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Published in: Diabetology & Metabolic Syndrome 1/2013

Open Access 01-12-2013 | Review

Historical facts of screening and diagnosing diabetes in pregnancy

Authors: Carlos Antonio Negrato, Marilia Brito Gomes

Published in: Diabetology & Metabolic Syndrome | Issue 1/2013

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Abstract

Diabetes is the most common metabolic disorder affecting pregnancy. Its prevalence seems to be growing in parallel with the epidemics of overweight and obesity. Recognizing and treating diabetes or any degree of glucose intolerance in pregnancy results in lowering maternal and fetal complications. These patients present higher risk for excessive weight gain, preeclampsia, cesarean sections, a high risk of developing type 2 diabetes and cardiovascular disease in the future. Infants born to these mothers are at higher risk for macrosomia and birth trauma, and after delivery, these infants have a higher risk of developing hypoglycemia, hypocalcemia, hyperbilirubinemia, respiratory distress syndrome, polycythemia and subsequent obesity and type 2 diabetes. Despite several international workshops and a lot of research there is still no unique approach to diagnose and treat diabetes in pregnancy. Who, when and how to screen and diagnose diabetes in pregnancy has been debated in the literature for so many decades and this debate seems to be endless. We present the evolution that screening and diagnosing diabetes in pregnancy has had over time. Besides many evidence of the benefits these procedures bring, health care providers still often prefer to use alternate criteria for this purpose. The myriad of maternal and fetal complications that could be avoided with an appropriate and simple screening procedure are ignored. Robust clinical trials such as the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study have shown how harmful can even slightly altered blood glucose levels be, but it has been found a resistance in the adoption of the new criteria proposed after this and other trials by many diabetes organizations. These organizations state that these new criteria would increase the incidence of diabetes in pregnancy, would imply in longer term follow-up of these patients and would pose an economic problem; they also state that alerting too many people in order to benefit a relatively few potential diabetics would arise psychologic ill-effects. We think that health care providers should look for an uniformity in the screening and diagnosing diabetes in pregnancy based on evidence based medicine and not on specialists consensus.
Literature
1.
go back to reference Bennewitz HG: De Diabete Mellito, gravidatatis symptomate. 1824, MD Thesis, University of Berlin Bennewitz HG: De Diabete Mellito, gravidatatis symptomate. 1824, MD Thesis, University of Berlin
2.
go back to reference Lever JCW: Guy’s Hospital Report. 1847, London, 3- Lever JCW: Guy’s Hospital Report. 1847, London, 3-
3.
go back to reference Lecorche: Ann de Gynecol et d’obst. 1885, Paris, 257-24 Lecorche: Ann de Gynecol et d’obst. 1885, Paris, 257-24
4.
go back to reference Mestman JH: Historical notes on diabetes and pregnancy. Endocrinologist. 2002, 12: 224-242. 10.1097/00019616-200205000-00010.CrossRef Mestman JH: Historical notes on diabetes and pregnancy. Endocrinologist. 2002, 12: 224-242. 10.1097/00019616-200205000-00010.CrossRef
5.
go back to reference Von Noorden C: Die Die Zuckerkrankheit, Volume 4. 1917, Aufl Von Noorden C: Die Die Zuckerkrankheit, Volume 4. 1917, Aufl
6.
go back to reference Skipper E: Diabetes mellitus in pregnancy: A clinical and analytical study. QJM. 1933, 7: 353-80. Skipper E: Diabetes mellitus in pregnancy: A clinical and analytical study. QJM. 1933, 7: 353-80.
7.
go back to reference Duncan JM: On puerperal diabetes. Trans Obstet Soc Lond. 1882, 24: 256- Duncan JM: On puerperal diabetes. Trans Obstet Soc Lond. 1882, 24: 256-
8.
go back to reference Williams JW: The clinical significance of glycosuria in pregnant women. Am J Med Sci. 1909, 137: 1-26. 10.1097/00000441-190901000-00001.CrossRef Williams JW: The clinical significance of glycosuria in pregnant women. Am J Med Sci. 1909, 137: 1-26. 10.1097/00000441-190901000-00001.CrossRef
