: Israel and Austria. Israel is known for its scientific leadership, generous public funding, high utilization and liberal regulation of assisted reproductive technology (ART). Austria lies at the other extreme of the regulatory spectrum in terms of restrictions on reproductive interventions.
In both countries, however, there is a constant increase in the use of the technology, and recent legal developments make egg cells more accessible. Also, in both countries the scarcity of egg cells in concert with the rising demand for donations has led to the emergence of cross-border markets and global 'reproductive tourism' practices. In Israel, in particular, a scandal known as the 'eggs affair' was followed by regulation that allowed egg cell donations from outside the country under certain conditions.
Cross-border markets are developed by medical entrepreneurs, driven by global economic gaps, made possible by trans-national regulatory lacunae and find expression as consumer demand. The transnational practice of egg cell donations indicates the emergence of a global public health issue, but there is a general lack of medical and epidemiological data on its efficacy and safety. We conclude that there is need for harmonisation of domestic laws and formulation of new instruments for international governance.
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Literature
4.
go back to reference Annas GJ: American Bioethics: Crossing Human Rights and Health Law Boundaries. 2005, New York: Oxford University Press, 11. Annas GJ: American Bioethics: Crossing Human Rights and Health Law Boundaries. 2005, New York: Oxford University Press, 11.
5.
go back to reference Rothman BK: Recreating Motherhood. 2000, New Brunswick, NJ: Rutgers University Press, 177. Rothman BK: Recreating Motherhood. 2000, New Brunswick, NJ: Rutgers University Press, 177.
6.
go back to reference Dickenson D: Property in the Body. 2007, Cambridge: Cambridge University PressCrossRef Dickenson D: Property in the Body. 2007, Cambridge: Cambridge University PressCrossRef
7.
go back to reference Waldby C: Oocyte markets: women's reproductive work in embryonic stem cell research. New Genetics and Society. 2008, 27 (1): 19-31. 10.1080/14636770701843576.CrossRef Waldby C: Oocyte markets: women's reproductive work in embryonic stem cell research. New Genetics and Society. 2008, 27 (1): 19-31. 10.1080/14636770701843576.CrossRef
8.
go back to reference Beier H: Die Entdeckung der Eizelle der Säugetiere und des Menschen. Reproduktionsmedizin. 2002, 18: 333-338. 10.1007/s00444-002-0379-6.CrossRef Beier H: Die Entdeckung der Eizelle der Säugetiere und des Menschen. Reproduktionsmedizin. 2002, 18: 333-338. 10.1007/s00444-002-0379-6.CrossRef
9.
go back to reference Krysko DV, Diez-Fraile A, Criel G, Svistunov AA, Vandenabeele P, D'Herde K: Life and death of female gametes during oogenesis and folliculogenesis. Apoptosis. 2008, 13: 1065-1087. 10.1007/s10495-008-0238-1.CrossRefPubMed Krysko DV, Diez-Fraile A, Criel G, Svistunov AA, Vandenabeele P, D'Herde K: Life and death of female gametes during oogenesis and folliculogenesis. Apoptosis. 2008, 13: 1065-1087. 10.1007/s10495-008-0238-1.CrossRefPubMed
10.
go back to reference Broekmans FJ, Soules MR, Fauser BC: Ovarian aging: mechanisms and clinical consequences. Endocr Rev. 2009, 30: 465-493. 10.1210/er.2009-0006.CrossRefPubMed Broekmans FJ, Soules MR, Fauser BC: Ovarian aging: mechanisms and clinical consequences. Endocr Rev. 2009, 30: 465-493. 10.1210/er.2009-0006.CrossRefPubMed
11.
go back to reference Nastri CO, Ferriani RA, Rocha IA, Martins WP: Ovarian hyperstimulation syndrome: pathophysiology and prevention. J Assist Reprod Genet. 2010, 27: 121-128. 10.1007/s10815-010-9387-6.PubMedCentralCrossRefPubMed Nastri CO, Ferriani RA, Rocha IA, Martins WP: Ovarian hyperstimulation syndrome: pathophysiology and prevention. J Assist Reprod Genet. 2010, 27: 121-128. 10.1007/s10815-010-9387-6.PubMedCentralCrossRefPubMed
12.
