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Published in: Diabetology & Metabolic Syndrome 1/2010

Open Access 01-12-2010 | Research

Low and moderate, rather than high intensity strength exercise induces benefit regarding plasma lipid profile

Authors: Fabio S Lira, Alex S Yamashita, Marco C Uchida, Nelo E Zanchi, Bruno Gualano, Eivor Martins Jr, Erico C Caperuto, Marília Seelaender

Published in: Diabetology & Metabolic Syndrome | Issue 1/2010

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Abstract

Background

The effects of chronic aerobic exercise upon lipid profile has been previously demonstrated, but few studies showed this effect under resistance exercise conditions.

Objective

The aim of this study was to examine the effects of different resistance exercise loads on blood lipids.

Methods

Thirty healthy, untrained male volunteers were allocated randomly into four groups based at different percentages of one repetition maximum (1 RM); 50%-1 RM, 75%-1 RM, 90%-1 RM, and 110%-1 RM. The total volume (sets × reps × load) of the exercise was equalized. The lipid profile (Triglycerides [TG], HDL-cholesterol [HDL-c], LDL-cholesterol, and Total cholesterol) was determined at rest and after 1, 24, 48 and 72 h of resistance exercise.

Results

The 75%-1 RM group demonstrated greater TG reduction when compared to other groups (p < 0.05). Additionally, the 110%-1 RM group presented an increased TG concentration when compared to 50% and 75% groups (p = 0.01, p = 0.01, respectively). HDL-c concentration was significantly greater after resistance exercise in 50%-1 RM and 75%-1 RM when compared to 110%-1 RM group (p = 0.004 and p = 0.03, respectively). Accordingly, the 50%-1 RM group had greater HDL-c concentration than 110%-1 RM group after 48 h (p = 0.05) and 72 h (p = 0.004), respectively. Finally, The 50% group has showed lesser LDL-c concentration than 110% group after 24 h (p = 0.007). No significant difference was found in Total Cholesterol concentrations.

