Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on sleep in brain health

LIVE: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
ADVANCED SEARCH
Log in
Top
Italian Journal of Pediatrics
Published in: Italian Journal of Pediatrics 1/2014

Open Access 01-12-2014 | Research

Italian guidelines for management and treatment of hyperbilirubinaemia of newborn infants ≥ 35 weeks’ gestational age

Published in: Italian Journal of Pediatrics | Issue 1/2014

Login to get access

Abstract

Hyperbilirubinaemia is one of the most frequent problems in otherwise healthy newborn infants. Early discharge of the healthy newborn infants, particularly those in whom breastfeeding is not fully established, may be associated with delayed diagnosis of significant hyperbilirubinaemia that has the potential for causing severe neurological impairments. We present the shared Italian guidelines for management and treatment of jaundice established by the Task Force on hyperbilirubinaemia of the Italian Society of Neonatology.
The overall aim of the present guidelines is to provide an useful tool for neonatologists and family paediatricians for managing hyperbilirubinaemia.
Appendix
Available only for authorised users
Literature
1.
Maisels MJ, Kring E: Length of stay, jaundice, and hospital readmission. Pediatrics. 1998, 101: 995-998. 10.1542/peds.101.6.995.CrossRefPubMed
2.
Friedman MA, Spitzer AR: Discharge criteria for the term newborn. Pediatr Clin North Am. 2004, 51: 599-618. 10.1016/j.pcl.2004.01.011. viiiCrossRefPubMed
3.
Mercier CE, Barry SE, Paul K, Delaney TV, Horbar JD, Wasserman RC, Berry P, Shaw JS: Improving newborn preventive services at the birth hospitalization: a collaborative, hospital-based quality-improvement project. Pediatrics. 2007, 120: 481-488. 10.1542/peds.2007-0233.CrossRefPubMed
4.
Lee KS, Perlman M, Ballantyne M, Elliott I, To T: Association between duration of neonatal hospital stay and readmission rate. J Pediatr. 1995, 127: 758-766. 10.1016/S0022-3476(95)70170-2.CrossRefPubMed
5.
Seidman DS, Stevenson DK, Ergaz Z, Gale R: Hospital readmission due to neonatal hyperbilirubinemia. Pediatrics. 1995, 96: 727-729.PubMed
6.
Dani C, Poggi C, Barp J, Romagnoli C, Buonocore G: Current Italian practices regarding the management of hyperbilirubinaemia in preterm infants. Acta Paediatr. 2011, 100: 666-669. 10.1111/j.1651-2227.2011.02172.x.CrossRefPubMed
7.
American Academy of Pediatrics Subcommittee on H: Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics. 2004, 114: 297-316.CrossRef
8.
Maisels MJ, Bhutani VK, Bogen D, Newman TB, Stark AR, Watchko JF: Hyperbilirubinemia in the newborn infant > or =35 weeks’ gestation: an update with clarifications. Pediatrics. 2009, 124: 1193-1198. 10.1542/peds.2009-0329.CrossRefPubMed
9.
Bhutani VK, Committee on F, Newborn, American Academy of P: Phototherapy to prevent severe neonatal hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics. 2011, 128: e1046-e1052. 10.1542/peds.2011-1494.CrossRefPubMed
10.
11.
Atkinson M, Budge H: Review of the NICE guidance on neonatal jaundice. Arch Dis Child Educ Pract Ed. 2011, 96: 136-140. 10.1136/adc.2010.206755.CrossRefPubMed
12.
Newman J: Guidelines for detection, management and prevention of hyperbilirubinemia in term and late preterm newborn infants (35 or more weeks’ gestation) - Summary. Paediatr Child Health. 2007, 12: 401-418.