go back to reference Humaidan P, Quartarolo J, Papanikolaou EG: Preventing ovarian hyperstimulation syndrome: guidance for the clinician. Fertil Steril. 2010, 94: 389-400. 10.1016/j.fertnstert.2010.03.028.CrossRefPubMed Humaidan P, Quartarolo J, Papanikolaou EG: Preventing ovarian hyperstimulation syndrome: guidance for the clinician. Fertil Steril. 2010, 94: 389-400. 10.1016/j.fertnstert.2010.03.028.CrossRefPubMed
13.
go back to reference Verberg MFG, Macklon NS, Nargund G, Frydman R, Devroey P, Broekmans FJ, Fauser BCJM: Mild ovarian stimulation for IVF. Hum Reprod. 2009, 15: 13-29.CrossRef Verberg MFG, Macklon NS, Nargund G, Frydman R, Devroey P, Broekmans FJ, Fauser BCJM: Mild ovarian stimulation for IVF. Hum Reprod. 2009, 15: 13-29.CrossRef
18.
go back to reference Dickenson D, Idiakez IA: Ova donation for stem cell research: an international perspective. International Journal of Feminist Approaches to Bioethics. 2008, 1: 125-144. 10.2979/FAB.2008.1.2.125.CrossRef Dickenson D, Idiakez IA: Ova donation for stem cell research: an international perspective. International Journal of Feminist Approaches to Bioethics. 2008, 1: 125-144. 10.2979/FAB.2008.1.2.125.CrossRef
19.
go back to reference Hanna JH, Saha K, Jaenisch R: Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell. 2010, 143: 508-525. 10.1016/j.cell.2010.10.008.PubMedCentralCrossRefPubMed Hanna JH, Saha K, Jaenisch R: Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell. 2010, 143: 508-525. 10.1016/j.cell.2010.10.008.PubMedCentralCrossRefPubMed
20.
go back to reference Carson SA, Eschenbach DA, Lomax G, Rice VM, Sauer MV, Taylor RN, California Institute of Regenerative Medecine advisory committee: Proposed oocyte donation guidelines for stem cell research. Fertil Steril. 2010, 94 (7): 2503-6. 10.1016/j.fertnstert.2009.12.062.CrossRefPubMed Carson SA, Eschenbach DA, Lomax G, Rice VM, Sauer MV, Taylor RN, California Institute of Regenerative Medecine advisory committee: Proposed oocyte donation guidelines for stem cell research. Fertil Steril. 2010, 94 (7): 2503-6. 10.1016/j.fertnstert.2009.12.062.CrossRefPubMed
21.
go back to reference World Health Organization: Genomics and World Health. 2002, Geneva: WHO, 122-172. World Health Organization: Genomics and World Health. 2002, Geneva: WHO, 122-172.
25.
go back to reference de Mouzon J, Goossens V, Bhattacharya S, Castilla JA, Ferraretti AP, Korsak V, Kupka M, Nygren KG, Nyboe Andersen A, European IVF-monitoring (EIM) Consortium, for the European Society of Human Reproduction and Embryology (ESHRE), European IVF-monitoring (EIM) Consortium, for the European Society of Human Reproduction and Embryology (ESHRE): Assisted reproductive technology in Europe, 2006: results generated from European registers by ESHRE. Hum Reprod. 2010, 25: 1851-1862. 10.1093/humrep/deq124.CrossRefPubMed de Mouzon J, Goossens V, Bhattacharya S, Castilla JA, Ferraretti AP, Korsak V, Kupka M, Nygren KG, Nyboe Andersen A, European IVF-monitoring (EIM) Consortium, for the European Society of Human Reproduction and Embryology (ESHRE), European IVF-monitoring (EIM) Consortium, for the European Society of Human Reproduction and Embryology (ESHRE): Assisted reproductive technology in Europe, 2006: results generated from European registers by ESHRE. Hum Reprod. 2010, 25: 1851-1862. 10.1093/humrep/deq124.CrossRefPubMed
27.
