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Clinical and Translational Medicine
Published in: Clinical and Translational Medicine 1/2012

Open Access 01-12-2012 | Editorial

Precision medicine: an approach to R&D for delivering superior medicines to patients

Authors: Mikael Dolsten, Morten Søgaard

Published in: Clinical and Translational Medicine | Issue 1/2012

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Abstract

Pharmaceutical R&D productivity has declined over the last decade despite increasing investments. Recent trends, however, indicate a potential reversal of this trend fueled by a wave of new biologics, vaccines and highly selective NCEs directed against targets validated by human genetics, focus on new disease areas including orphan and genetic diseases and more precise tailoring of medicines to their target populations.
Literature
1.
Desmond-Hellman S: Toward precision medicine: a new social contract? Sci Transl Med 2012, 4(129):1–2.CrossRef
2.
Toward precision medicine: Building a knowledge network for biomedical research and a new taxonomy of disease. The National Academies Press, Washington, DC; 2011.
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Pacanowski MA, Zineh MA: Pharmacogenomic strategies in drug safety. Drug Discov Today: Therapeutic Strategies 2011,:. 10 1016/j.ddstr.2011.04.002
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Metadata
Title
Precision medicine: an approach to R&D for delivering superior medicines to patients
Authors
Mikael Dolsten
Morten Søgaard
Publication date
01-12-2012
Publisher
Springer Berlin Heidelberg
Published in
Clinical and Translational Medicine / Issue 1/2012
Electronic ISSN: 2001-1326
DOI
https://doi.org/10.1186/2001-1326-1-7

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