13.
van Imhoff DE, Dijk PH, Hulzebos CV, Bartrial study group NNRN: Uniform treatment thresholds for hyperbilirubinemia in preterm infants: background and synopsis of a national guideline. Early Hum Dev. 2011, 87: 521-525. 10.1016/j.earlhumdev.2011.04.004.CrossRefPubMed
14.
Bratlid D, Nakstad B, Hansen TW: National guidelines for treatment of jaundice in the newborn. Acta Paediatr. 2011, 100: 499-505. 10.1111/j.1651-2227.2010.02104.x.CrossRefPubMed
15.
Kaplan M, Merlob P, Regev R: Israel guidelines for the management of neonatal hyperbilirubinemia and prevention of kernicterus. J Perinatol. 2008, 28: 389-397. 10.1038/jp.2008.20.CrossRefPubMed
16.
17.
18.
19.
20.
21.
De Luca D, Romagnoli C, Tiberi E, Zuppa AA, Zecca E: Skin bilirubin nomogram for the first 96 h of life in a European normal healthy newborn population, obtained with multiwavelength transcutaneous bilirubinometry. Acta Paediatr. 2008, 97: 146-150. 10.1111/j.1651-2227.2007.00622.x.CrossRefPubMed
22.
Romagnoli C, Tiberi E, Barone G, De Curtis M, Regoli D, Paolillo P, Picone S, Anania S, Finocchi M, Cardiello V, Zecca E: Validation of transcutaneous bilirubin nomogram in identifying neonates not at risk of hyperbilirubinaemia: a prospective, observational, multicenter study. Early Hum Dev. 2012, 88: 51-55. 10.1016/j.earlhumdev.2011.07.001.CrossRefPubMed
23.
Romagnoli C, Tiberi E, Barone G, Curtis MD, Regoli D, Paolillo P, Picone S, Anania S, Finocchi M, Cardiello V, Giordano L, Paolucci V, Zecca E: Development and validation of serum bilirubin nomogram to predict the absence of risk for severe hyperbilirubinaemia before discharge: a prospective, multicenter study. Ital J Pediatr. 2012, 38: 6-10.1186/1824-7288-38-6.PubMedCentralCrossRefPubMed
24.
25.
Maisels MJ, Watchko JF: Treatment of jaundice in low birthweight infants. Arch Dis Child Fetal Neonatal Ed. 2003, 88 (6): F459-F463. 10.1136/fn.88.6.F459.PubMedCentralCrossRefPubMed
26.
Watchko JF, Maisels MJ: Jaundice in low birthweight infants: pathobiology and outcome. Arch Dis Child Fetal Neonatal Ed. 2003, 88 (6): F455-F458. 10.1136/fn.88.6.F455.PubMedCentralCrossRefPubMed
27.
Moyer VA, Ahn C, Sneed S: Accuracy of clinical judgment in neonatal jaundice. Arch Pediatr Adolesc Med. 2000, 154: 391-394. 10.1001/archpedi.154.4.391.CrossRefPubMed
28.
De Luca D, Zecca E, Zuppa AA, Romagnoli C: The joint use of human and electronic eye: visual assessment of jaundice and transcutaneous bilirubinometry. Turk J Pediatr. 2008, 50: 456-461.PubMed
29.
Riskin A, Tamir A, Kugelman A, Hemo M, Bader D: Is visual assessment of jaundice reliable as a screening tool to detect significant neonatal hyperbilirubinemia?. J Pediatr. 2008, 152: 782-787. 10.1016/j.jpeds.2007.11.003. 787 e781-782CrossRefPubMed
30.
Knudsen A: The influence of the reserve albumin concentration and pH on the cephalocaudal progression of jaundice in newborns. Early Hum Dev. 1991, 25: 37-41. 10.1016/0378-3782(91)90204-G.CrossRefPubMed
31.
32.
Romagnoli C, Catenazzi P, Barone G, Giordano L, Riccardi R, Zuppa AA, Zecca E: BiliCheck vs JM-103 in identifying neonates not at risk of hyperbilirubinaemia. Ital J Pediatr. 2013, 39: 46-10.1186/1824-7288-39-46.PubMedCentralCrossRefPubMed
33.
Romagnoli C, Zecca E, Catenazzi P, Barone G, Zuppa AA: Transcutaneous bilirubin measurement: comparison of Respironics BiliCheck and JM-103 in a normal newborn population. Clin Biochem. 2012, 45: 659-662. 10.1016/j.clinbiochem.2012.03.014.CrossRefPubMed