go back to reference Collins JA: International survey of the health economics of IVF. Human Reproduction Update. 2002, 8 (3): 265-277. 10.1093/humupd/8.3.265.CrossRefPubMed Collins JA: International survey of the health economics of IVF. Human Reproduction Update. 2002, 8 (3): 265-277. 10.1093/humupd/8.3.265.CrossRefPubMed
28.
go back to reference International Committee for Monitoring Assisted Reproductive Technology, de Mouzon J, Lancaster P, Nygren KG, Sullivan E, Zegers-Hochschild F, Mansour R, Ishihara O, Adamson D: World collaborative report on assisted reproductive technology, 2002. Hum Reprod. 2009, 24: 2310-2320.CrossRef International Committee for Monitoring Assisted Reproductive Technology, de Mouzon J, Lancaster P, Nygren KG, Sullivan E, Zegers-Hochschild F, Mansour R, Ishihara O, Adamson D: World collaborative report on assisted reproductive technology, 2002. Hum Reprod. 2009, 24: 2310-2320.CrossRef
31.
go back to reference Medical Guidelines for IVF Treatment: Recommendations of the Insler Committee. 1998, Jerusalem: Israel Ministry of Health Medical Guidelines for IVF Treatment: Recommendations of the Insler Committee. 1998, Jerusalem: Israel Ministry of Health
32.
go back to reference Shalev C, Gooldin S: The uses and misuses of in-vitro fertilization in Israel: some sociological and ethical considerations. Nashim - Journal of Jewish Women's Studies & Gender Issues. 2006, 12: 151-176.CrossRef Shalev C, Gooldin S: The uses and misuses of in-vitro fertilization in Israel: some sociological and ethical considerations. Nashim - Journal of Jewish Women's Studies & Gender Issues. 2006, 12: 151-176.CrossRef
33.
go back to reference Kahn S: Reproducing Jews. 2000, Durham and London: Duke University Press Kahn S: Reproducing Jews. 2000, Durham and London: Duke University Press
34.
go back to reference Birenbaum-Carmeli D, Carmeli Y: Kin, Gene, Community: Reproductive Technology among Jewish Israelis. 2010, Oxford/New York: Berghahn Books Birenbaum-Carmeli D, Carmeli Y: Kin, Gene, Community: Reproductive Technology among Jewish Israelis. 2010, Oxford/New York: Berghahn Books
35.
go back to reference Public Health (Extra-Corporeal Fertilization) Regulations of 1987. Kovetz Takanot. 1987, 5747; 978 Public Health (Extra-Corporeal Fertilization) Regulations of 1987. Kovetz Takanot. 1987, 5747; 978
36.
go back to reference FH 2401/95 Nahmani v. Nahmani 50 P.D. (4) 661 FH 2401/95 Nahmani v. Nahmani 50 P.D. (4) 661
37.
go back to reference HC 998,2078,2444/96 Weitz et al. v. Minister of Health (unpublished decision of February 2, 1997) HC 998,2078,2444/96 Weitz et al. v. Minister of Health (unpublished decision of February 2, 1997)
39.
go back to reference Eggs Donation Law, 2010. Sefer HaChukkim. 5770; 2242: 520 Eggs Donation Law, 2010. Sefer HaChukkim. 5770; 2242: 520
40.
go back to reference Rabinerson D, Dekel A, Orvieto R, Feldberg D, Simon D, Kaplan B: Subsidised oocyte donation in Israel (1998-2000): results, costs and lessons. Hum Reprod. 2002, 17 (5): 1404-1406. 10.1093/humrep/17.5.1404.CrossRefPubMed Rabinerson D, Dekel A, Orvieto R, Feldberg D, Simon D, Kaplan B: Subsidised oocyte donation in Israel (1998-2000): results, costs and lessons. Hum Reprod. 2002, 17 (5): 1404-1406. 10.1093/humrep/17.5.1404.CrossRefPubMed
43.