9.
10.
go back to reference Hofmeister Ztschr F: Phys Chemie. 1877, 1: 101- Hofmeister Ztschr F: Phys Chemie. 1877, 1: 101-
11.
go back to reference Brocard: La glycosuria de al groaesser. 1898, These de Paris Brocard: La glycosuria de al groaesser. 1898, These de Paris
12.
go back to reference Dubreuil G, Anderodias : Compt Rendus Soc Biol. 1920, 133: 1490- Dubreuil G, Anderodias : Compt Rendus Soc Biol. 1920, 133: 1490-
13.
go back to reference Walker A: Diabetes mellitus in pregnancy. Proc Roy Soc Med. 1927–1928, xxi: 13- Walker A: Diabetes mellitus in pregnancy. Proc Roy Soc Med. 1927–1928, xxi: 13-
14.
go back to reference Graham G: A case of diabetes mellitus complicated by pregnancy treated with insulin. Proc Roy Soc Med. 1924, xvii: 102-104. Graham G: A case of diabetes mellitus complicated by pregnancy treated with insulin. Proc Roy Soc Med. 1924, xvii: 102-104.
15.
go back to reference Reveno WS: Insulin in diabetic coma complicating pregnancy. JAMA. 1923, 81: 2001-2002.CrossRef Reveno WS: Insulin in diabetic coma complicating pregnancy. JAMA. 1923, 81: 2001-2002.CrossRef
16.
go back to reference Lambie CG: Diabetes and pregnancy. J Obstet Gynecol Br Emp. 1926, 33: 563-606. 10.1111/j.1471-0528.1926.tb12131.x.CrossRef Lambie CG: Diabetes and pregnancy. J Obstet Gynecol Br Emp. 1926, 33: 563-606. 10.1111/j.1471-0528.1926.tb12131.x.CrossRef
17.
go back to reference Miller HC: The effect of the prediabetic state on the survival of the fetus and the birth weight of the newborn infant. N Engl J Med. 1945, 233: 376-378. 10.1056/NEJM194509272331302.CrossRef Miller HC: The effect of the prediabetic state on the survival of the fetus and the birth weight of the newborn infant. N Engl J Med. 1945, 233: 376-378. 10.1056/NEJM194509272331302.CrossRef
18.
go back to reference Moss JM, Mullholand HB: Diabetes and pregnancy with special reference to the prediabetic state. Ann Intern Med. 1951, 34: 678-691.CrossRefPubMed Moss JM, Mullholand HB: Diabetes and pregnancy with special reference to the prediabetic state. Ann Intern Med. 1951, 34: 678-691.CrossRefPubMed
19.
go back to reference Wilkerson HLC, Remein QR: Studies of abnormal carbohydrate metabolism in pregnancy. Diabetes. 1957, 6: 324-329.CrossRefPubMed Wilkerson HLC, Remein QR: Studies of abnormal carbohydrate metabolism in pregnancy. Diabetes. 1957, 6: 324-329.CrossRefPubMed
20.
go back to reference Carrington ER, Shuman CR, Rearson HS: Evaluation of the prediabetic state during pregnancy. Obstet Gynecol. 1957, 9: 664-669. 10.1097/00006250-195706000-00008.CrossRefPubMed Carrington ER, Shuman CR, Rearson HS: Evaluation of the prediabetic state during pregnancy. Obstet Gynecol. 1957, 9: 664-669. 10.1097/00006250-195706000-00008.CrossRefPubMed
21.
go back to reference Jackson WPU, Cambridge MA: Diabetes, prediabetes, mothers and babies. S Afr Med J. 1953, 27: 795-797.PubMed Jackson WPU, Cambridge MA: Diabetes, prediabetes, mothers and babies. S Afr Med J. 1953, 27: 795-797.PubMed
22.
23.
go back to reference Hoet JP: Carbohydrate metabolism in pregnancy (translated from the French by F.D.W. Lukens). Diabetes. 1954, 3: 1-12.CrossRefPubMed Hoet JP: Carbohydrate metabolism in pregnancy (translated from the French by F.D.W. Lukens). Diabetes. 1954, 3: 1-12.CrossRefPubMed
24.
go back to reference Knopp RH, John B: O’Sullivan: A Pioneer in the study of gestational diabetes. Diabetes Care. 2002, 25: 943-944. 10.2337/diacare.25.5.943.CrossRefPubMed Knopp RH, John B: O’Sullivan: A Pioneer in the study of gestational diabetes. Diabetes Care. 2002, 25: 943-944. 10.2337/diacare.25.5.943.CrossRefPubMed
26.
go back to reference Unger RH, Madison LL: A new diagnostic procedure for mild diabetes mellitus: evaluations of an intravenous tolbutamide response test. Diabetes. 1958, 7: 455-CrossRefPubMed Unger RH, Madison LL: A new diagnostic procedure for mild diabetes mellitus: evaluations of an intravenous tolbutamide response test. Diabetes. 1958, 7: 455-CrossRefPubMed
27.
go back to reference Conn JW, Fajans SS: The prediabetic state. Am J Med. 1961, 31: 839-850. 10.1016/0002-9343(61)90023-7.CrossRefPubMed Conn JW, Fajans SS: The prediabetic state. Am J Med. 1961, 31: 839-850. 10.1016/0002-9343(61)90023-7.CrossRefPubMed
