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Italian Journal of Pediatrics

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Open Access 01-12-2013 | Research

The effect of IVF pregnancies on mortality and morbidity in tertiary unit

Authors: Gülcan Turker, Emek Doger, Ayşe Engin Arısoy, Ayla Günlemez, Ayşe Sevim Gökalp

Published in: Italian Journal of Pediatrics | Issue 1/2013

Abstract

Background

There are several studies that have shown an increased risk of premature birth and developmental abnormalities with in vitro fertilization (IVF); however, the data on preterm mortality and morbidity are limited.

Aim

Our aim is to investigate whether IVF had an effect on the mortality and morbidity in neonates admitted to the neonatal intensive care unit.

Methods

A total of 940 term and preterm babies who were admitted to the intensive care unit over a period of 2 years were enrolled. Of these, 121 babies were born after IVF and 810 were born after a natural conception and 9 were born after ovulation induction. Of these, 112 preterm babies were born after IVF and 405 preterm babies were born after a natural conception.

Results

In the IVF group, the gestational age and birth weight were significantly lower than in the non-IVF group. Additionally, in the IVF group, multiple births were significantly higher than in the non-IVF group. IVF pregnancies increase preterm delivery but did not increase preterm mortality, and preterm morbidity did not differ among groups, except for intraventricular hemorrhage (IVH). Gestational age was shown to be the primary risk factor for IVH using a logistic regression analysis. Also when newborns at gestational age <32 weeks were compared using regression analysis, gestational age was the major risk factor for IVH.

Conclusion

IVF appears to be associated with premature delivery and the known risks associated with prematurity.

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Title: The effect of IVF pregnancies on mortality and morbidity in tertiary unit
Authors: Gülcan Turker
Emek Doger
Ayşe Engin Arısoy
Ayla Günlemez
Ayşe Sevim Gökalp
Publication date: 01-12-2013
Publisher: BioMed Central
Published in: Italian Journal of Pediatrics / Issue 1/2013
Electronic ISSN: 1824-7288
DOI: https://doi.org/10.1186/1824-7288-39-17

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The effect of IVF pregnancies on mortality and morbidity in tertiary unit

Abstract

Background

Aim

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Aim

Methods

Results

Conclusion

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