go back to reference Joint Committee for the Advancement of Women and Labor and Welfare: Protocol. 2000, per MK Y Dayan (Committee Chair), Israel Joint Committee for the Advancement of Women and Labor and Welfare: Protocol. 2000, per MK Y Dayan (Committee Chair), Israel
45.
go back to reference Public Health (Extra-Corporeal Fertilization) Regulations (Amendment), 2001. Kovetz Takanot. 5762; 277 Public Health (Extra-Corporeal Fertilization) Regulations (Amendment), 2001. Kovetz Takanot. 5762; 277
46.
go back to reference Welfare and Health Committee: Protocol No. 308. 2008, per O. Balaban, Chen Patient Organization, Israel Welfare and Health Committee: Protocol No. 308. 2008, per O. Balaban, Chen Patient Organization, Israel
47.
go back to reference The Prohibition of Genetic Intervention (Human Cloning and Genetic Manipulation of Reproductive Cells) Law, 1999. Sefer HaChukkim. 5759; 47 The Prohibition of Genetic Intervention (Human Cloning and Genetic Manipulation of Reproductive Cells) Law, 1999. Sefer HaChukkim. 5759; 47
48.
go back to reference Israel National Committee for Medical Experiments in Human Beings: Activity Report. Jerusalem. 2003, 6-7. Israel National Committee for Medical Experiments in Human Beings: Activity Report. Jerusalem. 2003, 6-7.
49.
go back to reference Eggs Donation Bill, 2007. Hatza'ot Chok HaMemshalah. 5767; 292 Eggs Donation Bill, 2007. Hatza'ot Chok HaMemshalah. 5767; 292
50.
go back to reference Bernat E: The human right to reproduce non-coitally? A comment on the Austrian constitutional court's judgement of 14 October 1999. Univ Tasman Law Rev. 2002, 21: 20-38.PubMed Bernat E: The human right to reproduce non-coitally? A comment on the Austrian constitutional court's judgement of 14 October 1999. Univ Tasman Law Rev. 2002, 21: 20-38.PubMed
53.
go back to reference Fink S: Ethics vs. innovation? The impact of embryo research laws on the innovative ability of national economies. Science, Technology and Innovation Studies. 2007, 3 (2): 133-149. Fink S: Ethics vs. innovation? The impact of embryo research laws on the innovative ability of national economies. Science, Technology and Innovation Studies. 2007, 3 (2): 133-149.
54.
go back to reference Commission of the European Communities: Commission staff working paper: Report on Human Embryonic Stem Cell Research. 2003, European Commission: Brussels Commission of the European Communities: Commission staff working paper: Report on Human Embryonic Stem Cell Research. 2003, European Commission: Brussels
55.
go back to reference Ferraretti AP, Pennings G, Gianaroli L, Natali F, Magli MC: Cross-border reproductive care: a phenomenon expressing the controversial apects of reproductive technologies. Reprod Biomed Online. 2010, 20: 261-266. 10.1016/j.rbmo.2009.11.009.CrossRefPubMed Ferraretti AP, Pennings G, Gianaroli L, Natali F, Magli MC: Cross-border reproductive care: a phenomenon expressing the controversial apects of reproductive technologies. Reprod Biomed Online. 2010, 20: 261-266. 10.1016/j.rbmo.2009.11.009.CrossRefPubMed
56.
go back to reference Council of Europe: Convention for the Protection of Human Rights and Fundamental Freedoms. 1950, Council of Europe: Strasbourg Council of Europe: Convention for the Protection of Human Rights and Fundamental Freedoms. 1950, Council of Europe: Strasbourg
57.
go back to reference European Court of Human Rights: Application no. 57813/00. Case of S.H. and Others v. Austria. Strasbourg. 2010 European Court of Human Rights: Application no. 57813/00. Case of S.H. and Others v. Austria. Strasbourg. 2010
58.