28.
go back to reference O’Sullivan J, Mahan C: Criteria for the oral glucose tolerance test in pregnancy. Diabetes. 1964, 13: 278-285.PubMed O’Sullivan J, Mahan C: Criteria for the oral glucose tolerance test in pregnancy. Diabetes. 1964, 13: 278-285.PubMed
29.
go back to reference Pedersen J, Brandstrup E: Fetal mortality in pregnant diabetics. Lancet. 1956, 27: 607-610.CrossRef Pedersen J, Brandstrup E: Fetal mortality in pregnant diabetics. Lancet. 1956, 27: 607-610.CrossRef
30.
go back to reference National Diabetes Data Group: Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes. 1979, 28: 1039-1057.CrossRef National Diabetes Data Group: Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes. 1979, 28: 1039-1057.CrossRef
31.
go back to reference Hadden DR: Glucose tolerance tests in pregnancy. Carbohydrate Metabolism in Pregnancy and the Newborn. Edited by: Sutherland HW, Stowers JM. 1975, Edinburgh: Churchill Livingstone, 19-41. Hadden DR: Glucose tolerance tests in pregnancy. Carbohydrate Metabolism in Pregnancy and the Newborn. Edited by: Sutherland HW, Stowers JM. 1975, Edinburgh: Churchill Livingstone, 19-41.
32.
go back to reference Jovanovic L: Gestational Diabetes Mellitus. JAMA. 2001, 286 (20): 2516-2518. 10.1001/jama.286.20.2516.CrossRefPubMed Jovanovic L: Gestational Diabetes Mellitus. JAMA. 2001, 286 (20): 2516-2518. 10.1001/jama.286.20.2516.CrossRefPubMed
33.
go back to reference Freinkel N, Josinovich J: First Workshop Conference on Gestational Diabetes. Diabetes Care. 1980, 3: 399-501.CrossRefPubMed Freinkel N, Josinovich J: First Workshop Conference on Gestational Diabetes. Diabetes Care. 1980, 3: 399-501.CrossRefPubMed
34.
go back to reference Proceedings of the Second International Workshop-Conference on Gestational Diabetes Mellitus. Diabetes. 1985, 34 (S2): 1-130. Proceedings of the Second International Workshop-Conference on Gestational Diabetes Mellitus. Diabetes. 1985, 34 (S2): 1-130.
35.
go back to reference Third International Workshop Conference on Gestational Diabetes Mellitus: Summary and recommendations. Diabetes. 1991, 40 (S2): 197-201. Third International Workshop Conference on Gestational Diabetes Mellitus: Summary and recommendations. Diabetes. 1991, 40 (S2): 197-201.
36.
go back to reference Metzger BE, Coustan DR: Summary and recommendations of the Fourth International Workshop Conference on Gestational Diabetes Mellitus. Diabetes Care. 1998, 21 (suppl 2): B161-B167.PubMed Metzger BE, Coustan DR: Summary and recommendations of the Fourth International Workshop Conference on Gestational Diabetes Mellitus. Diabetes Care. 1998, 21 (suppl 2): B161-B167.PubMed
37.
go back to reference Metzger BE, Buchanan TA, Coustan DR, De Leiva A, Dunger DB, Hadden DR, Hod M, Kitzmiller JL, Kjos SL, Oats JN, Pettitt DJ, Sacks DA, Zoupas C: Summary and Recommendations of the Fifth International Workshop-Conference on Gestational Diabetes Mellitus. Diabetes Care. 2007, 30 (S2): S251-S260.CrossRefPubMed Metzger BE, Buchanan TA, Coustan DR, De Leiva A, Dunger DB, Hadden DR, Hod M, Kitzmiller JL, Kjos SL, Oats JN, Pettitt DJ, Sacks DA, Zoupas C: Summary and Recommendations of the Fifth International Workshop-Conference on Gestational Diabetes Mellitus. Diabetes Care. 2007, 30 (S2): S251-S260.CrossRefPubMed
38.
go back to reference Carpenter MW, Coustan DR: Criteria for screening tests for gestational diabetes. Am J Obstet Gynecol. 1982, 144 (7): 768-773.PubMed Carpenter MW, Coustan DR: Criteria for screening tests for gestational diabetes. Am J Obstet Gynecol. 1982, 144 (7): 768-773.PubMed
39.
go back to reference Alberti KGMM, Zimmet PZ, WHO Consultation: Definition, diagnosis and classification of diabetes mellitus and its complications, Part 1: Diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabet Med. 1998, 15: 539-553. 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S.CrossRefPubMed Alberti KGMM, Zimmet PZ, WHO Consultation: Definition, diagnosis and classification of diabetes mellitus and its complications, Part 1: Diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabet Med. 1998, 15: 539-553. 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S.CrossRefPubMed