34.
Bhutani VK, Johnson L, Sivieri EM: Predictive ability of a predischarge hour-specific serum bilirubin for subsequent significant hyperbilirubinemia in healthy term and near-term newborns. Pediatrics. 1999, 103: 6-14. 10.1542/peds.103.1.6.CrossRefPubMed
35.
Yu ZB, Dong XY, Han SP, Chen YL, Qiu YF, Sha L, Sun Q, Guo XR: Transcutaneous bilirubin nomogram for predicting neonatal hyperbilirubinemia in healthy term and late-preterm Chinese infants. Eur J Pediatr. 2011, 170: 185-191. 10.1007/s00431-010-1281-9.CrossRefPubMed
36.
Varvarigou A, Fouzas S, Skylogianni E, Mantagou L, Bougioukou D, Mantagos S: Transcutaneous bilirubin nomogram for prediction of significant neonatal hyperbilirubinemia. Pediatrics. 2009, 124: 1052-1059. 10.1542/peds.2008-2322.CrossRefPubMed
37.
Mills JF, Tudehope D: Fibreoptic phototherapy for neonatal jaundice. Cochrane Database Syst Rev. 2001, 1: CD002060-PubMed
38.
Barak M, Berger I, Dollberg S, Mimouni FB, Mandel D: When should phototherapy be stopped? A pilot study comparing two targets of serum bilirubin concentration. Acta Paediatr. 2009, 98: 277-281.CrossRefPubMed
39.
Kaplan M, Kaplan E, Hammerman C, Algur N, Bromiker R, Schimmel MS, Eidelman AI: Post-phototherapy neonatal bilirubin rebound: a potential cause of significant hyperbilirubinaemia. Arch Dis Child. 2006, 91: 31-34.PubMedCentralCrossRefPubMed
40.
Kemper K, Forsyth B, McCarthy P: Jaundice, terminating breast-feeding, and the vulnerable child. Pediatrics. 1989, 84: 773-778.PubMed
41.
Martinez JC, Maisels MJ, Otheguy L, Garcia H, Savorani M, Mogni B, Martinez JC: Hyperbilirubinemia in the breast-fed newborn: a controlled trial of four interventions. Pediatrics. 1993, 91: 470-473.PubMed
42.
Alcock GS, Liley H: Immunoglobulin infusion for isoimmune haemolytic jaundice in neonates. Cochrane Database Syst Rev. 2002, 3: CD003313-PubMed
43.
Miqdad AM, Abdelbasit OB, Shaheed MM, Seidahmed MZ, Abomelha AM, Arcala OP: Intravenous immunoglobulin G (IVIG) therapy for significant hyperbilirubinemia in ABO hemolytic disease of the newborn. J Matern Fetal Neonatal Med. 2004, 16: 163-166. 10.1080/jmf.16.3.163.166.CrossRefPubMed
Metadata
Title
Italian guidelines for management and treatment of hyperbilirubinaemia of newborn infants ≥ 35 weeks’ gestational age
Publication date
01-12-2014
Published in
Italian Journal of Pediatrics / Issue 1/2014
Electronic ISSN: 1824-7288
DOI
https://doi.org/10.1186/1824-7288-40-11

Other articles of this Issue 1/2014

Italian Journal of Pediatrics 1/2014 Go to the issue

Research

Parenting approaches and digital technology use of preschool age children in a Chinese community

Research

Plant sterols–enriched diet decreases small, dense LDL-cholesterol levels in children with hypercholesterolemia: a prospective study

Research

Analysis of nitric oxide synthase gene polymorphisms in neonatal respiratory distress syndrome among the Chinese Han population

Review

Progress in pediatrics in 2013: choices in allergology, endocrinology, gastroenterology, hypertension, infectious diseases, neonatology, neurology, nutrition and respiratory tract illnesses

Case report

Effect of long-term GH treatment in a patient with CHARGE association

Research

Effect of abdomen massage for prevention of feeding intolerance in preterm infants