go back to reference German Act for Protection of Embryos (Embryonenschutzgesetz), 1990. Federal Law Gazette I(69) 2746 German Act for Protection of Embryos (Embryonenschutzgesetz), 1990. Federal Law Gazette I(69) 2746
59.
go back to reference Shalev C: Stem cell tourism - a challenge for trans-national governance. Am J Bioeth. 2010, 10 (5): 40-42. 10.1080/15265161003754049.CrossRefPubMed Shalev C: Stem cell tourism - a challenge for trans-national governance. Am J Bioeth. 2010, 10 (5): 40-42. 10.1080/15265161003754049.CrossRefPubMed
60.
go back to reference Spar D: Reproductive tourism and the regulatory map. New Engl J Med. 2005, 352: 531-533. 10.1056/NEJMp048295.CrossRefPubMed Spar D: Reproductive tourism and the regulatory map. New Engl J Med. 2005, 352: 531-533. 10.1056/NEJMp048295.CrossRefPubMed
64.
go back to reference Ethics Committee Of The American Society For Reproductive Medicine: Financial Compensation of Oocyte Donors. Fertility & Sterility. 2007, 88: 305-309. 10.1016/j.fertnstert.2007.01.104.CrossRef Ethics Committee Of The American Society For Reproductive Medicine: Financial Compensation of Oocyte Donors. Fertility & Sterility. 2007, 88: 305-309. 10.1016/j.fertnstert.2007.01.104.CrossRef
65.
go back to reference Shenfield F, de Mouzon J, Pennings G, Ferraretti AP, Andersen AN, de Wert G, Goossens V, ESHRE Taskforce on Cross Border Reproductive Care: Cross border reproductive care in six European countries. Hum Reprod. 2010, 25: 1361-1368. 10.1093/humrep/deq057.CrossRefPubMed Shenfield F, de Mouzon J, Pennings G, Ferraretti AP, Andersen AN, de Wert G, Goossens V, ESHRE Taskforce on Cross Border Reproductive Care: Cross border reproductive care in six European countries. Hum Reprod. 2010, 25: 1361-1368. 10.1093/humrep/deq057.CrossRefPubMed
66.
go back to reference Nahman M: Nodes of desire: Romanian egg sellers, 'dignity' and feminist alliances in transnational ova exchanges. European Journal of Women's Studies. 2008, 15 (2): 5-82.CrossRef Nahman M: Nodes of desire: Romanian egg sellers, 'dignity' and feminist alliances in transnational ova exchanges. European Journal of Women's Studies. 2008, 15 (2): 5-82.CrossRef
76.
go back to reference Klatsky PC, Delaney SS, Caughey AB, Tran ND, Schattman GL, Rosenwaks Z: The role of embryonic origin in preeclampsia: a comparison of autologous in vitro fertilization and ovum donor pregnancies. Obstet Gynecol. 2010, 116: 1387-1392. 10.1097/AOG.0b013e3181fb8e59.CrossRefPubMed Klatsky PC, Delaney SS, Caughey AB, Tran ND, Schattman GL, Rosenwaks Z: The role of embryonic origin in preeclampsia: a comparison of autologous in vitro fertilization and ovum donor pregnancies. Obstet Gynecol. 2010, 116: 1387-1392. 10.1097/AOG.0b013e3181fb8e59.CrossRefPubMed
77.
go back to reference Pecks U, Maass N, Neulen J: Oocyte donation: a risk factor for pregnancy-induced hypertension - A meta-analysis and case series. Dtsch Arztebl. 2011, 108: 23-31. Pecks U, Maass N, Neulen J: Oocyte donation: a risk factor for pregnancy-induced hypertension - A meta-analysis and case series. Dtsch Arztebl. 2011, 108: 23-31.
Metadata
Title
Patterns of globalized reproduction: Egg cells regulation in Israel and Austria
Authors
Carmel Shalev
Gabriele Werner-Felmayer
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Israel Journal of Health Policy Research / Issue 1/2012
Electronic ISSN: 2045-4015
DOI
https://doi.org/10.1186/2045-4015-1-15

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