40.
go back to reference Reichelt AJ, Oppermann MLR, Schmidt MI: Recomendações da 2ª reunião do grupo de trabalho em diabetes e gravidez. Arq Bras Endocrinol Metab. 2002, 46 (5): 574-581. 10.1590/S0004-27302002000500012.CrossRef Reichelt AJ, Oppermann MLR, Schmidt MI: Recomendações da 2ª reunião do grupo de trabalho em diabetes e gravidez. Arq Bras Endocrinol Metab. 2002, 46 (5): 574-581. 10.1590/S0004-27302002000500012.CrossRef
41.
go back to reference Professional Practice Committee/American Diabetes Association: Clinical practice recommendations. Diabetes Care. 2004, 27 (Suppl. 1): S5-10. Professional Practice Committee/American Diabetes Association: Clinical practice recommendations. Diabetes Care. 2004, 27 (Suppl. 1): S5-10.
42.
go back to reference American Diabetes Association: Diagnosis and classification of diabetes mellitus. Diabetes Care. 2009, 32 (1): 62-7.CrossRef American Diabetes Association: Diagnosis and classification of diabetes mellitus. Diabetes Care. 2009, 32 (1): 62-7.CrossRef
43.
go back to reference Brasil. Ministério da Saúde. Secretaria de Atenção à Saúde. Departamento de Ações Programáticas Estratégicas. Gestação de alto risco: manual técnico/Ministério da Saúde, Secretaria de Atenção à Saúde: Departamento de Ações Programáticas Estratégicas. 2010, Brasília: Editora do Ministério da Saúde, 302-5ª Brasil. Ministério da Saúde. Secretaria de Atenção à Saúde. Departamento de Ações Programáticas Estratégicas. Gestação de alto risco: manual técnico/Ministério da Saúde, Secretaria de Atenção à Saúde: Departamento de Ações Programáticas Estratégicas. 2010, Brasília: Editora do Ministério da Saúde, 302-5ª
44.
go back to reference Metzger BE, Lowe LP, Dyer AR, Trimble ER, Chaovarindr U, Coustan DR, Hadden DR, McCance DR, Hod M, McIntyre HD, Oats JJ, Persson B, Rogers MS, Sacks DA, HAPO Study Cooperative Research Group: Hyperglycemia and adverse pregnancy outcomes. The HAPO Study cooperative research group. N Engl J Med. 2008, 358: 1991-2002.CrossRefPubMed Metzger BE, Lowe LP, Dyer AR, Trimble ER, Chaovarindr U, Coustan DR, Hadden DR, McCance DR, Hod M, McIntyre HD, Oats JJ, Persson B, Rogers MS, Sacks DA, HAPO Study Cooperative Research Group: Hyperglycemia and adverse pregnancy outcomes. The HAPO Study cooperative research group. N Engl J Med. 2008, 358: 1991-2002.CrossRefPubMed
45.
go back to reference International Association of Diabetes and Pregnancy Study Groups Consensus Panel: International Association of Diabetes and Pregnancy Study Groups Recommendations on the Diagnosis and Classification of Hyperglycemia in Pregnancy. Diabetes Care. 2010, 33: 676-682.PubMedCentralCrossRef International Association of Diabetes and Pregnancy Study Groups Consensus Panel: International Association of Diabetes and Pregnancy Study Groups Recommendations on the Diagnosis and Classification of Hyperglycemia in Pregnancy. Diabetes Care. 2010, 33: 676-682.PubMedCentralCrossRef
46.
47.
go back to reference Negrato CA, Montenegro RM, Mattar R, Zajdenverg L, Francisco RP, Pereira BG, Sancovski M, Torloni MR, Dib SA, Viggiano CE, Golbert A, Moisés EC, Favaro MI, Calderon IM, Fusaro S, Piliakas VD, Dias JP, Gomes MB, Jovanovic L: Dysglycemias in pregnancy: from diagnosis to treatment. Brazilian consensus statement. Diabetol Metab Syndr. 2010, 2: 27-10.1186/1758-5996-2-27.PubMedCentralCrossRefPubMed Negrato CA, Montenegro RM, Mattar R, Zajdenverg L, Francisco RP, Pereira BG, Sancovski M, Torloni MR, Dib SA, Viggiano CE, Golbert A, Moisés EC, Favaro MI, Calderon IM, Fusaro S, Piliakas VD, Dias JP, Gomes MB, Jovanovic L: Dysglycemias in pregnancy: from diagnosis to treatment. Brazilian consensus statement. Diabetol Metab Syndr. 2010, 2: 27-10.1186/1758-5996-2-27.PubMedCentralCrossRefPubMed
Metadata
Title
Historical facts of screening and diagnosing diabetes in pregnancy
Authors
Carlos Antonio Negrato
Marilia Brito Gomes
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Diabetology & Metabolic Syndrome / Issue 1/2013
Electronic ISSN: 1758-5996
DOI
https://doi.org/10.1186/1758-5996-5-22

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