Conclusion

These results indicate that the acute resistance exercise may induce changes in lipid profile in a specific-intensity manner. Overall, low and moderate exercise intensities appear to be promoting more benefits on lipid profile than high intensity. Long term studies should confirm these findings.
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Literature
1.
go back to reference Leaf DA: The effect of physical exercise on reverse cholesterol transport. Metabolism. 2003, 52: 950-7. 10.1016/S0026-0495(03)00147-1.CrossRefPubMed Leaf DA: The effect of physical exercise on reverse cholesterol transport. Metabolism. 2003, 52: 950-7. 10.1016/S0026-0495(03)00147-1.CrossRefPubMed
2.
go back to reference Durstine JL, Grandjean PW, Cox CA, Thompson PD: Lipids, lipoproteins, and exercise. Journal of Cardiopulmonary Rehabilitation. 2002, 22: 385-98. 10.1097/00008483-200211000-00002.CrossRefPubMed Durstine JL, Grandjean PW, Cox CA, Thompson PD: Lipids, lipoproteins, and exercise. Journal of Cardiopulmonary Rehabilitation. 2002, 22: 385-98. 10.1097/00008483-200211000-00002.CrossRefPubMed
3.
go back to reference Belmonte MA, Aoki MS, Tavares FL, Seelaender MC: Rat myocellular and perimysial intramuscular triacylglycerol: a histological approach. Med Sci Sports Exerc. 2004, 36: 60-7. 10.1249/01.MSS.0000106170.26822.55.CrossRefPubMed Belmonte MA, Aoki MS, Tavares FL, Seelaender MC: Rat myocellular and perimysial intramuscular triacylglycerol: a histological approach. Med Sci Sports Exerc. 2004, 36: 60-7. 10.1249/01.MSS.0000106170.26822.55.CrossRefPubMed
4.
go back to reference Lira FS, Tavares FL, Yamashita AS, Koyama CH, Alves MJ, Caperuto EC, Batista ML, Seelaender M: Effect of endurance training upon lipid metabolism in the liver of cachectic tumour-bearing rats. Cell Biochem Funct. 2008, 26: 701-8. 10.1002/cbf.1495.CrossRefPubMed Lira FS, Tavares FL, Yamashita AS, Koyama CH, Alves MJ, Caperuto EC, Batista ML, Seelaender M: Effect of endurance training upon lipid metabolism in the liver of cachectic tumour-bearing rats. Cell Biochem Funct. 2008, 26: 701-8. 10.1002/cbf.1495.CrossRefPubMed
5.
go back to reference Epstein FH: Relationship between low cholesterol and disease. Evidence from epidemiological studies and preventive trials. Ann N Y Acad Sci. 1995, 17: 482-90. Epstein FH: Relationship between low cholesterol and disease. Evidence from epidemiological studies and preventive trials. Ann N Y Acad Sci. 1995, 17: 482-90.
6.
go back to reference Sallinen J, Fogelholm M, Volek JS, Kraemer WJ, Alen M, Häkkinen K: Effects of strength training and reduced training on functional performance and metabolic health indicators in middle-aged men. Int J Sports Med. 2007, 28: 815-22. 10.1055/s-2007-964901.CrossRefPubMed Sallinen J, Fogelholm M, Volek JS, Kraemer WJ, Alen M, Häkkinen K: Effects of strength training and reduced training on functional performance and metabolic health indicators in middle-aged men. Int J Sports Med. 2007, 28: 815-22. 10.1055/s-2007-964901.CrossRefPubMed
7.
go back to reference Elliott KJ, Sale C, Cable NT: Effects of resistance training and detraining on muscle strength and blood lipid profiles in postmenopausal women. Br J Sports Med. 2002, 36: 340-5. 10.1136/bjsm.36.5.340.PubMedCentralCrossRefPubMed Elliott KJ, Sale C, Cable NT: Effects of resistance training and detraining on muscle strength and blood lipid profiles in postmenopausal women. Br J Sports Med. 2002, 36: 340-5. 10.1136/bjsm.36.5.340.PubMedCentralCrossRefPubMed
8.
go back to reference Kokkinos PF, Hurley BF, Vaccaro P, Patterson JC, Gardner LB, Ostrove SM, Goldberg AP: Effects of low- and high-repetition resistive training on lipoprotein-lipid profiles. Med Sci Sports Exerc. 1988, 20: 50-4. 10.1249/00005768-198802000-00007.CrossRefPubMed Kokkinos PF, Hurley BF, Vaccaro P, Patterson JC, Gardner LB, Ostrove SM, Goldberg AP: Effects of low- and high-repetition resistive training on lipoprotein-lipid profiles. Med Sci Sports Exerc. 1988, 20: 50-4. 10.1249/00005768-198802000-00007.CrossRefPubMed
