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Published in: International Journal of Emergency Medicine 1/2011

Open Access 01-12-2011 | Brief Research Report

A protocol for the emergency department management of acute undifferentiated febrile illness in India

Authors: Sudhagar Thangarasu, Piruthiviraj Natarajan, Parivalavan Rajavelu, Arjun Rajagopalan, Jeremy S Seelinger Devey

Published in: International Journal of Emergency Medicine | Issue 1/2011

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Abstract

Background

Fever is a common presenting complaint in the developing world, but there is a paucity of literature to guide investigation and treatment of the adult patient presenting with fever and no localizing symptoms.

Objective

The objective of this study was to devise a standardized protocol for the evaluation and treatment of febrile adult patients who have no localizing symptoms in order to reduce unnecessary testing and inappropriate antimicrobial use. After devising the protocol, a pilot study was performed to assess its feasibility in the emergency department.

Methods

A protocol was formulated for adult patients presenting with fever who had no clinical evidence of sepsis and no localizing symptoms to suggest the etiology of their fever. Investigations were based on duration of fever with no investigations indicated prior to day 3. Treatment was guided by results of investigations. A pilot study was performed after protocol implementation, wherein data were collected on successive adult patients presenting with fever.

Results

During the 6-week study period, 342 patients presented with fever, 209 of whom fit the parameters of the protocol, with 113 of these patients presenting on the 1st or 2nd day of fever. All patients experienced defervescence of fever, with ten patients being lost to follow-up. Of the patients presenting on day 1 or 2 of fever, 75.2% (85/113) defervesced without the need for testing; 53.1% (60/113) experienced defervescence without the need for antimicrobial therapy.

Conclusion

Implementation of this rational, standardized protocol for the assessment and treatment of stable adult patients presenting with acute undifferentiated febrile illness can lead to reduced rates of testing and antimicrobial use. A prospective, controlled trial will be required to confirm these findings and to assess additional safety outcome measures.
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Metadata
Title
A protocol for the emergency department management of acute undifferentiated febrile illness in India
Authors
Sudhagar Thangarasu
Piruthiviraj Natarajan
Parivalavan Rajavelu
Arjun Rajagopalan
Jeremy S Seelinger Devey
Publication date
01-12-2011
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Emergency Medicine / Issue 1/2011
Print ISSN: 1865-1372
Electronic ISSN: 1865-1380
DOI
https://doi.org/10.1186/1865-1380-4-57

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