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Herpesviridae
Published in: Herpesviridae 1/2011

Open Access 01-12-2011 | Review

Innate immune modulation in EBV infection

Author: Shunbin Ning

Published in: Herpesviridae | Issue 1/2011

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Abstract

Epstein-Barr Virus (EBV) belongs to the gammaherpesvirus family, members of which are oncogenic. Compared with other closely related herpesviruses, EBV has developed much more elaborate and sophisticated strategies for subverting host immune system, which may account for its high prevalence in immune competent hosts. Thus, study of EBV-specific immune dysregulation is important for understanding EBV latency and oncogenesis, and will identify potential molecular targets for immunotherapeutic interventions. Here I summarize the recent findings of individual EBV products in regulating host immune responses, with emphasis on the innate immune modulation.
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Metadata
Title
Innate immune modulation in EBV infection
Author
Shunbin Ning
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Herpesviridae / Issue 1/2011
Electronic ISSN: 2042-4280
DOI
https://doi.org/10.1186/2042-4280-2-1

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