9.
go back to reference Kelley GA, Kelley KS: Impact of progressive resistance training on lipids and lipoproteins in adults: A meta-analysis of randomized controlled trials. Preventive Medicine. 2009, 48: 9-19. 10.1016/j.ypmed.2008.10.010.CrossRefPubMed Kelley GA, Kelley KS: Impact of progressive resistance training on lipids and lipoproteins in adults: A meta-analysis of randomized controlled trials. Preventive Medicine. 2009, 48: 9-19. 10.1016/j.ypmed.2008.10.010.CrossRefPubMed
10.
go back to reference Park DH, Ransone JW: Effects of submaximal exercise on high-density lipoprotein-cholesterol subfractions. Int J Sports Med. 2003, 24: 245-51. 10.1055/s-2003-39505.CrossRefPubMed Park DH, Ransone JW: Effects of submaximal exercise on high-density lipoprotein-cholesterol subfractions. Int J Sports Med. 2003, 24: 245-51. 10.1055/s-2003-39505.CrossRefPubMed
11.
go back to reference Shimano T, Kraemer WJ, Spiering BA, Volek JS, Hatfield DL, Silvestre R, Vingren JL, Fragala MS, Maresh CM, Fleck SJ, Newton RU, Preuwenberg LP, Häkkinen K: Relationship between the number of repetitions and selected percentages of one repetition maximum in free weight exercises in trained and untrained men. J Strength Cond Res. 2006, 20: 819-23. 10.1519/R-18195.1.PubMed Shimano T, Kraemer WJ, Spiering BA, Volek JS, Hatfield DL, Silvestre R, Vingren JL, Fragala MS, Maresh CM, Fleck SJ, Newton RU, Preuwenberg LP, Häkkinen K: Relationship between the number of repetitions and selected percentages of one repetition maximum in free weight exercises in trained and untrained men. J Strength Cond Res. 2006, 20: 819-23. 10.1519/R-18195.1.PubMed
12.
go back to reference Uchida MC, Nosaka K, Ugrinowitsch C, Yamashita A, Martins E, Moriscot AS, Aoki MS: Effect of bench press exercise intensity on muscle soreness and inflammatory mediators. J Sports Sci. 2009, 27: 499-507. 10.1080/02640410802632144.CrossRefPubMed Uchida MC, Nosaka K, Ugrinowitsch C, Yamashita A, Martins E, Moriscot AS, Aoki MS: Effect of bench press exercise intensity on muscle soreness and inflammatory mediators. J Sports Sci. 2009, 27: 499-507. 10.1080/02640410802632144.CrossRefPubMed
13.
go back to reference Ahtiainen JP, Pakarinen A, Alen M, Kraemer WJ, Häkkinen K: Short vs. long rest period between the sets in hypertrophic resistance training: influence on muscle strength, size, and hormonal adaptations in trained men. J Strength Cond Res. 2005, 19: 572-82. 10.1519/15604.1.PubMed Ahtiainen JP, Pakarinen A, Alen M, Kraemer WJ, Häkkinen K: Short vs. long rest period between the sets in hypertrophic resistance training: influence on muscle strength, size, and hormonal adaptations in trained men. J Strength Cond Res. 2005, 19: 572-82. 10.1519/15604.1.PubMed
14.
go back to reference Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of LDL-cholesterol in plasma, without use of the ultracentrifuge. Clin Clem. 1972, 18: 499-502. Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of LDL-cholesterol in plasma, without use of the ultracentrifuge. Clin Clem. 1972, 18: 499-502.
15.
go back to reference Campaigne BN, Fontaine RN, Park MS, Rymaszewski ZJ: Reversal cholesterol transport with acute exercise. Med Sci Sports Exerc. 1993, 25: 1346-51.CrossRefPubMed Campaigne BN, Fontaine RN, Park MS, Rymaszewski ZJ: Reversal cholesterol transport with acute exercise. Med Sci Sports Exerc. 1993, 25: 1346-51.CrossRefPubMed
16.
go back to reference James AP, Slivkoff-Clark K, Mamo JC: Prior exercise does not affect chylomicron particle number following a mixed meal of moderate fat content. Lipids Health Dis. 2007, 30: 6-8. James AP, Slivkoff-Clark K, Mamo JC: Prior exercise does not affect chylomicron particle number following a mixed meal of moderate fat content. Lipids Health Dis. 2007, 30: 6-8.
17.
go back to reference Wallace MB, Moffatt RJ, Haymes EM, Green NR: Acute effects of resistance exercise on parameters of lipoprotein metabolism. Med Sci Sports Exerc. 1991, 23: 199-204.CrossRefPubMed Wallace MB, Moffatt RJ, Haymes EM, Green NR: Acute effects of resistance exercise on parameters of lipoprotein metabolism. Med Sci Sports Exerc. 1991, 23: 199-204.CrossRefPubMed
18.
go back to reference Prabhakaran B, Dowling EA, Branch JD, Swain DP, Leutholtz BC: Effect of 14 weeks of resistance training on lipid profile and body fat percentage in premenopausal women. Br J Sports Med. 1999, 33: 190-5. 10.1136/bjsm.33.3.190.PubMedCentralCrossRefPubMed Prabhakaran B, Dowling EA, Branch JD, Swain DP, Leutholtz BC: Effect of 14 weeks of resistance training on lipid profile and body fat percentage in premenopausal women. Br J Sports Med. 1999, 33: 190-5. 10.1136/bjsm.33.3.190.PubMedCentralCrossRefPubMed
19.
go back to reference Hill S, Bermingham MA, Knight PK: Lipid metabolism in young men after acute resistance exercise at two different intensities. J Sci Med Sport. 2005, 8: 441-5. 10.1016/S1440-2440(05)80059-3.CrossRefPubMed Hill S, Bermingham MA, Knight PK: Lipid metabolism in young men after acute resistance exercise at two different intensities. J Sci Med Sport. 2005, 8: 441-5. 10.1016/S1440-2440(05)80059-3.CrossRefPubMed
20.
go back to reference Ferguson MA, Alderson NL, Trost SG, Essig DA, Burke JR, Durstine JL: Effects of four different single exercise sessions on lipids, lipoproteins and lipoprotein lipase. J Appl Physiol. 1998, 85: 1169-74.PubMed Ferguson MA, Alderson NL, Trost SG, Essig DA, Burke JR, Durstine JL: Effects of four different single exercise sessions on lipids, lipoproteins and lipoprotein lipase. J Appl Physiol. 1998, 85: 1169-74.PubMed
21.
go back to reference Campaigne BN, Fontaine RN, Park MS, Rymaszewski ZJ: Reversal cholesterol transport with acute exercise. Med Sci Sports Exerc. 1993, 25: 1346-51.CrossRefPubMed Campaigne BN, Fontaine RN, Park MS, Rymaszewski ZJ: Reversal cholesterol transport with acute exercise. Med Sci Sports Exerc. 1993, 25: 1346-51.CrossRefPubMed
22.
go back to reference Magkos F, Tsekouras YE, Prentzas KI, Basioukas KN, Matsama SG, Yanni AE, Kavouras SA, Sidossis LS: Acute exercise-induced changes in basal VLDL-triglyceride kinetics leading to hypotriglyceridemia manifest more readily after resistance than endurance exercise. J Appl Physiol. 2008, 31: 1228-36. 10.1152/japplphysiol.90761.2008.CrossRef Magkos F, Tsekouras YE, Prentzas KI, Basioukas KN, Matsama SG, Yanni AE, Kavouras SA, Sidossis LS: Acute exercise-induced changes in basal VLDL-triglyceride kinetics leading to hypotriglyceridemia manifest more readily after resistance than endurance exercise. J Appl Physiol. 2008, 31: 1228-36. 10.1152/japplphysiol.90761.2008.CrossRef
23.
go back to reference Magkos F, Patterson BW, Mohammed BS, Mittendorfer B: A single 1-h bout of evening exercise increases basal ffa flux without affecting VLDL-triglyceride and VLDL-apolipoprotein B-100 kinetics in untrained lean men. Am J Physiol Endocrinol Metab. 2007, 292: E1568-74. 10.1152/ajpendo.00636.2006.CrossRefPubMed Magkos F, Patterson BW, Mohammed BS, Mittendorfer B: A single 1-h bout of evening exercise increases basal ffa flux without affecting VLDL-triglyceride and VLDL-apolipoprotein B-100 kinetics in untrained lean men. Am J Physiol Endocrinol Metab. 2007, 292: E1568-74. 10.1152/ajpendo.00636.2006.CrossRefPubMed
24.
go back to reference Tsekouras YE, Magkos F, Prentzas KI, Basioukas KN, Matsama SG, Yanni AE, Kavouras SA, Sidossis LS: A single bout of whole-body resistance exercise augments basal VLDL-triacylglycerol removal from plasma in healthy untrained men. Clin Sci (Lond). 2008, 13: 146-57. Tsekouras YE, Magkos F, Prentzas KI, Basioukas KN, Matsama SG, Yanni AE, Kavouras SA, Sidossis LS: A single bout of whole-body resistance exercise augments basal VLDL-triacylglycerol removal from plasma in healthy untrained men. Clin Sci (Lond). 2008, 13: 146-57.
25.
go back to reference Seip RL, Semenkovich CF: Skeletal muscle lipoprotein lipase: molecular regulation and physiological effects in relation to exercise. Exerc Sport Sci Rev. 1998, 26: 191-218. 10.1249/00003677-199800260-00010.CrossRefPubMed Seip RL, Semenkovich CF: Skeletal muscle lipoprotein lipase: molecular regulation and physiological effects in relation to exercise. Exerc Sport Sci Rev. 1998, 26: 191-218. 10.1249/00003677-199800260-00010.CrossRefPubMed
26.
go back to reference Mondon CE, Dolkas CB, Tobey T, Reaven GM: Causes of the triglyceride-lowering effect of exercise training in rats. J Appl Physiol. 1984, 57: 1466-71.PubMed Mondon CE, Dolkas CB, Tobey T, Reaven GM: Causes of the triglyceride-lowering effect of exercise training in rats. J Appl Physiol. 1984, 57: 1466-71.PubMed
27.
go back to reference Pilegaard H, Ordway GA, Saltin B, Neufer PD: Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise. Am J Physiol Endocrinol Metab. 2000, 279: E806-14.PubMed Pilegaard H, Ordway GA, Saltin B, Neufer PD: Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise. Am J Physiol Endocrinol Metab. 2000, 279: E806-14.PubMed
28.
go back to reference Lira FS, Zanchi NE, Lima-Silva AE, Pires FO, Bertuzzi RC, Santos RV, Caperuto EC, Kiss MA, Seelaender M: Acute high-intensity exercise with low energy expenditure reduced LDL-c and total cholesterol in men. Eur J Appl Physiol. 2009, 107: 203-10. 10.1007/s00421-009-1115-5.CrossRefPubMed Lira FS, Zanchi NE, Lima-Silva AE, Pires FO, Bertuzzi RC, Santos RV, Caperuto EC, Kiss MA, Seelaender M: Acute high-intensity exercise with low energy expenditure reduced LDL-c and total cholesterol in men. Eur J Appl Physiol. 2009, 107: 203-10. 10.1007/s00421-009-1115-5.CrossRefPubMed
29.
go back to reference Lira FS, Rosa JC, Lima-Silva AE, Souza HA, Caperuto EC, Seelaender MC, Damaso AR, Oyama LM, Santos RV: Sedentary subjects have higher PAI-1 and lipoproteins levels than highly trained athletes. Diabetol Metab Syndr. 2010, 2: 7-10.1186/1758-5996-2-7.PubMedCentralCrossRefPubMed Lira FS, Rosa JC, Lima-Silva AE, Souza HA, Caperuto EC, Seelaender MC, Damaso AR, Oyama LM, Santos RV: Sedentary subjects have higher PAI-1 and lipoproteins levels than highly trained athletes. Diabetol Metab Syndr. 2010, 2: 7-10.1186/1758-5996-2-7.PubMedCentralCrossRefPubMed
30.
go back to reference Bweir S, Al-Jarrah M, Almalty AM, Maayah M, Smirnova IV, Novikova L, Stehno-Bittel L: Resistance exercise training lowers HbA1c more than aerobic training in adults with type 2 diabetes. Diabetol Metab Syndr. 2009, 1: 27-10.1186/1758-5996-1-27.PubMedCentralCrossRefPubMed Bweir S, Al-Jarrah M, Almalty AM, Maayah M, Smirnova IV, Novikova L, Stehno-Bittel L: Resistance exercise training lowers HbA1c more than aerobic training in adults with type 2 diabetes. Diabetol Metab Syndr. 2009, 1: 27-10.1186/1758-5996-1-27.PubMedCentralCrossRefPubMed
Metadata
Title
Low and moderate, rather than high intensity strength exercise induces benefit regarding plasma lipid profile
Authors
Fabio S Lira
Alex S Yamashita
Marco C Uchida
Nelo E Zanchi
Bruno Gualano
Eivor Martins Jr
Erico C Caperuto
Marília Seelaender
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Diabetology & Metabolic Syndrome / Issue 1/2010
Electronic ISSN: 1758-5996
DOI
https://doi.org/10.1186/1758-5996-2-31

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